Patents by Inventor Gennadiy Nisnevich

Gennadiy Nisnevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6927300
    Abstract: Disclosed is a process for the preparation of the anti-glaucoma drug Latanoprost, in good yield, in large amounts and with desired purity. Also disclosed are novel intermediates for the above process.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: August 9, 2005
    Assignee: FineTech Laboratories LTD
    Inventors: Arie Gutman, Gennadiy Nisnevich, Marina Etinger, Igor Zaltzman, Lev Judovich, Boris Pertsikov
  • Patent number: 6720438
    Abstract: Disclosed is a process for the preparation of the anti-glaucoma drug Latanoprost, in good yield, in large amounts and with desired purity. Also disclosed are novel intermediates for the above process.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: April 13, 2004
    Assignee: FineTech Laboratories Ltd.
    Inventors: Arie Gutman, Gennadiy Nisnevich, Marina Etinger, Igor Zaltzman, Lev Judovich, Boris Pertsikov
  • Patent number: 6696568
    Abstract: A process for preparation of N-(ergoline-8&bgr;-carbonyl)ureas of the formula [I] their stereoisomers as well as acid addition salts thereof which process comprises silylating an ergoline-8&bgr;-carboxamide of the formula [2], their stereoisomers as well as metal or ammonium salts or acid addition salts thereof and reacting the resultant product with an isocyanates R1N═C═O [5] wherein R1 is selected from alkyl having from 1 to 4 carbon atoms, cyclohexyl, phenyl, and dimethylamino alkyl group —(CH2)nNMe2 in which n is an integer, R2 is selected from hydrogen, alkyl having from 1 to 4 carbon atoms, cyclohexyl, phenyl, dimethylamino alkyl group —(CH2)nNMe2 in which n is an integer, pyridyl, pyrimidyl, pyrazinyl, pyridazinyl, thiazolyl or thiadiazolyl, R3 represent a hydrocarbon group having from 1 to 4 carbon atoms, and R4 is selected from hydrogen, halogen, methylthio and phenylthio group;; followed by desilylation.
    Type: Grant
    Filed: April 16, 2001
    Date of Patent: February 24, 2004
    Assignee: Finetech Ltd.
    Inventors: Arie L. Gutman, Gennadiy Nisnevich, Igor Ruchman, Boris Tishin, Alex Vilensky, Boris Pertsikov
  • Publication number: 20030149294
    Abstract: Disclosed is a novel process for the preparation of the anti-glaucoma drug Latanoprost, in good yield, in large amounts and with desired purity. Also disclosed are novel intermediates for the above process.
    Type: Application
    Filed: October 25, 2002
    Publication date: August 7, 2003
    Inventors: Arie Gutman, Gennadiy Nisnevich, Marina Etinger, Igor Zaltzman, Lev Judovich, Boris Pertsikov
  • Publication number: 20020177709
    Abstract: A process for preparation of N-(ergoline-8&bgr;-carbonyl)ureas of the formula [I] their stereoisomers as well as acid addition salts thereof which process comprises silylating an ergoline-8&bgr;-carboxamide of the formula [2], 1
    Type: Application
    Filed: April 16, 2001
    Publication date: November 28, 2002
    Inventors: Arie L. Gutman, Gennadiy Nisnevich, Igor Rukhman, Boris Tishin, Alex Vilensky, Boris Pertsikov