Patents by Inventor Geert Leroux-Roels

Geert Leroux-Roels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for predicting the efficacy or outcome of hcv therapy
    Publication number: 20070166702
    Abstract: The present invention relates to a novel method for predicting likeliness of the outcome or efficacy of an antiviral therapy against Hepatitis C Virus (HCV). This method is based on the detection of antibodies against the proteins NSta and or NS5a in a sample of a patient. This method can be further combined with the detection of viral titers of HCV in a sample of a patient. The method of the invention allows a more reliable identification of a subset of non-responders in an early stage of treatment.
    Type: Application
    Filed: July 18, 2005
    Publication date: July 19, 2007
    Inventors: Geert Leroux-Roels, Isabelle Desombere
  • Immunodominant human T-cell epitopes of hepatitis C virus
    Publication number: 20040047877
    Abstract: The present invention relates to a polypeptide of about 8 to about 100 amino acids comprising or consisting of at least 8 contiguous amino acids selected from the core, and/or the E1, and/or E2, and/or the NS3 regions of the HCV polyprotein, with said contiguous amino acids containing a T-ell stimulating epitope.
    Type: Application
    Filed: August 29, 2003
    Publication date: March 11, 2004
    Applicant: Innogenetics
    Inventors: Geert Leroux-Roels, Robert Deleys, Geert Maertens
  • Immunodominant human T-cell epitopes of hepatitis C virus
    Patent number: 6689368
    Abstract: The present invention relates to a polypeptide of about 8 to about 100 amino acids comprising or consisting of at least 8 contiguous amino acids selected from the core, and/or the NS3 regions of the HCV polyprotein, with said contiguous amino acids containing a T-cell stimulating epitope.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: February 10, 2004
    Assignee: Innogenetics N.V.
    Inventors: Geert Leroux-Roels, Robert Deleys, Geert Maertens
  • Immunodominant human T-cell epitopes of hepatitis C virus
    Patent number: 6613333
    Abstract: The present invention relates to a polypeptide of about 8 to about 100 amino acids comprising or consisting of at least 8 contiguous amino acids selected from the core, and/or the NS3 regions of the HCV polyprotein, with said contiguous amino acids containing a T-cell stimulating epitope.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: September 2, 2003
    Assignee: Innogenetics N.V.
    Inventors: Geert Leroux-Roels, Robert Deleys, Geert Maertens
  • Interaction between cd14 and hbv components
    Publication number: 20030152576
    Abstract: The present invention is based on the finding that HBV components (HBsAg) binds to CD14. LPS binding protein catalyses the attachment of HBsAg to CD14. The invention more particularly describes molecules having HBV receptor activity. The invention further describes molecules and compounds for preventing, treating or alleviating inflammatory reactions in patients. The invention also relates to new compounds directed against HBV infections, and methods for identifying them, including in vitro and in vivo model systems to do so. The invention further relates to new vaccine compositions directed against HBV. Additionally the invention also relates to the use of HBV components to treat inflammatory diseases.
    Type: Application
    Filed: September 27, 2002
    Publication date: August 14, 2003
    Inventors: Geert Leroux-Roels, Peter Van Landschoot
  • Immunodominant human T-cell epitopes of hepatitis C virus
    Patent number: 6555114
    Abstract: The present invention relates to a polypeptide of about 8 to about 100 amino acids containing at least about 8 contiguous amino acids selected from the core, and/or the E1, and/or E2, and/or the NS3 regions of the HCV polyprotein, with the contiguous amino acids containing a T-cell stimulating epitope.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: April 29, 2003
    Assignee: Innogenetics N.V.
    Inventors: Geert Leroux-Roels, Robert Deleys, Goort Maertens