Patents by Inventor Gene Dubowchik

Gene Dubowchik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-MIGRAINE TREATMENTS
    Publication number: 20070232600
    Abstract: The present invention relates to methods of treating neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors using pharmaceutical compositions comprising compounds of Formula (I)
    Type: Application
    Filed: January 5, 2007
    Publication date: October 4, 2007
    Inventors: Ling Chen, Prasad Chaturvedula, Rita Civiello, Andrew Degnan, Gene Dubowchik, Xiaojun Han, Xiang Jun Jiang, George Karageorge, Guanglin Luo, John Macor, Graham Poindexter, George Tora
  • ANTI-MIGRAINE SPIROCYCLES
    Publication number: 20070149503
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Application
    Filed: January 5, 2007
    Publication date: June 28, 2007
    Inventors: PRASAD CHATURVEDULA, Ling Chen, Rita Civiello, Andrew Degnan, Gene Dubowchik, Xiaojun Han, Xiang Jun Jiang, John Macor, Graham Poindexter, George Tora, Guanglin Luo
  • SPIROCYCLIC ANTI-MIGRAINE COMPOUNDS
    Publication number: 20070149502
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Application
    Filed: January 5, 2007
    Publication date: June 28, 2007
    Inventors: Prasad Chaturvedula, Gene Dubowchik, Xiang Jun Jiang, John Macor, Graham Poindexter, Shikha Vig
  • Novel therapeutic agents for the treatment of migraine
    Publication number: 20050215576
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Application
    Filed: March 28, 2005
    Publication date: September 29, 2005
    Inventors: Andrew Degnan, Xiaojun Han, Gene Dubowchik, John Macor, Stephen Mercer
  • Heterocyclic anti-migraine agents
    Publication number: 20050153959
    Abstract: The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
    Type: Application
    Filed: December 3, 2004
    Publication date: July 14, 2005
    Inventors: Guanglin Luo, Ling Chen, Andrew Degnan, Gene Dubowchik, John Macor, George Tora, Prasad Chaturvedula