Abstract: A wheeled assembly configured to support a trailer. The wheeled assembly includes a frame, a pair of wheels coupled to the frame, a tongue hingedly coupled to a front end portion of the frame that is configured to rotate between a deployed configuration and a stowed configuration, a hitch coupler coupled to the tongue that is configured to connect to a tow vehicle, and a pair of stabilizing jacks coupled to opposite sides of the frame.

Abstract: A platform assembly configured to be coupled to a tower of a sea vessel. The platform assembly includes a platform, a series of brackets configured to be coupled to the platform, and a series of clamps configured to be coupled to the series of brackets. The series of clamps are configured to detachably couple the platform assembly to the tower of the sea vessel.

Abstract: A lifting device includes a base assembly, a hitch assembly coupled to the base assembly, a lift assembly movably coupled to the base assembly, and a trailer attachment assembly coupled to the lift assembly. The hitch attachment assembly is configured to connect to a hitch of a vehicle, and the trailer attachment assembly is configured to connect to a trailer. The base assembly includes a base frame and at least one guide extending upward from the base frame. The lift assembly includes a jack and at least one sleeve coupled to the jack. The sleeve of the lift assembly is in slidable engagement with the guide of the base assembly. Actuation of the jack is configured to raise or lower the lift assembly and the trailer attachment assembly relative to the base assembly and the hitch attachment assembly.

Abstract: An extendable trailer assembly configured to be towed by a vehicle. The extendable trailer assembly includes a first compartment including a floor, a pair of opposing sidewalls, and a ceiling. The first compartment is configured to be coupled to a trailer hitch of the vehicle. The extendable trailer assembly also includes a second compartment including a floor, a pair of opposing sidewalls, and a ceiling. The extendable trailer assembly also includes a slide assembly slidably coupling the second compartment to the first compartment such that the second compartment is slidable relative to the first compartment between a fully extended position and a fully retracted position in which the first compartment is at least partially housed inside of the first compartment. The extendable trailer assembly is free of road-capable wheels for transport by the vehicle.

Abstract: A method is presented for reprogramming cells of a subject. As a starting point, a biological sample of a sample cell is received from the subject, where the sample cell has a given cell type. The method includes: determining gene expression data for the sample cell from the biological sample; receiving gene expression data for a target cell having a target cell type, where the target cell type differs from the given cell type; deriving a state transition matrix which models cell dynamics; computing a regulatory set for a given transcription factor, where the regulatory set quantifies influence of the given transcription factor on a genome; expressing reprogramming of the sample cell to the target cell with a state-space representation of a linear system; and solving for the input vector in the state-space representation.

Abstract: An extendable compartment assembly having a first compartment and a second compartment each having opposing sidewalls and a ceiling, a first frame coupled to the first compartment, a second frame coupled to the second compartment, and a slide assembly coupling the first frame to the second frame such that the second compartment is slideable relative to the first compartment between a first position and a second position. In the first position, the second compartment is at least partially disposed within the first compartment and in the second position the second compartment is at least partially disposed outside the first compartment. A hitch assembly comprising a base arm having first and second ends, a first mating arm coupled with the first end, a second mating arm coupled with the second end, and a bias member coupling the first mating arm to the second mating arm.

Abstract: An extendable trailer assembly configured to be towed by a vehicle. The extendable trailer assembly includes a first compartment including a floor, a pair of opposing sidewalls, and a ceiling. The first compartment is configured to be coupled to a trailer hitch of the vehicle. The extendable trailer assembly also includes a second compartment including a floor, a pair of opposing sidewalls, and a ceiling. The extendable trailer assembly also includes a slide assembly slidably coupling the second compartment to the first compartment such that the second compartment is slidable relative to the first compartment between a fully extended position and a fully retracted position in which the first compartment is at least partially housed inside of the first compartment. The extendable trailer assembly is free of road-capable wheels for transport by the vehicle.

Abstract: An extendable compartment assembly having a first compartment and a second compartment each having opposing sidewalls and a ceiling, a first frame coupled to the first compartment, a second frame coupled to the second compartment, and a slide assembly coupling the first frame to the second frame such that the second compartment is slideable relative to the first compartment between a first position and a second position. In the first position, the second compartment is at least partially disposed within the first compartment and in the second position the second compartment is at least partially disposed outside the first compartment. A hitch assembly comprising a base arm having first and second ends, a first mating arm coupled with the first end, a second mating arm coupled with the second end, and a bias member coupling the first mating arm to the second mating arm.

Abstract: An extendable compartment assembly having a first compartment and a second compartment each having opposing sidewalls and a ceiling, a first frame coupled to the first compartment, a second frame coupled to the second compartment, and a slide assembly coupling the first frame to the second frame such that the second compartment is slideable relative to the first compartment between a first position and a second position. In the first position, the second compartment is at least partially disposed within the first compartment and in the second position the second compartment is at least partially disposed outside the first compartment. A hitch assembly comprising a base arm having first and second ends, a first mating arm coupled with the first end, a second mating arm coupled with the second end, and a bias member coupling the first mating arm to the second mating arm.

Abstract: An extendable compartment assembly having a first compartment and a second compartment each having opposing sidewalls and a ceiling, a first frame coupled to the first compartment, a second frame coupled to the second compartment, and a slide assembly coupling the first frame to the second frame such that the second compartment is slideable relative to the first compartment between a first position and a second position. In the first position, the second compartment is at least partially disposed within the first compartment and in the second position the second compartment is at least partially disposed outside the first compartment. A hitch assembly comprising a base arm having first and second ends, a first mating arm coupled with the first end, a second mating arm coupled with the second end, and a bias member coupling the first mating arm to the second mating arm.

Abstract: An exercise hoop is assembled from arcuate segments attached end to end. Each segment has a base with male and female fittings at opposite ends and a sidewall extending between the ends. The sidewall defines a central space and a centerline. A cover attaches to the base. The base and the cover have reinforcing bulkheads to prevent kinking and use stirrups to engage legs having feet deflected by a deflector body to provide positive mechanical engagement between the base and the cover to secure each to the other. End to end attachment of the segments is secured using a spring biased button detent in the male fitting that engages an opening in the female fitting.