Patents by Inventor Gemma Limones Lopez

Gemma Limones Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing stabilized reaction mixtures which are partially dried, comprising at least one enzyme, reaction mixtures and kits containing said mixtures
    Patent number: 7919294
    Abstract: The invention relates to a method consisting of bringing into contact, in one container, (a) an aqueous solution of a reaction mixture comprising at least one enzyme, and (b) an aqueous solution of a stabilizing mixture comprising (i) at least one protective agent against drying, (ii) at least one inhibitor of the condensation reaction between carbonyl or carboxyl groups and amine or phosphate groups, and (iii) at least one inert polymer capable of generating a mesh structure preventing the mobility of the dried reagents. The invention also consists of removing all or part of the water contained in the resulting aqueous solution. Said process is suitable for carrying out enzymatic reactions, for example, amplifying, sequencing and characterizing nucleic acids, performing hybridization tests and for the restriction analysis.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: April 5, 2011
    Assignee: Biotools Biotechnological & Medical Laboratories, S.A.
    Inventors: Pedro Manuel Franco De Sarabia Rosado, Gemma Limones Lopez, Antonio Madejon Seiz, Maria Dolores Marin Alberdi
  • Nucleic Acid Detection Method Involving the Direct Generation of a Measurable Signal
    Publication number: 20070292868
    Abstract: A nucleic acid detection method involving the direct generation of a measurable signal, by the action of an enzyme with 3?-5? nuclease activity, and the applications for it, the signal generated can be detectable and quantifiable and can be carried out in real-time, in this method, the nucleic acid is placed in contact with at least one oligonucleotide that does not hybridize perfectly with it, so that the enzyme will split it at the unpaired bases generating the signal, the oligonucleotide can be labeled.
    Type: Application
    Filed: June 16, 2005
    Publication date: December 20, 2007
    Applicant: BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A.
    Inventors: Antonio Madejon Seiz, Francisco Calvo Macarro, Pedro Franco De Sarabia Rosado, Gemma Limones Lopez, Sonia Rodriguez Gil
  • Process for preparing stabilized reaction mixtures which are totally or partially dried, comprising at least one enzyme, reaction mixtures and kits containing said mixtures
    Publication number: 20030119042
    Abstract: The invention relates to a method consisting of bringing into contact, in one container, (a) an aqueous solution of a reaction mixture comprising at least one enzyme, and (b) an aqueous solution of a stabilizing mixture comprising (i) at least one protective agent against drying, (ii) at least one inhibitor of the condensation reaction between carbonyl or carboxyl groups and amine or phosphate groups, and (iii) at least one inert polymer capable of generating a mesh structure preventing the mobility of the dried reagents. The invention also consists of removing all or part of the water contained in the resulting aqueous solution. Said process is suitable for carrying out enzymatic reactions, for example, amplifying, sequencing and characterizing nucleic acids, performing hybridization tests and for the restriction analysis.
    Type: Application
    Filed: November 12, 2002
    Publication date: June 26, 2003
    Applicant: Biotools Biotechnological & Medical Laboratories, S.A.
    Inventors: Pedro Manuel Franco De Sarabia Rosado, Gemma Limones Lopez, Antonio Madejon Seiz, Maria Dolores Marin Alberdi