Patents by Inventor Genhai Zhu

Genhai Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160186204
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: August 14, 2014
    Publication date: June 30, 2016
    Inventors: LU LIU, JESSICA O'REAR, YOUNG JUN PARK, BARBARA ROSEN, UTE SCHELLENBERGER, ERIC SCHEPERS, ZUN-ZHI WEI, WEIPING XIE, NASSER YALPANI, XIAOHONG ZHONG, GENHAI ZHU
  • Publication number: 20160031949
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 4, 2016
    Inventors: Andre R. ABAD, Zhenglin HOU, Lu LIU, Brad POLAND, Ute SCHELLENBERGER, Ingrid UDRANSZKY, Jimei WANG, Jun-Zhi WEI, Thomas C. WOLFE, Weiping XIE, Lan ZHOU, Genhai ZHU
  • Patent number: 9139843
    Abstract: The invention provides novel ?-endotoxin polypeptides, and variants and fragments thereof, obtained from Bacillus thuringiensis having pesticidal activity against nematodes. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, biopesticide compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant parasitic nematodes.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: September 22, 2015
    Assignee: PIONEER HI BRED INTERNATIONAL INC
    Inventors: Ute Schellenberger, Jun-Zhi Wei, Genhai Zhu
  • Publication number: 20140298544
    Abstract: Variant phosphoenolpyruvate carboxylase (PEPC) genes are described. The encoded PEPC variants contain amino acid substitutions and have altered kinetic and/or regulatory properties with respect to wild-type PEPC. A variant PEPC gene may be expressed in a plant to improve one or more traits such as CO2 assimilation rate, water use efficiency, and yield.
    Type: Application
    Filed: October 26, 2012
    Publication date: October 2, 2014
    Inventors: Guofu Li, Lu Liu, Keith Roesler, Daniel L Siehl, Genhai Zhu
  • Publication number: 20140033361
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: March 13, 2013
    Publication date: January 30, 2014
    Applicants: E.I Du PONT de NEMOURS and COMPANY, PIONEER HI BRED INTERNATIONAL INC
    Inventors: Daniel J. Altier, Jennifer K. Barry, Carol A. Hendrick, Lu Liu, Phillip A. Patten, Claudia D. Perez-Ortega, Eric J. Schepers, Weiping Xie, Nasser Yalpani, Jianzhou Zhao, Xiaohong Zhong, Genhai Zhu
  • Patent number: 8637739
    Abstract: The invention provides novel polypeptides, and variants and fragments thereof, having pesticidal activity against nematodes. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, biopesticide compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant parasitic nematodes.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: January 28, 2014
    Assignee: Pioneer Hi Bred International Inc
    Inventors: Steven D. Gruver, Lu Liu, Ute Schellenberger, Jun-Zhi Wei, Wieping Xie, Genhai Zhu
  • Publication number: 20140007292
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: March 11, 2013
    Publication date: January 2, 2014
    Applicant: Pioneer Hi Bred International Inc
    Inventors: David C. Cerf, James J. English, Carol A. Hendrick, Lu Liu, Jarred K. Oral, Phillip A. Patten, Barbara A. Rosen, Ute Schellenberger, Ingrid A. Udranszky, Jun-Zhi Wei, Genhai Zhu
  • Patent number: 8546648
    Abstract: The present invention provides thermostable polypeptides related to Arabidopsis Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: October 1, 2013
    Assignee: Pioneer Hi Bred International Inc
    Inventors: Itzhak Kurek, Lu Liu, Genhai Zhu
  • Publication number: 20130031667
    Abstract: The invention provides novel polypeptides, and variants and fragments thereof, having pesticidal activity against nematodes. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, biopesticide compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant parasitic nematodes.
    Type: Application
    Filed: July 3, 2012
    Publication date: January 31, 2013
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC
    Inventors: Steven D. Gruver, Lu Liu, Ute Schellenberger, Jun-Zhi Wei, Wieping Xie, Genhai Zhu
  • Publication number: 20120304337
    Abstract: The invention provides novel ?-endotoxin polypeptides, and variants and fragments thereof, obtained from Bacillus thuringiensis having pesticidal activity against nematodes. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, biopesticide compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant parasitic nematodes.
    Type: Application
    Filed: May 23, 2012
    Publication date: November 29, 2012
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Ute Schellenberger, Jun-Zhi Wei, Genhai Zhu
  • Patent number: 8129512
    Abstract: Methods for identifying one or more amino acid substitutions in a Rubisco large subunit polypeptide (variant) that confer increased Rubisco activity in a unicellular photosynthetic organism and transferring those substitutions to a Rubisco large subunit polypeptide of a higher plant cell are described herein. Methods and compositions for modulating plant productivity using the modified Rubisco large subunit polypeptide variants are provided. The Rubisco large subunit sequences are used in a variety of methods including increasing plant productivity in a plant. Transformed plants, plant cell, tissues, seed, and expression vectors are also provided.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: March 6, 2012
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Genhai Zhu, Itzhak Kurek, Lu Liu
  • Patent number: 8110113
    Abstract: The present invention provides a method for determining a level of a RuBP, PGA, 2-PA in a photosynthetic cellular extract by resolving at least one RuBP, PGA, or 2-PA or combinations thereof in a photosynthetic cellular extract obtained from a plant. In another aspect, it provides for detecting at least one resolved RuBP, PGA, or 2-PA or combinations, thereby determining a level of the resolved RuBP, PGA, or 2-PA or combinations. In one aspect the photosynthetic cellular extract is obtained from a plant subjected to an abiotic stress. A method of the invention can be useful, for example, for identifying plants with increased photosynthetic performance. Also included herein is a high throughput system for identifying a plant with increased photosynthetic performance.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: February 7, 2012
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Itzhak Kurek, Xuehua Hu, Genhai Zhu, Lu Liu
  • Publication number: 20100175151
    Abstract: The present invention provides thermostable polypeptides related to Arabidopsis Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 8, 2010
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Itzhak Kurek, Lu Liu, Genhai Zhu
  • Patent number: 7723573
    Abstract: The present invention provides thermostable polypeptides related to Arabidopsis Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: May 25, 2010
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Itzhak Kurek, Lu Liu, Genhai Zhu
  • Publication number: 20090241224
    Abstract: The present invention provides thermostable polypeptides related to Arabidopsis Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.
    Type: Application
    Filed: May 29, 2009
    Publication date: September 24, 2009
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Itzhak Kurek, Lu Liu, Genhai Zhu
  • Patent number: 7557267
    Abstract: The present invention provides thermostable polypeptides related to Arabidopsis Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: July 7, 2009
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Itzhak Kurek, Lu Liu, Genhai Zhu
  • Publication number: 20080271209
    Abstract: The present invention provides a method for determining a level of a RuBP, PGA, 2-PA in a photosynthetic cellular extract by resolving at least one RuBP, PGA, or 2-PA or combinations thereof in a photosynthetic cellular extract obtained from a plant. In another aspect, it provides for detecting at least one resolved RuBP, PGA, or 2-PA or combinations, thereby determining a level of the resolved RuBP, PGA, or 2-PA or combinations. In one aspect the photosynthetic cellular extract is obtained from a plant subjected to an abiotic stress. A method of the invention can be useful, for example, for identifying plants with increased photosynthetic performance. Also included herein is a high throughput system for identifying a plant with increased photosynthetic performance.
    Type: Application
    Filed: April 28, 2008
    Publication date: October 30, 2008
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: ITZHAK KUREK, XUEHUA HU, GENHAI ZHU, LU LIU
  • Publication number: 20080256666
    Abstract: Methods for identifying one or more amino acid substitutions in a Rubisco large subunit polypeptide (variant) that confer increased Rubisco activity in a unicellular photosynthetic organism and transferring those substitutions to a Rubisco large subunit polypeptide of a higher plant cell are described herein. Methods and compositions for modulating plant productivity using the modified Rubisco large subunit polypeptide variants are provided. The Rubisco large subunit sequences are used in a variety of methods including increasing plant productivity in a plant. Transformed plants, plant cell, tissues, seed, and expression vectors are also provided.
    Type: Application
    Filed: April 14, 2008
    Publication date: October 16, 2008
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: GENHAI ZHU, ITZHAK KUREK, LU LIU
  • Publication number: 20080072349
    Abstract: The present invention provides thermostable polypeptides related to Arabidopsis Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.
    Type: Application
    Filed: October 5, 2007
    Publication date: March 20, 2008
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Itzhak Kurek, Lu Liu, Genhai Zhu
  • Patent number: 7314975
    Abstract: The present invention provides thermostable polypeptides related to Arabidopsis Rubisco Activase polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nuclei acids of the invention to enhance resistance of plants to heat stress are encompassed.
    Type: Grant
    Filed: August 22, 2006
    Date of Patent: January 1, 2008
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Itzhak Kurek, Lu Liu, Genhai Zhu