Abstract: Disclosed are novel protective compositions for dermal papilla cells. In an embodiment the protective compositions of the present invention comprise 0.25% w/w or above of compositions comprising at least 10% w/w and above of 1-O-galloyl-?-D-glucose (?-glucogallin). In an embodiment, the said protective composition additionally comprises 50% to greater than 50% gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid. In another embodiment the invention also encompasses synergistic protective compositions comprising the said protective compositions and 0.5% concentrate of liquid endosperm of Cocos nucifera, for dermal papilla directed towards helping the dermal papilla cells to form sufficient numbers and to retain a healthy morphology conducive for hair growth.

Abstract: Disclosed are novel protective compositions for dermal papilla cells. In an embodiment the protective compositions of the present invention comprise 0.25% w/w or above of compositions comprising at least 10% w/w and above of 1-O-galloyl-?-D-glucose (?-glucogallin). In an embodiment, the said protective composition additionally comprises 50% to greater than 50% gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid. In another embodiment the invention also encompasses synergistic protective compositions comprising the said protective compositions and 0.5% concentrate of liquid endosperm of Cocos nucifera, for dermal papilla directed towards helping the dermal papilla cells to form sufficient numbers and to retain a healthy morphology conducive for hair growth.

Abstract: Disclosed is the cosmeceutical potential of 3,5-dimethoxy-4?-hydroxystilbene in terms of its melanogenesis inhibitory and photo protective activities. Also disclosed does a topical melanogenesis inhibitory composition comprising 0.01 to 50% by weight of 3,5-dimethoxy-4?-hydroxystilbene.

Abstract: Disclosed is a simple method of determining SPF based on the staining pattern of viable cells like mouse fibroblasts and human keratinocytes after exposure to ultraviolet radiations. The method provides results comparable to the standard methods of SPF measurement using human subjects.

Abstract: Disclosed are novel, synthetic analogues of (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione and the therapeutic applications for cystic fibrosis thereof in correcting altered CFTR trafficking and the associated impaired chloride (Cl?) ion transport. Introduction of branched-alkyl groups ortho to the phenolic groups gave rise to clinical compounds with vastly improved trafficking of delF508CFTR and with no cytotoxicity.

Abstract: Disclosed are (i) a standardized method for the recovery of the polyphenolic contents from the seed coats of Tamarindus indica L. (ii) a standardized polyphenolic extract (10%-90%) from the seed coat of Tamarindus indica L. (standardized Indian date extract) and uses thereof as oral/topical, “skin care” and “hair care” nutra-cosmetic formulations. The standardized Indian Date extract of the present invention exhibits anti-collagenase, anti-elastase, anti-5-alpha-reductase and anti-hyaluronidase activities. The standardized Indian date extract of the present invention is suitable for oral/topical, “skin care” and “hair care” nutra-cosmetic formulations either singly or as “cosmetic blends” with other carefully chosen natural plant actives.

Abstract: The present invention discloses the cosmetic applications of alkylalkanols collectively referred to as policosanol, for control of sebum secretion, as anti-acne component and as emollient.