Patents by Inventor Geertje van Mierlo

Geertje van Mierlo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Induction of anti-tumor ctl immunity through in vivo triggering of 4-1bb and/or cd40
    Publication number: 20050255106
    Abstract: Disclosed is a method and composition for treating tumors or infectious diseases, wherein the composition comprises an agonistic anti-CD40 antibody or a fragment thereof, and/or an agonistic anti-4-1BB antibody or a fragment thereof. The agonistic antibody molecules include fragments like Fab, (Fab?)2 and Fv. The methods and compositions may further comprise polypeptides or nucleic acid sequences having or encoding a class 1 MHC or class II MHC-resisted T cell epitope.
    Type: Application
    Filed: April 4, 2003
    Publication date: November 17, 2005
    Inventors: Linda Diehl, Geertje Van Mierlo, Cornelis Melief, Rene Toes, Rienk Offringa
  • Induction of anti-tumor CTL immunity through in vivo triggering of 4-1BB and/or CD40
    Publication number: 20030118588
    Abstract: Disclosed is a method and composition for treating tumors or infectious diseases, wherein the composition comprises an agonist anti-CD40 antibody or a fragment thereof. The anti-CD40 antibody molecules include fragments like Fab, (Fab′)2 and Fv. The composition can also include an agonistic anti-4-1BB antibody or fragment thereof.
    Type: Application
    Filed: April 4, 2002
    Publication date: June 26, 2003
    Inventors: Linda Diehl, Geertje van Mierlo, Robert S. Mittler, Cornelis J.M. Melief, Rene Toes, Rienk Offringa