Patents by Inventor Gene Kopen

Gene Kopen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140099329
    Abstract: The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: August 19, 2013
    Publication date: April 10, 2014
    Applicant: Garnet BioTherapeutics, Inc.
    Inventors: GENE KOPEN, Joseph Wagner, Vanessa Ragaglia, Baron Heimbach, Richard S. Gore
  • Publication number: 20140086884
    Abstract: The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: August 19, 2013
    Publication date: March 27, 2014
    Applicant: Gamet BioTherapeutics, Inc.,
    Inventors: GENE KOPEN, Joseph Wagner, Vanessa Ragaglia, Baron Heimbach, Richard S. Gore
  • Publication number: 20130266542
    Abstract: The invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: March 12, 2013
    Publication date: October 10, 2013
    Applicant: Garnet BioThereapeutics, Inc.
    Inventors: Gene KOPEN, Vanessa RAGAGLIA, Candace BRAYFIELD
  • Publication number: 20130259837
    Abstract: The invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: March 12, 2013
    Publication date: October 3, 2013
    Inventors: Gene KOPEN, Vanessa RAGAGLIA, Candace BRAYFIELD
  • Patent number: 8354370
    Abstract: The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Grant
    Filed: June 16, 2008
    Date of Patent: January 15, 2013
    Assignee: Garnet BioTherapeutics, Inc.
    Inventors: Gene Kopen, Joseph Wagner, Vanessa Ragaglia, Baron Heimbach, Richard S. Gore
  • Publication number: 20120156192
    Abstract: The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: January 12, 2012
    Publication date: June 21, 2012
    Applicant: Garnet Biotherapeutics, Inc.
    Inventors: Gene KOPEN, Joseph WAGNER, Vanessa RAGAGLIA, Baron HEIMBACH, Richard S. GORE
  • Publication number: 20120148544
    Abstract: The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: January 12, 2012
    Publication date: June 14, 2012
    Applicant: Garnet Biotherapeutics, Inc.
    Inventors: Gene KOPEN, Joseph Wagner, Vanessa Ragaglia, Baron Heimbach, Richard S. Gore
  • Publication number: 20120121555
    Abstract: The invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: January 12, 2012
    Publication date: May 17, 2012
    Applicant: Garnet Biotherapeutics, Inc.
    Inventors: Gene KOPEN, Vanessa Ragaglia, Candace Brayfield
  • Publication number: 20120003188
    Abstract: The invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: May 27, 2011
    Publication date: January 5, 2012
    Applicant: Garnet Biotherapeutics, Inc.
    Inventors: Gene KOPEN, Vanessa RAGAGLIA, Candace BRAYFIELD
  • Publication number: 20090053183
    Abstract: The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.
    Type: Application
    Filed: June 16, 2008
    Publication date: February 26, 2009
    Applicant: Neuronyx Inc.
    Inventors: Gene Kopen, Joseph Wagner, Vanessa Ragaglia, Baron Heimbach, Richard S. Gore
  • Publication number: 20070264232
    Abstract: Substantially homogenous cells populations which co-express CD49c, CD90 and telomerase are made. In one embodiment, humans suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition are treated with the substantially homogenous cells populations which co-express CD49c, CD90 and telomerase. In another embodiment, committed progenitor cells are made are made by selecting from a cultured source of a cell population which co-express CD49c and CD90 and modifying the cell population. The committed progenitor cells can be employed to treat a human suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition and formulate pharmaceutical compositions.
    Type: Application
    Filed: May 2, 2007
    Publication date: November 15, 2007
    Applicant: Neuronyx, Inc.
    Inventors: Tony Ho, Gene Kopen, William Righter, J. Rutkowski, Joseph Wagner
  • Publication number: 20070243609
    Abstract: Substantially homogenous cells populations which co-express CD49c, CD90 and telomerase are made. In one embodiment, humans suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition are treated with the substantially homogenous cells populations which co-express CD49c, CD90 and telomerase. In another embodiment, committed progenitor cells are made are made by selecting from a cultured source of a cell population which co-express CD49c and CD90 and modifying the cell population. The committed progenitor cells can be employed to treat a human suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition and formulate pharmaceutical compositions.
    Type: Application
    Filed: February 7, 2007
    Publication date: October 18, 2007
    Inventors: Tony Ho, Gene Kopen, William Righter, J. Rutkowski, Joseph Wagner
  • Publication number: 20070231309
    Abstract: Substantially homogenous cells populations which co-express CD49c, CD90 and telomerase are made. In one embodiment, humans suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition are treated with the substantially homogenous cells populations which co-express CD49c, CD90 and telomerase. In another embodiment, committed progenitor cells are made are made by selecting from a cultured source of a cell population which co-express CD49c and CD90 and modifying the cell population. The committed progenitor cells can be employed to treat a human suffering from a degenerative, traumatic, acute injury cardiac or neurological condition and formulate pharmaceutical compositions.
    Type: Application
    Filed: March 19, 2007
    Publication date: October 4, 2007
    Applicant: Neuronyx, Inc.
    Inventors: Tony Ho, Gene Kopen, William Righter, J. Rutkowski, Joseph Wagner
  • Publication number: 20070224177
    Abstract: Substantially homogenous cells populations which co-express CD49c, CD90 and telomerase are made. In one embodiment, humans suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition are treated with the substantially homogenous cells populations which co-express CD49c, CD90 and telomerase. In another embodiment, committed progenitor cells are made are made by selecting from a cultured source of a cell population which co-express CD49c and CD90 and modifying the cell population. The committed progenitor cells can be employed to treat a human suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition and to formulate pharmaceutical compositions. In a further embodiment, a substantially homogenous population of cells which co-express CD49c, CD90 and at least one cardiac-related transcription factor is made and can be used to treat a human suffering from a cardiac condition.
    Type: Application
    Filed: February 7, 2007
    Publication date: September 27, 2007
    Inventors: Tony Ho, Gene Kopen, William Righter, J. Rutkowski, Joseph Wagner, W. Herring, Vanessa Ragaglia
  • Publication number: 20050233452
    Abstract: Substantially homogenous cells populations which co-express CD49c, CD90 and telomerase are made. In one embodiment, humans suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition are treated with the substantially homogenous cells populations which co-express CD49c, CD90 and telomerase. In another embodiment, committed progenitor cells are made are made by selecting from a cultured source of a cell population which co-express CD49c and CD90 and modifying the cell population. The committed progenitor cells can be employed to treat a human suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition and formulate pharmaceutical compositions.
    Type: Application
    Filed: February 10, 2005
    Publication date: October 20, 2005
    Applicant: Neuronyx, Inc.
    Inventors: Tony Ho, Gene Kopen, William Righter, J. Rutkowski, Joseph Wagner