Patents by Inventor Genevieve COURTOIS

Genevieve COURTOIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and pharmaceutical compositions for the treatment of beta-thalassemias
    Patent number: 9861615
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of beta-thalassemias. In particular, the present invention relates to an XPO1 inhibitor for use in a method for treating beta-thalassemia in a subject in need thereof.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: January 9, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universite Paris Decartes, Assistance Publique-Hopitaux de Paris (APHP), Fondation Imagine, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Olivier Hermine, Flavia Guillem, Jean-Benoit Arlet, Genevieve Courtois
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BETA-THALASSEMIAS
    Publication number: 20170020847
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of beta-thalassemias. In particular, the present invention relates to an XPO1 inhibitor for use in a method for treating beta-thalassemia in a subject in need thereof.
    Type: Application
    Filed: November 18, 2014
    Publication date: January 26, 2017
    Applicants: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE PARIS DESCARTES, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP), FOUNDATION IMAGINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Olivier HERMINE, Flavia GUILLEM, Jean-Benoit ARLET, Genevieve COURTOIS
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF BETA-THALASSEMIA
    Publication number: 20160368975
    Abstract: Methods and compositions for the treatment of ?-thalassemia are provided. Methods and compositions restore or increase erythrocyte maturation in individuals afflicted with ?-TM by preventing proteolysis of GATA-1 protein. Screening methods for identifying agents which bind heat shock protein 70 (HSP-70) and inhibit HSP-70 ?-globin binding, but which allow GATA-1 protein-HSP-1 binding in a manner that prevents GATA-1 proteolysis.
    Type: Application
    Filed: May 23, 2016
    Publication date: December 22, 2016
    Inventors: Olivier HERMINE, Genevieve COURTOIS, Jean-Benoit ARLET, Jean-Antoine RIBEIL
  • Methods and compositions for the treatment of ?-thalassemia
    Patent number: 9377471
    Abstract: Methods and compositions for the treatment of ?-thalassemia are provided. Methods and compositions restore or increase erythrocyte maturation in individuals afflicted with ?-TM by preventing proteolysis of GATA-1 protein. Screening methods for identifying agents which bind heat shock protein 70 (HSP-70) and inhibit HSP-70 ?-globin binding, but which allow GATA-1 protein-HSP-1 binding in a manner that prevents GATA-1 proteolysis.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: June 28, 2016
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Universite Paris Descartes—Paris V, Assistance Publique—Hopitaux de Paris, Fondation Imagine
    Inventors: Olivier Hermine, Genevieve Courtois, Jean-Benoit Arlet, Jean-Antoine Ribeil
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF BETA-THALASSEMIA
    Publication number: 20150141341
    Abstract: Methods and compositions for the treatment of ?-thalassemia are provided. Methods and compositions restore or increase erythrocyte maturation in individuals afflicted with ?-TM by preventing proteolysis of GATA-1 protein. Screening methods for identifying agents which bind heat shock protein 70 (HSP-70) and inhibit HSP-70 ?-globin binding, but which allow GATA-1 protein-HSP-1 binding in a manner that prevents GATA-1 proteolysis.
    Type: Application
    Filed: November 19, 2014
    Publication date: May 21, 2015
    Inventors: Olivier HERMINE, Genevieve COURTOIS, Jean-Benoit ARLET, Jean-Antoine RIBEIL