Abstract: An oral care device having a head with cleaning elements and a handle coupled to the head. The handle may include a selectively rotatable ring arranged between the head and a distal end of the handle that is configured to allow a user to select a desired mode of operation of the oral care device. The handle may include a selectively illuminated light that is configured to display at least one color that visually indicates that certain behaviors, patterns, and/or consistent habits have been performed successfully. The handle may include a processor configured to track a duration of a user's brushing session, a light ring on a bottom surface of the handle, and a pressure sensor. Respective portions of the light ring may be selectively illuminated by the processor to visualize progress toward achieving a predetermined brushing routine time and/or to visualize an over-pressure condition sensed by the pressure sensor.

Abstract: An oral care device having a head with cleaning elements and a handle coupled to the head. The handle may include a selectively rotatable ring arranged between the head and a distal end of the handle that is configured to allow a user to select a desired mode of operation of the oral care device. The handle may include a selectively illuminated light that is configured to display at least one color that visually indicates that certain behaviors, patterns, and/or consistent habits have been performed successfully. The handle may include a processor configured to track a duration of a user's brushing session, a light ring on a bottom surface of the handle, and a pressure sensor. Respective portions of the light ring may be selectively illuminated by the processor to visualize progress toward achieving a predetermined brushing routine time and/or to visualize an over-pressure condition sensed by the pressure sensor.

Abstract: An oral care device having a head with cleaning elements and a handle coupled to the head. The handle may include a selectively rotatable ring arranged between the head and a distal end of the handle that is configured to allow a user to select a desired mode of operation of the oral care device. The handle may include a selectively illuminated light that is configured to display at least one color that visually indicates that certain behaviors, patterns, and/or consistent habits have been performed successfully. The handle may include a processor configured to track a duration of a user's brushing session, a light ring on a bottom surface of the handle, and a pressure sensor. Respective portions of the light ring may be selectively illuminated by the processor to visualize progress toward achieving a predetermined brushing routine time and/or to visualize an over-pressure condition sensed by the pressure sensor.

Abstract: An oral care device having a head with cleaning elements and a handle coupled to the head. The handle may include a selectively rotatable ring arranged between the head and a distal end of the handle that is configured to allow a user to select a desired mode of operation of the oral care device. The handle may include a selectively illuminated light that is configured to display at least one color that visually indicates that certain behaviors, patterns, and/or consistent habits have been performed successfully. The handle may include a processor configured to track a duration of a user's brushing session, a light ring on a bottom surface of the handle, and a pressure sensor. Respective portions of the light ring may be selectively illuminated by the processor to visualize progress toward achieving a predetermined brushing routine time and/or to visualize an over-pressure condition sensed by the pressure sensor.

Abstract: The invention provides nanocages, and in particular to protein nanocages, and especially ferritin nanocages. The invention extends to variant ferritin polypeptides and their encoding nucleic acids, mutant ferritin nanocages, and their uses in diagnostics and drug delivery, as well as in phenotypic screens in drug development.

Abstract: A method of continuously transferring a web of material from a large roll to a smaller roll involves the performance of at least one processing step including printing during the continuous transfer of the web of material from the large roll to the smaller roll. A system for performing the method continuously transfers a web of material from a large roll to a smaller roll while performing at least one processing step on the web of material during the continuous transfer thereof.