Patents by Inventor Geoffrey Cole

Geoffrey Cole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYP1B1 NUCLEIC ACIDS AND METHODS OF USE
    Publication number: 20120201843
    Abstract: The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 transcript. The nucleic acids of the invention lack translational repressor elements and thus provide for a system of enhanced translation of the CYP1B1 polypeptide or portions thereof. Also disclosed are methods of administering nucleic acids to a mammal and use in the treatment of proliferative disorders or cancer.
    Type: Application
    Filed: March 19, 2012
    Publication date: August 9, 2012
    Applicant: Eisai, Inc.
    Inventors: Nazneen Aziz, Mary Lynne Hedley, Robert G. Urban, Andrew J. Tomlinson, Geoffrey Cole
  • CYP1B1 nucleic acids and methods of use
    Patent number: 8158594
    Abstract: The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 transcript. The nucleic acids of the invention lack translational repressor elements and thus provide for a system of enhanced translation of the CYP1B1 polypeptide or portions thereof. Also disclosed are methods of administering nucleic acids to a mammal and use in the treatment of proliferative disorders or cancer.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: April 17, 2012
    Assignee: Eisai Inc.
    Inventors: Nazneen Aziz, Mary Lynne Hedley, Robert G. Urban, Andrew J. Tomlinson, Geoffrey Cole
  • CYP1B1 NUCLEIC ACIDS AND METHODS OF USE
    Publication number: 20100233087
    Abstract: The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 transcript. The nucleic acids of the invention lack translational repressor elements and thus provide for a system of enhanced translation of the CYP1B1 polypeptide or portions thereof. Also disclosed are methods of administering nucleic acids to a mammal and use in the treatment of proliferative disorders or cancer.
    Type: Application
    Filed: April 30, 2007
    Publication date: September 16, 2010
    Applicant: MGI PHARMA BIOLOGICS, INC.
    Inventors: Nazneen Aziz, Mary Lynne Hedley, Robert G. Urban, Andrew J. Tomlinson, Geoffrey Cole
  • CYP1B1 nucleic acids and methods of use
    Patent number: 7241742
    Abstract: The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 transcript. The nucleic acids of the invention lack translational repressor elements and thus provide for a system of enhanced translation of the CYP1B1 polypeptide or portions thereof. Also disclosed are methods of administering nucleic acids to a mammal and use in the treatment of proliferative disorders or cancer.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: July 10, 2007
    Assignee: MGI PHARMA Biologics, Inc.
    Inventors: Nazneen Aziz, Mary Lynne Hedley, Robert G. Urban, Andrew J. Tomlinson, Geoffrey Cole
  • CYP1B1 nucleic acids and methods of use
    Publication number: 20030028000
    Abstract: The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 transcript. The nucleic acids of the invention lack translational repressor elements and thus provide for a system of enhanced translation of the CYP1B1 polypeptide or portions thereof. Also disclosed are methods of administering nucleic acids to a mammal and use in the treatment of proliferative disorders or cancer.
    Type: Application
    Filed: October 31, 2001
    Publication date: February 6, 2003
    Inventors: Nazneen Aziz, Mary Lynne Hedley, Robert G. Urban, Andrew J. Tomlinson, Geoffrey Cole
  • Backpack straps
    Patent number: D809799
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: February 13, 2018
    Assignee: Nesel LLC
    Inventors: Martha Pietruszewski, Geoffrey Cole McCloskey