Abstract: An implantable surgical mesh is provided, one embodiment of which includes a plurality of absorbable filaments, and a plurality of non-absorbable filaments. Substantially all of the plurality of non-absorbable filaments are substantially aligned in a single direction with substantially no cross-linking therebetween. The plurality of absorbable filaments are interwoven with the non-absorbable filaments to thereby form a bi-directional mesh structure prior to absorption of the absorbable filaments.

Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.

Abstract: A surgical instrument for dissecting tissue and inserting a surgical implant device thereat includes first and second blades which are pivotally joined together. Each of the first and second blades has an elongated length which includes a first section and a second section, the first section of each blade including a free end having a flattened tip for blunt dissection of tissue and a non-cutting, clamping portion situated adjacent to and encompassing the flattened tip for selectively grasping a surgical implant device. The second section of each blade includes a finger ring for grasping and manipulation by a surgeon. The blades are pivotally joined together at the junctures of the first and second sections to allow the first and second blades to pivotally move with respect to one another within a plane of pivotal movement.

Abstract: Various surgical assemblies are provided, one embodiment of which includes a substantially flat template having first and second opposed sides, and having a plurality of graduated markings on said first side, and a substantially flat, flexible, surgical implant removably secured to the template and having first and second substantially flat opposed sides, and at least a first trimable portion. The surgical implant is removably coupled to the template so that the first side of the template is substantially adjacent to the first side of the surgical mesh, and so that the plurality of graduated markings are substantially adjacent to the first trimable portion of the surgical implant.

Abstract: The present invention is a method and device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The closure device includes a closure line having a first and a second end. A first expandable device is connected to the first end of the closure line. A second expandable device is located along the second end of the closure line, and is capable of sliding along the closure line in one direction while preventing sliding movement in the opposite direction. Alternatively the second closure line is fixed along the second end of the closure line.

Abstract: A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The deployment device has a first tubular structure having proximal and distal ends. A second tubular structure is substantially coaxial to and slideably engaged within the first tubular structure. The second tubular structure has a first substantially linear shape when constrained within the first tubular structure, and a second curvilinear shape when telescopically extended from the distal end of the first tubular structure. A third tubular structure is substantially coaxial to and slideably engaged within the second tubular structure. The third tubular structure is configured to provide sufficient rigidity to push the mechanical closure device from the distal end of the second tubular structure, and provide sufficient flexibility to assume a curvilinear shape when deflected by the second tubular structure.

Abstract: The present invention relates to a delivery system for delivering a device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The delivery system has an elongate member having a proximal and distal end. A deflectable needle assembly having luminal and abluminal surfaces is slideably engaged within the elongate member. An actuator is slideabley engaged within the elongate member and attached to the needle tip assembly such that translational movement of the actuator causes deflection of the deflectable needle assembly.

Abstract: A system for holding surgical fasteners each having a first anchor, a second anchor and a connector extending therebetween upwardly from the first and second anchors, and a method for loading the same into an applicator. The system includes a shuttle having first and second channels dimensioned to slidably receive therein the first and second anchors, and having first and second grooves respectively forming openings into the channels along a portion of a length of the channels. When the first and second anchors are received within the first and second channels, the connector of the surgical fastener extends out of the shuttle through the first and second grooves. The system also includes a cartridge having at least a first channel dimensioned to slidably receive the shuttle therein, and having a first projection extending into the first channel.

Abstract: A system and method for placing surgical implants and having particular application for pelvic floor repair. The system includes an assembly having a guide element with a tissue penetrating tip, a cannula, and a retrieval device having a capture element at its distal end. A channel in the cannula is dimensioned to allow passage therethrough of the guide element, and of the retrieval element when removably coupled with an extension of the surgical implant.

Abstract: An applicator for deploying a fastener having two legs into tissue. The applicator has two elongated hollow needle members, slotted portions at the distal ends of the hollow needle members for releasably retaining the legs of the fastener, two push rods adapted to move lengthwise in the two needle members, and an actuator for moving the two push rods in the needle members so as to eject the leg portions of the fastener from the slotted portion of the two needle members. A method for deploying the fastener in tissue is also disclosed.

Abstract: A fastener for surgical repair of tissue is provided along with methods for its use. The fastener includes first and second anchors and a connector including a first central biasing section coupled to the first anchor and a second central biasing section having coupled to the second anchor, and a connector section extending between the other ends of the first and second central biasing sections. The first and second central biasing sections are capable of being elastically deformed from a first relaxed resting position to a second extended position wherein the connector section is positioned a further distance away from and is biased toward the anchors.

Abstract: A urethra support having an elongated mesh tape portion and a mesh extension affixed to the tape portion transverse thereto. In accordance with a method of the invention, the urethra support is inserted into the lower pelvic cavity of a patient with the tape portion forming a sling extending beneath and supporting the urethra of the patient. In this position, the tape portion is generally perpendicular to the urethra. The extension is inserted into the peri-urethral fascia along at least a portion of the length of the urethra. This induces the formation of scar tissue proximate the extension, with the scar tissue eventually contracting thereby compressing the urethra.

Abstract: An intracorporeal knot tying device. The knot tying device comprises a cannula tube having a proximal end and a distal end and passage therethrough. A suture is movably mounted within the tubular passage. A needle is mounted to the distal end of the suture. The cannula has in its distal end a slit or a distally extending arm for retaining the suture and maneuvering the suture while tying an intracorporeal knot.

Abstract: A medical device for ligation or approximating tissue is disclosed. The device has a cannula with proximal and distal ends. The distal end of the cannula has a beveled surface, and the cannula has first and second channels, the first channel extending axially through it, and the second channel extending from the beveled surface to the first channel. The device includes a suture with a slide end and a distal loop, as well as a slip knot securing the loop to the slide end. The slide end is threaded thorough the first and second channels of the cannula and it protrudes from the proximal end of the cannula. In addition, the device incorporates means for securing the positioning of the slide end of the suture in the first channel of the cannula. The device may optionally have a frangible proximal end wherein the proximal end of the suture is mounted to the frangible proximal end.