Abstract: To provide a novel compound or a salt thereof or a solvate thereof, having a CSF-1R inhibitory activity and exhibiting antitumor effect. An azaindole derivative of formula (I): wherein A represents a C6-10 aryl ring, an aromatic heterocycle, or an unsaturated heterocycle, and A optionally has one substituent or more same or different substituents; and R represents a C1-3 alkyl group or a saturated heterocyclic group, or a salt thereof or a solvate thereof.

Abstract: Disclosed is a compound which has a low molecular weight and has an activity of enhancing the production of EPO and/or an activity of enhancing the production of hemoglobin.

Abstract: Disclosed is a compound which has a low molecular weight and has an activity of enhancing the production of EPO and/or an activity of enhancing the production of hemoglobin.

Abstract: Disclosed is a compound which has a low molecular weight and has an activity of enhancing the production of EPO and/or an activity of enhancing the production of hemoglobin.

Abstract: The present invention relates to provision of a novel compound that has an activity of promoting insulin secretion from pancreatic ? cells and thus is useful as a prophylaxis and/or therapeutic agent for diseases caused by hyperglycemia such as diabetes mellitus, and the compound represented by the following formula (1): wherein one of A and B represents a nitrogen atom and the other represents a nitrogen atom or CR10, X represents an oxygen atom, a sulfur atom or —(CH2)n-N(R12)—, Y represents an oxygen atom, a sulfur atom or —N(R13)—, and R1 to R9 each represent a hydrogen atom or another substituent, or a salt thereof, or a solvate of the compound or the salt.

Abstract: Disclosed is a compound which has both an angiotensin-II receptor antagonistic activity and a PPAR? activation activity and is useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, angina pectoris, cerebrovascular disorders, cerebral circulatory disorders, ischemic peripheral circulatory disorders, renal diseases, arteriosclerosis, inflammatory diseases, type-2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinemia. [In the formula, A represents a 5- to 10-membered heteroaryl group; R1 and R2 independently represent a C1-6 alkyl group; and each of R3 to R5 is absent or represents H, a halogen atom, OH, NO2, a halo-C1-6 alkyl group, a (substituted) C1-6 alkoxy group, a (substituted) C3-6 cycloalkyloxy group, or a 5- to 10-membered heteroaryl group.

Abstract: The present invention relates to provision of a novel compound that has an activity of promoting insulin secretion from pancreatic ? cells and thus is useful as a prophylaxis and/or therapeutic agent for diseases caused by hyperglycemia such as diabetes mellitus, and the compound represented by the following formula (1): wherein one of A and B represents a nitrogen atom and the other represents a nitrogen atom or CR10, X represents an oxygen atom, a sulfur atom or —(CH2)n-N(R12)—, Y represents an oxygen atom, a sulfur atom or —N(R13)—, and R1 to R9 each represent a hydrogen atom or another substituent, or a salt thereof, or a solvate of the compound or the salt.

Abstract: Disclosed is novel compound and medicinal formulation containing same, possessing both angiotensin II receptor blocking and PPAR? activation effect, of use as a medicine for prevention and/or treatment of hypertension, heart disease, angina pectoris, cerebrovascular disorder, cerebral circulatory disturbances, post-ischemic peripheral circulatory damage, renal disease, arteriosclerosis, inflammatory disorder, type 2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinaemia. Further disclosed is the general formula I (where one or both of R1 and R2 represent a C1-6 alkyl group, R3 represents a C1-6 alkyl group which may contain one or more substituent groups selected from group A, or a C3-8 cycloalkyl group which may contain one or more substituent groups selected from group B.) which represents the compound, and salts thereof, solvates thereof, and medicinal compositions containing any of these.

Abstract: According to one embodiment, a control module determines whether a second authentication key is present in a authentication key storage device when an information processing apparatus is powered on. The control module displays an identification code input screen for inputting an identification code if the second authentication key is not present, causes a storage device to execute an identification code authentication process of determining whether the identification code which is input to the identification code input screen agrees with the first identification code, and generates a third authentication key and stores the third authentication key in the authentication key storage device if the identification code authentication process is successfully carried out.

Abstract: Disclosed is a novel 1-(biphenyl-4-yl-methyl)-1H-imidazole derivative represented by general formula (I), which has both angiotensin II receptor antagonist activity and PPAR-? activating activity and is useful as a prophylactic and/or therapeutic agent for cardiovascular diseases and metabolic diseases. Also disclosed is a pharmaceutical composition which contains the novel 1-(biphenyl-4-yl-methyl)-1H-imidazole derivative. In general formula (I), ring A represents a group represented by formula (II) or (III); R1 represents a C1-6 alkyl group; R2 represents a C1-6 alkyl group which may be substituted by a hydroxy group, or a group represented by formula —CO—R4 (wherein R4 represents a hydroxy group, a C1-6 alkoxy group, an amino group, a mono(C1-6 alkyl)amino group, a di(C1-6 alkyl)amino group, a morpholino group, a piperidino group or a pyrrolidino group); R3 represents a halogen atom or a C1-6 alkoxy group; and X and Y may be the same or different and each represents a nitrogen atom or CH.

Abstract: An ?-phenoxybenzeneacetic acid derivative represented by general formula (I), which has both an angiotensin II receptor antagonistic activity and a PPAR? activation activity and is useful as a prophylactic and/or therapeutic agent for hypertension, metabolic syndrome or the like, a salt of the derivative, or a solvate of the derivative or the salt; and a pharmaceutical composition containing the derivative, the salt or the solvate.

Abstract: Disclosed is a compound which has both an angiotensin-II receptor antagonistic activity and a PPAR? activation activity and is useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, angina pectoris, cerebrovascular disorders, cerebral circulatory disorders, ischemic peripheral circulatory disorders, renal diseases, arteriosclerosis, inflammatory diseases, type-2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinemia. [In the formula, A represents a 5- to 10-membered heteroaryl group; R1 and R2 independently represent a C1-6 alkyl group; and each of R3 to R5 is absent or represents H, a halogen atom, OH, NO2, a halo-C1-6 alkyl group, a (substituted) C1-6 alkoxy group, a (substituted) C3-6 cycloalkyloxy group, or a 5- to 10-membered heteroaryl group.

Abstract: Disclosed is a compound which has a low molecular weight and has an activity of enhancing the production of EPO and/or an activity of enhancing the production of hemoglobin.

Abstract: Provided are novel compounds that have both angiotensin II receptor-antagonist effects and PPAR-activating effects that are useful as agents for preventing and/or treating hypertension, heart disease, angina, cerebral vascular accident, cerebrovascular disorder, ischemic peripheral circulatory disorder, kidney disease, atherosclerosis, inflammatory disease, type 2 diabetes mellitus, diabetic complication, insulin resistance syndrome, Syndrome X, metabolic syndrome, and hyperinsulinemia.

Abstract: According to one embodiment, an electronic apparatus includes a display, an operating module, a power saving module, a sensor and a controller. The power saving module is configured to turn off a screen of the display when a non-operating period of the operating module reaches a reference period. The sensor is configured to detect a vibration. The controller is configured to change the reference period from a first value given as the initial value to a second value longer than the first value when the sensor detects a vibration.

Abstract: According to one embodiment, an information processing apparatus includes a processor including a register file which holds physical registers to which general purpose registers provided by an instruction set architecture are assigned, a virtual register assigning unit which assigns a virtual address in the main memory space to a physical register in the register file based on a request from a program, and records a correspondence between each of the virtual addresses and a corresponding one of the physical registers in a virtual register conversion table, and an access converting unit which determines whether or not a virtual address to be accessed is recorded in the virtual register conversion table managed by the virtual register assigning unit, and executes, when the virtual address is recorded therein, processing of accessing the physical register of which a correspondence to the virtual address is recorded in the virtual register conversion table.

Abstract: According to one embodiment, an electronic apparatus includes a reader, a setting module, a determination module, and a processing module. The reader configured to read first and second data from first and second recording medium. The setting module configured to set function setup data in which the first data, which is read from the first recording medium by the reader, is associated with data indicative of content of a process. The determination module configured to determine whether the second data, which is read from the second recording medium by the reader, agrees with the first data. The processing module configured to perform a process, based on the data which is indicative of the content of the process and is associated with the first data, when the determination module determines that the second data agrees with the first data.

Abstract: According to one embodiment, an information processing apparatus includes a first caching processing module which starts a caching moving image data stored in a storage medium in a memory device when the storage medium is loaded in a media drive, and a second caching processing module which erases all of moving image data items cached in the memory device when the storage medium is ejected from the media drive.

Abstract: According to one embodiment, an electronic device includes a communication module, an electrical field strength detector, a state detector, an output module, and an output controller. The communication module transmits and receives a radio signal. The electrical field strength detector detects electrical field strength of the radio signal transmitted and received by the communication module. The state detector detects a first state where the electrical field strength detected by the electrical field strength detector increases with the lapse of time and a second state where the electrical field strength detected by the electrical field strength detector decreases with the lapse of time. The output controller controls output from the output module based on the first state and the second state.

Abstract: According to one embodiment, an information processing apparatus includes a power supply module, a connection bus, a processor connected to the connection bus and including a power supply control circuit module supplied with power from the power supply module and a arithmetic circuit module connected to the power supply control circuit module, a power supply control module configured to control supply of power from the power supply module to the arithmetic circuit module of the processor, and control module for sending, when the power supply control circuit module of the processor receives a predetermined notification, the predetermined notification to the power supply control module from the power supply control circuit module, and controlling, by the power supply control module which has received the predetermined notification, to stop power supply from the power supply module to the arithmetic circuit module.