Patents by Inventor Gene G. Olinger

Gene G. Olinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MODELING IN VIVO EFFICACY OF DRUG COMBINATIONS FOR TREATMENT OF VIRAL INFECTIONS
    Publication number: 20240127967
    Abstract: Methods of modeling the in vivo efficacy of drug combinations for the treatment or prevention of viral infection are described. The described methods combine data for single drugs and drug combinations from pharmacokinetic, pharmacodynamic, and viral dynamics models under a series of estimated in vivo drug potencies to provide predictions of the in vivo effects of the drug combinations. These predictions can be used to more accurately select drugs and drug treatment regimens that can be successful in controlling viral infection in animal studies, clinical trials and in medical or veterinary interventions. Also described is a method of treating or preventing filovirus infections using combinations of orally available drugs based on predictions from the modeling methods.
    Type: Application
    Filed: February 9, 2022
    Publication date: April 18, 2024
    Applicants: University of Virginia Patent Foundation, Fred Hutchinson Cancer Research Center
    Inventors: Judith M. White, Shuang Xu, Joshua T. Schiffer, Gene G. Olinger, Courtney L. Finch, Julie Dyall, Stephen J. Polyak, Lisa Johansen
  • COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES
    Publication number: 20130289024
    Abstract: The invention features compositions, methods, and kits useful for the treatment of filovirus-mediated diseases, e.g., hemorrhagic fever caused by Ebola virus, in an animal.
    Type: Application
    Filed: June 27, 2013
    Publication date: October 31, 2013
    Inventors: Lisa M. JOHANSEN, Joseph LEHÁR, Benjamin G. HOFFSTROM, Gene G. OLINGER, Andrea R. STOSSEL
  • Compositions and methods for treatment of filovirus-mediated diseases
    Patent number: 8475804
    Abstract: The invention features compositions, methods, and kits useful for the treatment of filovirus-mediated diseases, e.g., hemorrhagic fever caused by Ebola virus, in an animal.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: July 2, 2013
    Assignees: U.S. Army Medical Research and Material Command, Zalicus, Inc.
    Inventors: Lisa M. Johansen, Joseph Lehár, Benjamin G. Hoffstrom, Gene G. Olinger, Andrea R. Stossel
  • COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES
    Publication number: 20110028564
    Abstract: The invention features compositions, methods, and kits useful for the treatment of filovirus-mediated diseases, e.g., hemorrhagic fever caused by Ebola virus, in an animal.
    Type: Application
    Filed: February 22, 2010
    Publication date: February 3, 2011
    Inventors: Lisa M. Johansen, Joseph Lehár, Benjamin G. Hoffstrom, Gene G. Olinger, Andrea R. Stossel