Patents by Inventor Genevieve R. Giroux

Genevieve R. Giroux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified xylanase exhibiting improved expression
    Patent number: 7691609
    Abstract: A modified Family 11 xylanase enzyme comprising a sequence that introduces a functional consensus glycosylation site is provided. Non-limiting examples of introduced glycosylation sites include mutation of the amino acid at position 34, 131, 180, 182, or a combination thereof, to an asparagine. The indicated amino acid position in the Family 11 xylanase is determined from sequence alignment of the xylanase of interest with that of a Trichoderma reesei xylanase II amino acid sequence. The introduced consensus glycosylation site facilitates increased expression efficiency of the modified xylanase when compared to the expression efficiency of a corresponding xylanase from which the modified xylanase was derived, using similar host strains and growth conditions.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: April 6, 2010
    Assignee: Iogen Bio-Products Corporation
    Inventors: Theresa C. White, Genevieve R. Giroux, Katie E. A. Wallace
  • MODIFIED XYLANASE EXHIBITING IMPROVED EXPRESSION
    Publication number: 20090111155
    Abstract: A modified Family 11 xylanase enzyme comprising a sequence that introduces a functional consensus glycosylation site is provided. Non-limiting examples of introduced glycosylation sites include mutation of the amino acid at position 34, 131, 180, 182, or a combination thereof, to an asparagine. The indicated amino acid position in the Family 11 xylanase is determined from sequence alignment of the xylanase of interest with that of a Trichoderma reesei xylanase II amino acid sequence. The introduced consensus glycosylation site facilitates increased expression efficiency of the modified xylanase when compared to the expression efficiency of a corresponding xylanase from which the modified xylanase was derived, using similar host strains and growth conditions.
    Type: Application
    Filed: November 7, 2008
    Publication date: April 30, 2009
    Applicant: IOGEN BIO-PRODUCTS CORPORATION
    Inventors: Theresa White, Genevieve R. Giroux, Katie E.A. Wallace
  • Modified xylanases exhibiting improved expression
    Patent number: 7456005
    Abstract: A modified Family 11 xylanase enzyme comprising a sequence that introduces a functional consensus glycosylation site is provided. Non-limiting examples of introduced glycosylation sites include mutation of the amino acid at position 34, 131, 180, 182, or a combination thereof, to an asparagine. The indicated amino acid position in the Family 11 xylanase is determined from sequence alignment of the xylanase of interest with that of a Trichoderma reesei xylanase II amino acid sequence. The introduced consensus glycosylation site facilitates increased expression efficiency of the modified xylanase when compared to the expression efficiency of a corresponding xylanase from which the modified xylanase was derived, using similar host strains and growth conditions.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: November 25, 2008
    Assignee: Iogen Bio-Products Corporation
    Inventors: Theresa White, Genevieve R. Giroux, Katie E. A. Wallace