Patents by Inventor Gennadiy Moiseyevich Yershov

Gennadiy Moiseyevich Yershov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid method to detect duplex formation in sequencing by hybridization methods, a method for constructing containment structures for reagent interaction
    Patent number: 6465174
    Abstract: A method for determining the existence of duplexes of oligonucleotide complementary molecules is provided whereby a plurality of immobilized oligonucleotide molecules, each of a specific length and each having a specific base sequence, is contacted with complementary, single stranded oligonucleotide molecules to form a duplex so as to facilitate intercalation of a fluorescent dye between the base planes of the duplex. The invention also provides for a method for constructing oligonucleotide matrices comprising confining light sensitive fluid to a surface, exposing said light-sensitive fluid to a light pattern so as to cause the fluid exposed to the light to polymerize into discrete units and adhere to the surface; and contacting each of the units with a set of different oligonucleotide molecules so as to allow the molecules to disperse into the units.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: October 15, 2002
    Assignee: University of Chicago
    Inventors: Andrei Darievich Mirzabekov, Gennadiy Moiseyevich Yershov, Dmitry Yuryevich Guschin, Margaret Anne Gemmell, Valentine V. Shick, Dmitri Y. Proudnikov, Edward N. Timofeev