Abstract: The device (100) comprises a substrate (10) of a semiconductor material with a first and an opposite second surface (1,2) and a microelectromechanical (MEMS) element (50) which is provided with a fixed and a movable electrode (52, 51) that is present in a cavity (30). One of the electrodes (51,52) is defined in the substrate (10). The movable electrode (51) is movable towards and from the fixed electrode (52) between a first gapped position and a second position. The cavity (30) is opened through holes (18) in the substrate (10) that are exposed on the second surface (2) of the substrate (10). The cavity (30) has a height that is defined by at least one post (15) in the substrate (10), which laterally substantially surrounds the cavity (15).

Abstract: The invention relates to a device for melatonin treatment involving an adapting means which adapts the daily dose upon measurement of a body parameter of the patient or the user of the device.

Abstract: An implantable drug delivery system is proposed which does not need internal electronics, but can be activated from outside the body. The system comprises a device (10) for the controlled release of a substance, the device (10) comprising at least one compartment (20) in a substrate (11), the compartment (20) being closed by a valve (30), wherein the valve is openable and comprises at least a first material (31) and a second material (32), the opening and/or closing of the valve (30) being provided upon heating and/or cooling of the first and/or second material (31, 32), the first material (31) being heated by electromagnetic induction.

Abstract: In this disclosure a new type of pen is described which is able to modulate the trace of the pen in response to a sensory signal of the user, such as for example skin conductance or respiration. As is known, these types of sensory signals represent the mood of the user. By changing the trace of the pen from for example blue to red, a change in mood of the user can be expressed.

Abstract: The invention relates to a device for medical treatment decision support and/or monitoring the status of a patient, the device comprising a first measuring means at the ipsilateral side and a second measuring means at the contralateral side and a comparison means in order to find the optimal and/or suboptimal time for drug treatment and/or other medical treatment steps.

Abstract: The invention relates to an osmotic pump (1) comprising at least one chargeable material (30) whereby the osmotic pressure is caused by inducing and/or de-inducing charges within the material.

Abstract: The invention relates to a micropump comprising at least one gas releasing material which drives a piston towards a second material containing a drug material which is released through a semi permeable membrane and/or flow restrictor

Abstract: A wearable electronic device such as a wrist watch (60) is supplied with conventional clock with two pointers (32,33). The device displays a parameter indicative of how “cool” the wearer has been over the past period as a function of time, using the time axis of one of the pointers (32,33). “Coolness” can be based on the measurement of related physiological parameters like heart-rate, body temperature, movement, skin resistance or muscle activity. “Coolness” of a person is understood as being the ability to cope with stress. Therefore, the stability of physiological parameters can be used to derive a signal for the subjective trait called “coolness”. All physiological parameters can be measured by sensors (10) in the watch (60) or in the strap (50). The invention is used as a gadget for self expression and emotional feedback.

Abstract: This invention provides a device for the controlled release of a substance and a method of controllably releasing a substance from a compartment.

Abstract: The invention relates to a device for drug administration and/or monitoring the status of a patient, the device comprising a first and a second measuring means, and the time for using the second measuring means being set in accordance with the data of the first measuring means.

Abstract: The invention relates to a device for drug administration and/or monitoring the status of a patient, said device comprising at least one measuring means for measuring at least one body parameter of a patient for at least ?1 measuring cycle, the measuring means being located in or in the vicinity of a bio-implantable and/or bio-implementable needle.

Abstract: The invention relates to a method of packaging an electronic microsystem (200) and further to such a packaged device. With the method a packaged electronic microsystem (200) can be manufactured using a flexible foil (80) having conductive tracks (100) on at least on side of the flexible foil. The electronic microsystem (200) and the flexible foil (80) are arranged in a way that a sealed or even hermetic package can be realized and contact pads (210) of the electronic microsystem (200) are connected to conductive tracks (100) extending to the outer surface of the packaged device after folding the flexible foil (80) in the proposed way. No vias or throughholes in the flexible foil (80) are needed.

Abstract: The invention relates to a method of manufacturing a microsystem and further to such microsystem. With the method a microsystem can be manufactured by stacking pre-processed foils (10) having a conductive layer (11a,11b) on at least one side. After stacking, the foils (10) are sealed, using pressure and heat. Finally the microsystems are separated from the stack (S). The pre-processing of the foils (preferably done by means of a laser beam) comprises a selection of the following steps: (A) leaving the foil intact, (B) locally removing the conductive layer, (C) removing the conductive layer and partially evaporating the foil (10), and (D) removing both the conductive layer as well as foil (10), thus making holes in the foil (10). In combination with said stacking, it is possible to create cavities, freely suspended cantilevers and membranes. This opens up the possibility of manufacturing various microsystems, like MEMS devices and microfluidic systems.

Abstract: The invention relates to a device comprising an ingestible capsule which measures at least one body parameter and starts a drug release program upon predefined changes in the body parameter.

Abstract: The invention relates to a method of manufacturing a MEMS capacitor microphone and further to such MEMS capacitor microphone. With the method a MEMS capacitor microphone can be manufactured by stacking pre-processed foils (10) having a conductive layer (11a,11b) on at least one side. After stacking, the foils (10) are sealed, using pressure and heat. Finally the MEMS capacitor microphones are separated from the stack (S). The pre-processing of the foils (preferably done by means of a laser beam) comprises a selection of the following steps: (A) leaving the foil intact, (B) locally removing the conductive layer, (C) removing the conductive layer and partially evaporating the foil (10), and (D) removing both the conductive layer as well as foil (10), thus making holes in the foil (10). In combination with said stacking, it is possible to create cavities and membranes. This opens up the possibility of manufacturing MEMS capacitor microphone.

Abstract: The invention relates to a method of manufacturing a microsystem and further to such microsystem. With the method a microsystem can be manufactured by stacking pre-processed foils (10) having a conductive layer (11a, 11b) on at least one side. After stacking, the foils (10) are sealed, using pressure and heat. Finally the microsystems are separated from the stack (S). The pre-processing of the foils (preferably done by means of a laser beam) comprises a selection of the following steps: (A) leaving the foil intact, (B) locally removing the conductive layer, (C) removing the conductive layer and partially evaporating the foil (10), and (D) removing both the conductive layer as well as foil (10), thus making holes in the foil (10). In combination with said stacking, it is possible to create cavities, freely suspended cantilevers and membranes. This opens up the possibility of manufacturing various microsystems, like MEMS devices and microfluidic systems.