Patents by Inventor Geert Jan Sterk

Geert Jan Sterk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperazino-derivatives and their use as PDE4 inhibitor
    Patent number: 7022696
    Abstract: The compounds of formula I in which R1, R2, R3, A, X, s and R9 have the meanings as given in the description are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 4, 2006
    Assignee: Altana Pharma AG
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Phthalazinone-piperidino-derivatives as PDE4 inhibitors
    Patent number: 6953853
    Abstract: The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: October 11, 2005
    Assignee: Altana Pharma AG
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Compounds effective as ?2-adrenoreceptor agonists as well as PDE4-inhibitors
    Patent number: 6933296
    Abstract: The compounds of formula I in which Ar1, A, R6, R7, R8 and Ar2 have the meanings as given in the description are novel effective bronchial therapeutics
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: August 23, 2005
    Assignee: Altana Pharma B.V.
    Inventor: Geert Jan Sterk
  • Tetrahydrothiopy ranphthalazinone derivatives as PDE4 inhibitors
    Patent number: 6846821
    Abstract: The compounds of formula (I) in which R1, R2, A and Ar have the meanings as given in the description are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: January 25, 2005
    Assignee: Altana Pharma, AG
    Inventor: Geert Jan Sterk
  • (Dihydro) isoquinoline derivatives as phosphodiesterase inhibitors
    Patent number: 6818651
    Abstract: 3,4-Dihydroisoquinoline and isoquinoline compounds of formula I, in which Ar represents a phenyl raidcal of the formulae IIa, IIb or IIc are novel effective PDE7 inhibitors.
    Type: Grant
    Filed: August 21, 2003
    Date of Patent: November 16, 2004
    Assignee: Altana Pharma AG
    Inventors: Steffen Weinbrenner, Beate Schmidt, Gerhard Grundler, Josef Stadlwieser, Armin Hatzelmann, Geert Jan Sterk
  • Piperazino-derivatives and their use as pde4 inhibitor
    Publication number: 20040132721
    Abstract: The compounds of formula I, in which R1, R2, R3, A, X, s and R9 have the meanings as given in the description are novel effecfive PDE4 inhibitors.
    Type: Application
    Filed: October 23, 2003
    Publication date: July 8, 2004
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • Novel phthalazinones
    Publication number: 20040127707
    Abstract: The compounds of formula I in which R1, R2, R3, R4 and R5 have the meanings as given in the description are PDE4/7 inhibitors.
    Type: Application
    Filed: October 23, 2003
    Publication date: July 1, 2004
    Inventor: Geert Jan Sterk
  • Phthalazinone derivatives as PDE4 inhibitors
    Patent number: 6756371
    Abstract: The compounds of formula (I) in which R1, R2, A, B and Ar have the meanings as given in the description are novel effective PDe4 inhibitors
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: June 29, 2004
    Assignee: Altana Pharma AG
    Inventor: Geert Jan Sterk
  • Phthalatyinone-piperidino-derivatives as pde4 inhibitors
    Publication number: 20040067946
    Abstract: The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: August 13, 2003
    Publication date: April 8, 2004
    Inventors: Gerhard Grundler, Beate Schmidt, Geert Jan Sterk
  • (Dihydro) Isoquinoline derivatives as phosphodiesterase inhibitors
    Publication number: 20040044212
    Abstract: 3,4-Dihydroisoquinoline and isoquinoline compounds of formula I, in which Ar represents a phenyl raidcal of the formulae IIa, IIb or IIc are novel effective PDE7 inhibitors.
    Type: Application
    Filed: August 21, 2003
    Publication date: March 4, 2004
    Inventors: Steffen Weinbrenner, Beate Schmidt, Gerlard Grundler, Josef Stadwieser, Armin Hatzelmann, Geert Jan Sterk
  • 1,4-dihydropyridine-5-carboxylic acid ester derivatives and method for the preparation thereof
    Patent number: 6689799
    Abstract: The present invention relates to ester derivatives of 1,4-dihydropyridine-5-carboxylic acid of formula (I) wherein R1, R2 and R3 may be a coumarin group. These compounds possess an anti-viral activity. Most of the anti-viral compounds known in the art are nucleoside-derivatives. Various viruses become resistent against these. Because the compounds according to the invention are not nucleoside-derivatives, they form a suitable alternative. The invention also relates to a method of preparing the anti-viral substances according to the invention.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: February 10, 2004
    Assignee: Rephartox
    Inventors: Geert Jan Sterk, Jan Fetze Van Der Werf
  • Compounds effective as beta-2 adrenoreceptor agonists as well pde4-inhibitors
    Publication number: 20030195215
    Abstract: The compounds of formula I in which Ar1, A, R6, R7, R8 and Ar2 have the meanings as given in the description are novel effective bronchial therapeutics.
    Type: Application
    Filed: April 2, 2003
    Publication date: October 16, 2003
    Inventor: Geert Jan Sterk
  • Tetrahydrothiopy ranphthalazinone derivatives as PDE4 inhibitors
    Publication number: 20030166655
    Abstract: The compounds of formula (I) in which R1, R2, A and Ar have the meanings as given in the description are novel effective PDE4 inhibitors.
    Type: Application
    Filed: February 25, 2003
    Publication date: September 4, 2003
    Applicant: Altana Pharma AG
    Inventor: Geert Jan Sterk
  • Tetrahydrothiopyranphthalazinone derivatives as PDE4 inhibitors
    Patent number: 6544993
    Abstract: The compounds of formula (I) in which R1, R2, A and Ar have the meanings as given in the description are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: April 8, 2003
    Assignee: Altana Pharma AG
    Inventor: Geert Jan Sterk
  • Dihydrobenzofurans
    Patent number: 6380196
    Abstract: Compounds of formula I, wherein Het represents a heterocycle having the meaning and R1, R2, R3 and R4 have the meanings as given in the description are novel effective bronchial therapeutics.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: April 30, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Wolf-Rüdiger Ulrich, Geert Jan Sterk, Margaretha van der Mey
  • Phthalazinone PDE III/IV inhibitors
    Patent number: 6255303
    Abstract: The compounds of formula (I) in which R1, R2, R3, R4, R5, X and Y have the meanings as given in the description are novel effective bronchial therapeutica.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: July 3, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Geert Jan Sterk, Margaretha van der Mey
  • Phthalazinones
    Patent number: 6103718
    Abstract: Compounds of formula I wherein R1, R2, R3, R4 and R5 have the means set forth in the description are selective cyclic nucleotide phosphodiesterase (PDE) inhibitors (specifically of type 4), which are effective bronchial therapeutics.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: August 15, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Geert Jan Sterk