Abstract: Disclosed herein are methods and systems for filtering entity profiles. A method includes receiving, from a plurality of data sources and for a plurality of medical entities, clinical data and online interaction data; generating a plurality of entity profiles for the plurality medical entities; calculating one or more clinical metrics and one or more online interaction metrics for the plurality of entity profiles from the clinical data and the online interaction data; executing a model using identifications of the plurality of entity profiles and the one or more clinical metrics and the one or more online interaction metrics as input to generate influence scores for the plurality of entity profiles; selecting a subset of the plurality of entity profiles responsive to each entity profile of the subset having an influence score satisfying a selection criteria; and generating a record comprising identifications of the subset of the plurality of entity profiles.

Abstract: Disclosed herein are methods and systems for implementing a multi-model computer architecture for entity identification. A method includes receiving data regarding a plurality of entities. The method includes generating a plurality of entity profiles for the plurality entities and a network graph data structure (e.g., a node graph) comprising edges between nodes for the plurality of entity profiles. The method includes executing a model using identifiers of the plurality of entity profiles, an event topic, and the edges between the nodes as input to generate one or more composite scores for the plurality of entity profiles. The method includes selecting one or more entities for the event based on the generated one or more composite scores. The method includes generating a record comprising associations between identifications of the entities and the event.

Abstract: Flavonol compounds, pharmaceutical compositions of the compounds and methods for treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.

Abstract: The present invention provides a flavonol compound and a bioactive extract/fraction from Ulmus wallichiana useful for the management or prevention or treatment of bone disorders. Said extract/fraction comprising marker compounds of general formula 2, K058: R1?R2?OH K012: R1?R2?OH, 2,3 double bond K068: R1?R2?H KIOOi R1?OH, R2?H mula 2 Wherein the marker compounds K012, K058, K068, K1OO ranges 6.7-12%, 1.7-4.5%, 0.6-1.2%, 1.7-4.5% respectively in alcoholic extract and a process of extraction thereof. According to another aspect of the invention provides a pharmaceutical composition comprising the said compound. The present invention further provides a method of treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.

Abstract: The present invention provides a flavonol compound and a bioactive extract/fraction from Ulmus wallichiana useful for the management or prevention or treatment of bone disorders. Said extract/fraction comprising marker compounds of general formula 2, K058: R1?R2?0H K012: R1?R2?OH, 2,3 double bond K068: R1?R2?H KIOOi R1?OH, R2?H mula 2 Wherein the marker compounds K012, K058, K068, K100 ranges 6.7-12%, 1.7-4.5%, 0.6-1.2%, 1.7-4.5% respectively in alcoholic extract and a process of extraction thereof. According to another aspect of the invention provides a pharmaceutical composition comprising the said compound. The present invention further provides a method of treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.