Patents by Inventor Geert Jan VAN TETERING

Geert Jan VAN TETERING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED IGA ANTIBODIES AND METHODS OF USE
    Publication number: 20210395395
    Abstract: Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of treating disorders, including cancer, by administering an engineered IgA antibody described herein.
    Type: Application
    Filed: June 9, 2021
    Publication date: December 23, 2021
    Inventors: Jeanette Henrica Wilhelmina LEUSEN, Johannes Gerardus Maria EVERS, Geert Jan VAN TETERING
  • ENGINEERED IGA ANTIBODIES AND METHODS OF USE
    Publication number: 20210380720
    Abstract: Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of treating disorders, including cancer, by administering an engineered IgA antibody described herein.
    Type: Application
    Filed: June 9, 2021
    Publication date: December 9, 2021
    Inventors: Jeanette Henrica Wilhelmina LEUSEN, Johannes Gerardus Maria EVERS, Geert Jan VAN TETERING
  • COMPOSITIONS AND METHODS COMPRISING IgA ANTIBODY CONSTRUCTS
    Publication number: 20210332131
    Abstract: Provided herein are therapeutic agents, pharmaceutical compositions, and methods comprising an IgA constant region. The compositions and methods described herein facilitate binding of an antibody construct comprising an IgA constant domain to CD47 and an antigen for instance a tumor related antigen such as CD20 or CD19.
    Type: Application
    Filed: April 28, 2021
    Publication date: October 28, 2021
    Inventors: Mark De Boer, Jeannette Henrica Wilhelmina LEUSEN, Geert Jan VAN TETERING
  • Engineered IGA antibodies and methods of use
    Patent number: 11091562
    Abstract: Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of treating disorders, including cancer, by administering an engineered IgA antibody described herein.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: August 17, 2021
    Assignee: UMC Utrecht Holding B.V.
    Inventors: Jeanette Henrica Wilhelmina Leusen, Johannes Gerardus Maria Evers, Geert Jan Van Tetering
  • Engineered IgA antibodies and methods of use
    Patent number: 11059909
    Abstract: Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of treating disorders, including cancer, by administering an engineered IgA antibody described herein.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: July 13, 2021
    Assignee: UMC UTRECHT HOLDING B.V.
    Inventors: Jeanette Henrica Wilhelmina Leusen, Johannes Gerardus Maria Evers, Geert Jan Van Tetering
  • ENGINEERED IGA ANTIBODIES AND METHODS OF USE
    Publication number: 20210130462
    Abstract: Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of treating disorders, including cancer, by administering an engineered IgA antibody described herein.
    Type: Application
    Filed: November 6, 2020
    Publication date: May 6, 2021
    Inventors: Jeanette Henrica Wilhelmina LEUSEN, Johannes Gerardus Maria EVERS, Geert Jan VAN TETERING
  • ENGINEERED IGA ANTIBODIES AND METHODS OF USE
    Publication number: 20210122834
    Abstract: Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of treating disorders, including cancer, by administering an engineered IgA antibody described herein.
    Type: Application
    Filed: November 6, 2020
    Publication date: April 29, 2021
    Inventors: Jeanette Henrica Wilhelmina LEUSEN, Johannes Gerardus Maria EVERS, Geert Jan VAN TETERING