Patents by Inventor Genhua ZHENG

Genhua ZHENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRANSPOSOME ENABLED DNA/RNA-SEQUENCING (TED RNA-SEQ)
    Publication number: 20240401033
    Abstract: Provided herein are methods, compositions, and kits for generating a nucleic acid library. In various embodiments provided herein, transposomes comprising transposases are used in forming dual-end tagged nucleic acid molecules for downstream amplification and nucleic acid molecule processing steps.
    Type: Application
    Filed: August 21, 2024
    Publication date: December 5, 2024
    Inventors: Yalei WU, Wai Ho LEE, Genhua ZHENG, Kai Qin LAO
  • Methods and compositions for preparing polynucleotides
    Patent number: 12152271
    Abstract: Provided herein are methods, compositions, and kits for forming amplification products. In various embodiments provided herein, transposomes comprising transposases are used in forming tagged polynucleotides for downstream amplification and polynucleotide processing steps.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: November 26, 2024
    Assignee: CYGNUS BIOSCIENCES (BEIJING) CO., LTD
    Inventors: Yalei Wu, Wai Ho Lee, Genhua Zheng, Kai Qin Lao
  • CYANINE DERIVATIVES AND RELATED USES
    Publication number: 20240240249
    Abstract: The present disclosure provides a compound of Formula (I), (II), or (III): an ionic derivative thereof, an isomer thereof, or a salt thereof. The present disclosure also provides conjugates of the compounds, and methods of using the compounds and the conjugates. The disclosure also provides the use of the compounds and conjugates in methods of sequencing nucleic acids.
    Type: Application
    Filed: January 26, 2024
    Publication date: July 18, 2024
    Inventors: Genhua ZHENG, Njoo Audrey WIBAWA, Xi ZHANG, Zhimin YANG, Marcus James JELLEN, Gene SHEN
  • METHODS AND COMPOSITIONS FOR PREPARING POLYNUCLEOTIDES
    Publication number: 20210230666
    Abstract: Provided herein are methods, compositions, and kits for forming amplification products. In various embodiments provided herein, transposomes comprising transposases are used in forming tagged polynucleotides for downstream amplification and polynucleotide processing steps.
    Type: Application
    Filed: April 25, 2019
    Publication date: July 29, 2021
    Inventors: Yalei WU, Wai Ho LEE, Genhua ZHENG, Kai Qin LAO
  • TRANSPOSOME ENABLED DNA/RNA-SEQUENCING (TED RNA-SEQ)
    Publication number: 20210222163
    Abstract: Provided herein are methods, compositions, and kits for generating a nucleic acid library. In various embodiments provided herein, transposomes comprising transposases are used in forming dual-end tagged nucleic acid molecules for downstream amplification and nucleic acid molecule processing steps.
    Type: Application
    Filed: July 10, 2019
    Publication date: July 22, 2021
    Inventors: Yalei WU, Wai Ho LEE, Genhua ZHENG, Kai Qin LAO