Abstract: The claimed invention relates to treating cancer by targeting CD36, a fatty acid receptor. The claimed invention also relates to treating cancer metastases by targeting CD36. The invention involves using anti-CD36 antibodies as blockers or inhibitors of CD36 activity.

Abstract: Provided are proteins comprising a variant IgG Fc region, wherein the proteins exhibit significantly reduced binding to human Fc?RI when compared with a reference protein comprising the amino acid substitutions L234A/L235A/P329G. Also provided are compositions, methods of treatment and methods to reduce Fc-induced effector functions in a parent protein.

Abstract: A suspension clamp is disclosed for clamping a disk drive suspension to an actuator arm. The suspension clamp comprises a housing including a spring operable to bias a latching member, wherein the latching member is rotatable about a pivot. After compressing the spring and rotating the latching member in a first direction, the latching member is operable to clamp the suspension to the actuator arm by decompressing the spring.

Abstract: A suspension clamp is disclosed for clamping a disk drive suspension to an actuator arm. The suspension clamp comprises a housing including a spring operable to bias a latching member, wherein the latching member is rotatable about a pivot. After compressing the spring and rotating the latching member in a first direction, the latching member is operable to clamp the suspension to the actuator arm by decompressing the spring.

Abstract: A transfer tool is disclosed for clamping a disk drive suspension to an actuator arm. The transfer tool comprises a first actuator operable to actuate at least one push pin to compress a spring of a suspension clamp, and a second actuator operable to actuate a driving pin, wherein the driving pin for rotating a latching member of the suspension clamp about a pivot.

Abstract: A suspension clamp is disclosed for clamping a disk drive suspension to an actuator arm. The suspension clamp comprises a housing including a spring operable to bias a latching member, wherein the latching member is rotatable about a pivot. After compressing the spring and rotating the latching member in a first direction, the latching member is operable to clamp the suspension to the actuator arm by decompressing the spring.

Abstract: Removable actuator assemblies for testing head gimbal assemblies of a storage device are provided. One such removable test assembly for a head gimbal assembly (HGA) includes an actuator base including at least one guide pin, a shoe assembly including a body including a first end portion opposite to a second end portion, a first attachment means for releaseably coupling the shoe assembly with the actuator base, the first attachment means positioned along the first end portion and including at least one hole in the body configured to receive the at least one guide pin, and a locking cam configured to rotate such that a portion of the cam is positioned over a portion of the at least one hole, and a second attachment means for releaseably coupling the shoe assembly with the HGA, the second attachment means positioned along the second end portion.

Abstract: The present invention is a method of doing business over a network that: receives a request for transmitting digital information after a start time and before an end time, determines the time required to transmit the digital information based on the number of packets in the information and the network speed, schedules a transmit time for the digital information, and accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time. Pricing of the transmission can be determined by the priority of transmission, whether the information is transmitted the first time or rescheduled, and whether the user receives an acknowledgment.

Abstract: The present invention is a computer system for delivering digital information over a network. A request receiving process receives a request for transmitting digital information after a start time and before an end time. The digital information has a number of packets. A transmit time process determines the time required to transmit the digital information based on the number of packets and a network speed. A scheduler schedules a transmit time for the digital information and an acceptance process accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time.

Abstract: The present invention is a method of doing business over a network that: receives a request for transmitting digital information after a start time and before an end time, determines the time required to transmit the digital information based on the number of packets in the information and the network speed, schedules a transmit time for the digital information, and accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time. Pricing of the transmission can be determined by the priority of transmission, whether the information is transmitted the first time or rescheduled, and whether the user receives an acknowledgment.

Abstract: The present invention is a method of doing business over a network that: receives a request for transmitting digital information after a start time and before an end time, determines the time required to transmit the digital information based on the number of packets in the information and the network speed, schedules a transmit time for the digital information, and accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time. Pricing of the transmission can be determined by the priority of transmission, whether the information is transmitted the first time or rescheduled, and whether the user receives an acknowledgment.

Abstract: The present invention is a computer system for delivering digital information over a network. A request receiving process receives a request for transmitting digital information after a start time and before an end time. The digital information has a number of packets. A transmit time process determines the time required to transmit the digital information based on the number of packets and a network speed. A scheduler schedules a transmit time for the digital information and an acceptance process accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time.

Abstract: The present invention is a method of doing business over a network that: receives a request for transmitting digital information after a start time and before an end time, determines the time required to transmit the digital information based on the number of packets in the information and the network speed, schedules a transmit time for the digital information, and accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time. Pricing of the transmission can be determined by the priority of transmission, whether the information is transmitted the first time or rescheduled, and whether the user receives an acknowledgment.

Abstract: The present invention is a method of doing business over a network that: receives a request for transmitting digital information after a start time and before an end time, determines the time required to transmit the digital information based on the number of packets in the information and the network speed, schedules a transmit time for the digital information, and accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time. Pricing of the transmission can be determined by the priority of transmission, whether the information is transmitted the first time or rescheduled, and whether the user receives an acknowledgment.

Abstract: The present invention is a method of doing business over a network that: receives a request for transmitting digital information after a start time and before an end time, determines the time required to transmit the digital information based on the number of packets in the information and the network speed, schedules a transmit time for the digital information, and accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time. Pricing of the transmission can be determined by the priority of transmission, whether the information is transmitted the first time or rescheduled, and whether the user receives an acknowledgment.

Abstract: The present invention is a computer system for delivering digital information over a network. A request receiving process receives a request for transmitting digital information after a start time and before an end time. The digital information has a number of packets. A transmit time process determines the time required to transmit the digital information based on the number of packets and a network speed. A scheduler schedules a transmit time for the digital information and an acceptance process accepts the digital information for transmission only if the time required to transmit is less than or equal to the difference between the transmit time and the end time.

Abstract: A computer dispatcher connected to one or more respective network buffers has stored file lists that identify one or more of the files in the database that are to be transmitted over networks connected to the respective network buffer. A scheduler(s) schedule one or more portions of one or more of the files to be written to the respective network buffers by defining transmission criteria about each of the files in the file list. These transmission criteria include a quantity to transmit criteria, defining a quantity of one or more of the portions of the respective file to transmit, and one or more release times. The release times define the time at which the respective portion is to be written to the network buffer. The system includes a dispatching process that determines an available space on one or more of the network buffers and a current system time.

Abstract: The invention relates to the use of an antibody recognising the CDw52 antigen in the treatment of multiple sclerosis. Preferably the antibody is the humanised antibody in the humanised antibody CAMPATH-1H.

Abstract: Use of an aglycosylated antibody having a binding affinity for the CD3 antigen complex is provided for the manufacture of a medicament for treatment of chronic joint inflammation, and more particularly for treating Rheumatoid Arthritis.

Abstract: The invention is a broadband network monitoring system and method. The system has one or more RF carrier generators that generate one or more generator signals, called a reference signal, each of the generator signals having a generator signal frequency. One or more RF transient detectors sense a line signal on one or more broadband lines in the broadband network. Each line signal has one or more test signals applied by a remote RF carrier generator. Each test signal has a frequency equal to one of the reference signals. Each RF transient detector senses and compares the test signal and the reference signal in various ways to produce a transient indicator when the test signal and reference/generator signal are not the same. The transient indicator indicates that there may be a perturbation or some other problem in the respective broadband line. A controller is connected to each of the RF transient detectors and controls an RF switch and an analyzer.