Patents by Inventor Geert J. Sterk

Geert J. Sterk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted ethanolamine esters
    Patent number: 5599966
    Abstract: Compounds of the formula (I): Ar.sub.1 --CH(OH)--CH.sub.2 --NH--CH.sub.2 --X--CH.sub.2 --E--(CH.sub.2).sub.n --Y--Ar.sub.2, in which the substituents and symbols have the meanings given in the description, are novel active compounds having, in particular, a broncholytic action.
    Type: Grant
    Filed: April 17, 1995
    Date of Patent: February 4, 1997
    Assignee: BYK Nederland BV
    Inventors: Jan Bron, Geert J. Sterk, Hendrik Timmerman, Meta E. J. Veerman, Jan F. Van Der Werf
  • Thiazolidine derivatives
    Patent number: 5385922
    Abstract: Thiazolidine derivatives containing at least one organic nitrate ester group have cardiovascular activity.
    Type: Grant
    Filed: March 4, 1993
    Date of Patent: January 31, 1995
    Assignee: Cedona Pharmaceuticals B.V.
    Inventors: Jan Bron, Geert J. Sterk, Hendrik Timmerman, Jan. F. Van Der Werf
  • 1,4-dihydropyridine derivatives
    Patent number: 5378718
    Abstract: Compounds a formula (I) ##STR1## wherein the substituents and symbols have the meanings given in the specification, are new compounds with marked cardiovascular activity.
    Type: Grant
    Filed: January 22, 1993
    Date of Patent: January 3, 1995
    Assignee: Cedona Pharmaceuticals B.V.
    Inventors: Jan Bron, Geert J. Sterk, Hendrik Timmerman, Jan F. Van Der Werf
  • Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance
    Patent number: 5049694
    Abstract: The invention relates to pharmaceutical compositions containing novel nitrate esters, of which it was found that they are useful for the treatment of ischemiatic heart diseases, decompensatio cordis, myocardial infarction and hypertension.
    Type: Grant
    Filed: September 14, 1989
    Date of Patent: September 17, 1991
    Assignee: Cedona Pharmaceuticals B.V.
    Inventors: Jan Bron, Geert J. Sterk, Jan F. van der Werf, Hendrik Timmerman
  • N-(W-substituted alkyl)-'-(imidazol-4-yl)alkyl)guanidine
    Patent number: 5010095
    Abstract: N-(2-substituted alkyl)-N'[(imidazole-4-yl)alkylguanidines are provided by the reaction of a primary amine with benzoylisothiocyante to a benzoylthiourea derivative, followed by hydrolysis of this derivative to form the corresponding thiourea, converting this thiourea with methyliodide into an isothiourea and producing the desired compound by reaction of the isothiourea with aminopropylimidazole or aminoethylimidazole. The compound can be converted into an acid addition salt or the free compound obtained from such salt. The compounds are useful as the active ingredient in pharmaceutical compositions for the treatment of congestion, heart failure and some allergic conditions.
    Type: Grant
    Filed: November 23, 1988
    Date of Patent: April 23, 1991
    Assignee: Cedona Pharmaceuticals B.V.
    Inventors: Geert J. Sterk, Henk Timmerman, Henk van der Goot