Patents by Inventor Gee-Hong Kuo

Gee-Hong Kuo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED PYRROLINE KINASE INHIBITORS
    Publication number: 20090176806
    Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
    Type: Application
    Filed: March 11, 2009
    Publication date: July 9, 2009
    Inventors: Han-Cheng Zhang, Gee-Hong Kuo, Bruce E. Maryanoff, Hong Ye, David O'Neill, Lan Shen, Keith Demarest, Bruce R. Conway, David F. McComsey
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20090131489
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: January 23, 2009
    Publication date: May 21, 2009
    Inventors: Gee-Hong KUO, Lan Shen, Aihua Wang, Yan Zhang
  • Substituted pyrroline kinase inhibitors
    Patent number: 7524858
    Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: April 28, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Han-Cheng Zhang, Gee-Hong Kuo, Bruce E. Maryanoff, Hong Ye, David O'Neill, Lan Shen, David F. McComsey
  • 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7498351
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: March 3, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Lan Shen, Aihua Wang, Yan Zhang
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20080269336
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: June 23, 2008
    Publication date: October 30, 2008
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7425649
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: September 16, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • GPR40 AGONISTS
    Publication number: 20080176912
    Abstract: The invention is directed to compounds of Formula (I) useful as GPR40 agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, insulin resistance, hyperglycemia, obesity, diabetes such as NIDDM, and other disorders related to lipid metabolism, energy homeostasis, and complications thereof, using compounds of the invention are also described.
    Type: Application
    Filed: November 13, 2007
    Publication date: July 24, 2008
    Inventors: Gee-Hong Kuo, Fengbin Song, Joseph Gunnet, Keith Demarest
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20080085927
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: October 15, 2007
    Publication date: April 10, 2008
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7301050
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: November 27, 2007
    Assignee: Janssen Pharmaceutical N.V.
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan R. DeAngelis
  • 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS
    Publication number: 20070265304
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Application
    Filed: May 10, 2007
    Publication date: November 15, 2007
    Inventors: Thomas Rano, Gee-Hong Kuo, Ellen Sieber-McMaster, Keith T. Demarest, Patricia Pelton, Aihua Wang
  • 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS
    Publication number: 20070265252
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Application
    Filed: May 10, 2007
    Publication date: November 15, 2007
    Inventors: Gee-Hong Kuo, Aihua Wang, Thomas Rano, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • BENZOAZEPIN-OXY-ACETIC ACID DERIVATIVES AS PPAR-DELTA AGONISTS USED FOR THE INCREASE OF HDL-C, LOWER LDL-C AND LOWER CHOLESTEROL
    Publication number: 20070244094
    Abstract: The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL-cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof, using compounds of the invention are also described.
    Type: Application
    Filed: April 17, 2007
    Publication date: October 18, 2007
    Inventors: Gee-Hong Kuo, Yan Zhang, Lan Shen, Songfeng Lu, Keith T. Demarest, Patricia Peiton
  • Macroheterocyclic compounds as kinase inhibitors
    Publication number: 20070088019
    Abstract: This invention is directed to macroheterocyclic compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disease, condition or disorder.
    Type: Application
    Filed: September 27, 2006
    Publication date: April 19, 2007
    Inventors: Han-Cheng Zhang, Gee-Hong Kuo, Bruce Maryanoff, Hong Ye
  • Substituted triazine kinase inhibitors
    Patent number: 7205298
    Abstract: The present invention provides substituted 1,3,5-triazine compounds as kinase inhibitors and a method for treating or ameliorating a kinase mediated disorder.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: April 17, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Alan DeAngelis, Aihua Wang, Yan Zhang, Stuart L. Emanuel, Steve Middleton
  • Substituted pyrroline kinase inhibitors
    Patent number: 7125878
    Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: October 24, 2006
    Assignee: Janssen Pharmaceutica
    Inventors: Han-Cheng Zhang, Gee-Hong Kuo, Bruce E. Maryanoff, Hong Ye, David O'Neill, Lan Shen, Keith Demarest, Bruce R. Conway, David F. McComsey
  • Substituted pyrroline kinase inhibitors
    Publication number: 20060205763
    Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
    Type: Application
    Filed: May 17, 2006
    Publication date: September 14, 2006
    Inventors: Han-Cheng Zhang, Gee-Hong Kuo, Bruce Maryanoff, Hong Ye, David O'Neill, Lan Shen, Keith Demarest, Bruce Conway, David McComsey
  • Substituted pyrroline kinase inhibitors
    Publication number: 20060205762
    Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
    Type: Application
    Filed: May 17, 2006
    Publication date: September 14, 2006
    Inventors: Han-Cheng Zhang, Gee-Hong Kuo, Bruce Maryanoff, Hong Ye, David O'Neill, Lan Shen, Keith Demarest, Bruce Conway, David McComsey
  • 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Publication number: 20060074246
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: November 15, 2005
    Publication date: April 6, 2006
    Inventors: Gee-Hong Kuo, Lan Shen, Aihua Wang, Yan Zhang
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7015329
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: March 21, 2006
    Assignee: Janssen Pharmaceutica N. V.
    Inventors: Gee-Hong Kuo, Lan Shen, Aihua Wang, Yan Zhang
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Publication number: 20060058393
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: September 14, 2005
    Publication date: March 16, 2006
    Inventors: Alan DeAngelis, Keith Demarest, Gee-Hong Kuo, Patricia Pelton, Aihua Wang, Rui Zhang