Abstract: An exemplary method and system for a local cloud infrastructure are disclosed for a pressure elastography-based measurement system, e.g., to provide pre-screening/early screening for breast cancer detection and/or mass detection. The exemplary system comprises a local appliance and gateway that provides cloud infrastructure capabilities in a portable manner to be deployable in a doctor's office or clinic. The exemplary system can operate independently, as well as in conjunction with a regional or global cloud infrastructure, to provide electronic medical record capabilities, appointment management capabilities, as well as teleradiology interface capabilities, e.g., to improve examination workflow and reduce overall operation cost.