Patents by Inventor Gengfeng Zheng
Gengfeng Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240028937Abstract: A method for evaluating the health status of a petrochemical atmospheric oil storage tank using data from multiple sources. The health status of an atmospheric oil storage tank is influenced by multiple factors, and is evaluated by: acquiring corresponding sensor data and comprehensively considering the sensor data along with basic data of the oil storage tank, and selecting from a dynamic monitoring parameter-based health status and a basic health status of the oil storage tank, the one having a greater severity level, so as to determine the final health status of the oil storage tank. The method is used to conduct a comprehensive scientific assessment of the health status of an oil storage tank, and improves the use safety of the oil storage tank.Type: ApplicationFiled: March 12, 2021Publication date: January 25, 2024Inventors: Honghua Zhang, Qinda Zeng, Yuanyue Zeng, Gengfeng Zheng, Chunrong Huang, Yao Lin, Ning Lin, Ting Xiao
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Patent number: 10474029Abstract: The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes.Type: GrantFiled: January 25, 2019Date of Patent: November 12, 2019Assignee: NORTHWESTERN UNIVERSITYInventors: Chad A. Mirkin, Fengwei Huo, Zijian Zheng, Gengfeng Zheng
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Publication number: 20190265587Abstract: The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes.Type: ApplicationFiled: January 25, 2019Publication date: August 29, 2019Inventors: Chad A. Mirkin, Fengwei Huo, Zijian Zheng, Gengfeng Zheng
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Patent number: 10222694Abstract: The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes.Type: GrantFiled: May 19, 2016Date of Patent: March 5, 2019Assignee: NORTHWESTERN UNIVERSITYInventors: Chad A. Mirkin, Fengwei Huo, Zijian Zheng, Gengfeng Zheng
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Patent number: 9535063Abstract: One aspect of the invention provides a nanoscale wire that has improved sensitivity, for example, as the carrier concentration in the wire is controlled by an external gate voltage. In one set of embodiments, the nanoscale wire has a Debye screening length that is greater than the average cross-sectional dimension of the nanoscale wire when the nanoscale wire is exposed to a solution suspected of containing an analyte. In certain instances, the Debye screening length associated with the carriers inside nanoscale wire may be adjusted by adjusting the voltage, for example, a gate voltage applied to an FET structure. In some cases, the nanoscale wire can be operated under conditions where the carriers in the nanoscale wire are depleted and the nanoscale wire has a conductance that is not linearly proportional to the voltage applied to the nanoscale wire sensor device, for example, via a gate electrode.Type: GrantFiled: September 18, 2013Date of Patent: January 3, 2017Assignee: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Xuan Gao, Gengfeng Zheng
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Publication number: 20160357101Abstract: The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes.Type: ApplicationFiled: May 19, 2016Publication date: December 8, 2016Inventors: Chad A. Mirkin, Fengwei Huo, Zijian Zheng, Gengfeng Zheng
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Patent number: 9372397Abstract: The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes.Type: GrantFiled: April 25, 2009Date of Patent: June 21, 2016Assignee: NORTHWESTERN UNIVERSITYInventors: Chad A. Mirkin, Fengwei Huo, Zijian Zheng, Gengfeng Zheng
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Patent number: 9021611Abstract: The disclosure relates to methods of beam pen lithography using a tip array having a plurality of transparent, elastomeric, reversibly-deformable tips coated with a blocking layer and apertures defined in the blocking layer to expose tip ends of the tips in the array. The tip array can be used to perform a photolithography process in which the tips are illuminated with a radiation that is channeled through the tips and out the apertures to expose a photosensitive substrate. Also disclosed are tip arrays formed of polymers and gels, apparatus including the tip arrays and radiation sources, and related apparatus for selectively masking tips in the tip array from radiation emitted from the radiation source.Type: GrantFiled: February 18, 2010Date of Patent: April 28, 2015Assignee: Northwestern UniversityInventors: Chad A. Mirkin, Gengfeng Zheng, Fengwei Huo
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Patent number: 8961853Abstract: Disclosed are methods of lithography using a tip array having a plurality of pens attached to a backing layer, where the tips can comprise a metal, metalloid, and/or semi-conducting material, and the backing layer can comprise an elastomeric polymer. The tip array can be used to perform a lithography process in which the tips are coated with an ink (e.g., a patterning composition) that is deposited onto a substrate upon contact of the tip with the substrate surface. The tips can be easily leveled onto a substrate and the leveling can be monitored optically by a change in light reflection of the backing layer and/or near the vicinity of the tips upon contact of the tip to the substrate surface.Type: GrantFiled: June 4, 2010Date of Patent: February 24, 2015Assignee: Northwestern UniversityInventors: Chad A. Mirkin, Wooyoung Shim, Adam B. Braunschweig, Xing Liao, Jinan Chai, Jong Kuk Lim, Gengfeng Zheng, Zijian Zheng
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Publication number: 20140080139Abstract: One aspect of the invention provides a nanoscale wire that has improved sensitivity, for example, as the carrier concentration in the wire is controlled by an external gate voltage. In one set of embodiments, the nanoscale wire has a Debye screening length that is greater than the average cross-sectional dimension of the nanoscale wire when the nanoscale wire is exposed to a solution suspected of containing an analyte. In certain instances, the Debye screening length associated with the carriers inside nanoscale wire may be adjusted by adjusting the voltage, for example, a gate voltage applied to an FET structure. In some cases, the nanoscale wire can be operated under conditions where the carriers in the nanoscale wire are depleted and the nanoscale wire has a conductance that is not linearly proportional to the voltage applied to the nanoscale wire sensor device, for example, via a gate electrode.Type: ApplicationFiled: September 18, 2013Publication date: March 20, 2014Applicant: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Xuan Gao, Gengfeng Zheng
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Patent number: 8575663Abstract: The present invention generally relates, in some aspects, to nanoscale wire devices and methods for use in determining analytes suspected to be present in a sample. Certain embodiments of the invention provide a nanoscale wire that has improved sensitivity, as the carrier concentration in the wire is controlled by an external gate voltage, such that the nanoscale wire has a Debye screening length that is greater than the average cross-sectional dimension of the nanoscale wire when the nanoscale wire is exposed to a solution suspected of containing an analyte. This Debye screening length (lambda) associated with the carrier concentration (p) inside nanoscale wire is adjusted, in some cases, by adjusting the gate voltage applied to an FET structure, such that the carriers in the nanoscale wire are depleted.Type: GrantFiled: November 19, 2007Date of Patent: November 5, 2013Assignee: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Xuan Gao, Gengfeng Zheng
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Patent number: 8232584Abstract: Various aspects of the invention relate to nanoscale wire devices and methods of use for detecting analytes. In one aspect, the invention relates to a nanoscale electrical sensor array device, comprising at least one n-doped semiconductor nanoscale wire and at least one p-doped semiconductor nanoscale wire, each having a reaction entity immobilized thereon. Binding of an analyte to the immobilized reaction entity causes a detectable change in the electrical property of the nanoscale wire. In some embodiments, the reaction entity can be a nucleic acid that may interact with other nucleic acids, proteins, etc. In a specific embodiment, the nucleic acid may interact with an enzyme such as telomerase, which can extend the nucleic acid. In other embodiments, the analyte to be detected can be a toxin, virus or small molecule. Systems and methods of using such nanoscale devices are also disclosed, for example, within a microarray.Type: GrantFiled: August 5, 2009Date of Patent: July 31, 2012Assignee: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Fernando Patolsky, Gengfeng Zheng
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Publication number: 20120167262Abstract: Disclosed are methods of lithography using a tip array having a plurality of pens attached to a backing layer, where the tips can comprise a metal, metalloid, and/or semi-conducting material, and the backing layer can comprise an elastomeric polymer. The tip array can be used to perform a lithography process in which the tips are coated with an ink (e.g., a patterning composition) that is deposited onto a substrate upon contact of the tip with the substrate surface. The tips can be easily leveled onto a substrate and the leveling can be monitored optically by a change in light reflection of the backing layer and/or near the vicinity of the tips upon contact of the tip to the substrate surface.Type: ApplicationFiled: June 4, 2010Publication date: June 28, 2012Applicant: Northwestern UniversityInventors: Chad A. Mirkin, Wooyoung Shim, Adam B. Braunschweig, Xing Liao, Jinan Chai, Jong Kuk Lim, Gengfeng Zheng, Zijian Zheng
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Publication number: 20110305996Abstract: The disclosure relates to methods of beam pen lithography using a tip array having a plurality of transparent, elastomeric, reversibly-deformable tips coated with a blocking layer and apertures defined in the blocking layer to expose tip ends of the tips in the array. The tip array can be used to perform a photolithography process in which the tips are illuminated with a radiation that is channeled through the tips and out the apertures to expose a photosensitive substrate. Also disclosed are tip arrays formed of polymers and gels, apparatus including the tip arrays and radiation sources, and related apparatus for selectively masking tips in the tip array from radiation emitted from the radiation source.Type: ApplicationFiled: February 18, 2010Publication date: December 15, 2011Applicant: NORTHWESTERN UNIVERSITYInventors: Chad A. Mirkin, Gengfeng Zheng, Fengwei Huo
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Publication number: 20110132220Abstract: The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible polymers. The tip array can be prepared using conventional photolithographic methods and can be tailored to have any desired number and/or arrangement of tips. Numerous copies (e.g., greater than 15,000, or greater than 11 million) of a pattern can be made in a parallel fashion in as little as 40 minutes.Type: ApplicationFiled: April 25, 2009Publication date: June 9, 2011Applicant: Northwestern UniversityInventors: Chad A. Mirkin, Fengwei Huo, Zijian Zheng, Gengfeng Zheng
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Publication number: 20100227382Abstract: Various aspects of the present invention generally relate to nanoscale wire devices and methods for use in determining analytes suspected to be present in a sample, and systems and methods of immobilizing entities such as reaction entities relative to nanoscale wires. In one aspect, a nucleic acid, such as DNA, may be immobilized relative to a nanoscale wire, and in some cases, grown from the nanoscale wire. In certain embodiments, the nucleic acid may interact with entities such as other nucleic acids, proteins, etc., and in some cases, such interactions may be reversible. As an example, an enzyme such as telomerase may be allowed to bind to DNA immobilized relative to a nanoscale wire. The telomerase may extend the length of the DNA, for instance, by reaction with free deoxynucleotide triphosphates in solution; additionally, various properties of the nucleic acid may be determined, for example, using electric field interactions between the nucleic acid and the nanoscale wire.Type: ApplicationFiled: August 9, 2006Publication date: September 9, 2010Applicant: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Fernando Patolsky, Gengfeng Zheng
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Publication number: 20100152057Abstract: The present invention generally relates to nanoscale wire devices and methods for use in determining analytes suspected to be present in a sample. The invention provides a nanoscale wire that has improved sensitivity, as the carrier concentration in the wire is controlled by an external gate voltage, such that the nanoscale wire has a Debye screening length that is greater than the average cross-sectional dimension of the nanoscale wire when the nanoscale wire is exposed to a solution suspected of containing an analyte. This Debye screening length (lambda) associated with the carrier concentration (p) inside nanoscale wire is adjusted by adjusting the gate voltage applied to an FET structure, such that the carriers in the nanoscale wire are depleted.Type: ApplicationFiled: November 19, 2007Publication date: June 17, 2010Applicant: President and Fellows of Havard CollegeInventors: Charles M. Lieber, Xuan Gao, Gengfeng Zheng
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Publication number: 20100112546Abstract: Various aspects of the present invention generally relate to nanoscale wire devices and methods for use in determining analytes suspected to be present in a sample, and systems and methods of immobilizing entities such as reaction entities relative to nanoscale wires. In one aspect, a nucleic acid, such as DNA, may be immobilized relative to a nanoscale wire, and in some cases, grown from the nanoscale wire. In certain embodiments, the nucleic acid may interact with entities such as other nucleic acids, proteins, etc., and in some cases, such interactions may be reversible. As an example, an enzyme such as telomerase may be allowed to bind to DNA immobilized relative to a nanoscale wire. The telomerase may extend the length of the DNA, for instance, by reaction with free deoxynucleotide triphosphates in solution; additionally, various properties of the nucleic acid may be determined, for example, using electric field interactions between the nucleic acid and the nanoscale wire.Type: ApplicationFiled: August 5, 2009Publication date: May 6, 2010Applicant: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Fernando Patolsky, Gengfeng Zheng
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Publication number: 20090166222Abstract: A method that combines on-wire-lithography (OWL) nanogaps, an electric field concentrating technique, and surface enhanced Raman spectroscopy (SERS) is disclosed for sensitive detection of analytes with small sample sizes in a chip format.Type: ApplicationFiled: September 8, 2008Publication date: July 2, 2009Applicant: NORTHWESTERN UNIVERSITYInventors: Chad A. Mirkin, Gengfeng Zheng, Lidong Qin
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Publication number: 20060269927Abstract: Various aspects of the present invention generally relate to nanoscale wire devices and methods for use in determining analytes suspected to be present in a sample, and systems and methods of immobilizing entities such as reaction entities relative to nanoscale wires. In one aspect, a nucleic acid, such as DNA, may be immobilized relative to a nanoscale wire, and in some cases, grown from the nanoscale wire. In certain embodiments, the nucleic acid may interact with entities such as other nucleic acids, proteins, etc., and in some cases, such interactions may be reversible. As an example, an enzyme such as telomerase may be allowed to bind to DNA immobilized relative to a nanoscale wire. The telomerase may extend the length of the DNA, for instance, by reaction with free deoxynucleotide triphosphates in solution; additionally, various properties of the nucleic acid may be determined, for example, using electric field interactions between the nucleic acid and the nanoscale wire.Type: ApplicationFiled: May 25, 2005Publication date: November 30, 2006Inventors: Charles Lieber, Fernando Patolsky, Gengfeng Zheng