Patents by Inventor Geert Maria Robert Van Hecke

Geert Maria Robert Van Hecke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100152277
    Abstract: The present invention generally provides a method of measuring the biological activity of diacylglycerol acyltransferase (DGAT). Specifically, the present invention provides a method for rapid, mass screening of compounds which are able to modulate the biological activity of DGAT. More specifically, the present invention provides an assay system for measuring DGAT activity based on the use of particular micelles with the FlashPlate™ technology.
    Type: Application
    Filed: December 13, 2005
    Publication date: June 17, 2010
    Inventors: Katharina Antonia Germania Josepha Maurita De Waepenaert, Daniëlle Celine Georgette Peeters, Geert Maria Robert Van Hecke, Peter Guido Ida Vermeulen, Monique Jenny Marie Berwaer
  • Publication number: 20080194656
    Abstract: The present invention relates to a group of benzotriazole derivatives, infra that are potent cannabinoid-CB1 modulators (known as antagonists or inverse agonists), useful in the treatment obesity, psychiatric and neurological disorders, as well as other diseases involving cannabinoid-CB1 neurotransmission (Current Opinion in Drug Discovery & Development 2004 7(4):498-506) the pharmaceutically acceptable acid addition salts and stereoisomeric forms thereof, wherein R1 is hydrogen, halo, trifluoromethyl, C1-4alkyl, C1-4alkyloxy- or C1-4alkyloxycarbonyl; R2 is hydrogen, phenyl, C3-7cycloalkyl or C1-6alkyl optionally substituted with Ar1; R3 is hydrogen, hydroxyl or C1-6alkyl; Ar1 is phenyl or phenyl substituted with up to three halo substituents; and Het represents a monocyclic 5 or 6 membered partially saturated or aromatic heterocycle selected from furanyl, thienyl, pyrrolyl, oxazolyl, thiazolyl, imidazolyl, pyrazolyl, isoxazolyl, isothiazolyl, oxadiazolyl, triazolyl, thiadiazolyl, pyrimidinyl, pyrid
    Type: Application
    Filed: April 24, 2006
    Publication date: August 14, 2008
    Inventors: Monique Jenny Marie Berwaer, Joannes Theodorus Maria Linders, Peter John King, Geert Maria Robert Van Hecke