Abstract: A method performed by a computer system including one or more electronic processors and memory includes receiving genomic data, ocular phenotypic data, and receiving ocular clinical diagnosis data for a plurality of subjects. The method also includes identifying a mapping function that maps the genomic data for the plurality of subjects to the ocular clinical diagnosis data for the plurality of subjects and a mapping function that maps the ocular phenotypic data for the plurality of subjects to the ocular clinical diagnosis data for the plurality of subjects. The method may also include obtaining one or more scores indicative of clinical states of an ocular disease for a respective subject of the plurality of subjects. The method may further include treating the plurality of subjects based on the one or more scores.