Abstract: The invention relates to a test sensor and a heater and thermocouple device for use in a test sensor and other assays, such as a diagnostic test sensor or strip and to a method of manufacturing a test sensor and a device and a method of conducting an assay using the test sensor or device. The invention relates to a test sensor comprising a heater and thermocouple device (100), the heater and thermocouple device (100) comprising: a substrate (10); on the substrate (10), a first layer (12) of a first conductive material of a first conductivity comprising: a first thermocouple element (14); a first connector track (16) connected to the first thermocouple element (14); a resistive heater element (20); and in which at least part of the first thermocouple element (14) is comprised of a portion of the resistive heater element (20); a second layer (22) of a second conductive material of a second conductivity comprising: a second thermocouple element (24) in contact with the first thermocouple element (14) (e.g.

Abstract: The invention relates to a method of and apparatus for determining concentration of an analyte, such as glucose, in a fluid sample, such as body fluid or control solution, using a mediated redox reaction. In particular, the method relates to mitigation of the effects of haematocrit on the response of sensor device used in such a method or apparatus.

Abstract: The present invention relates to a sensor device for measuring a level of an analyte of interest in a fluid, such as body fluid (for example blood, plasma, urine, interstitial fluid, saliva), a method of manufacturing a sensor device, a reagent film for use in a sensor, a method of manufacturing a reagent film for use in a sensor, a method of conducting an assay using a sensor, a method of calibrating a measurement from a sensor, a method of calibrating a batch of sensors, a meter for use with a sensor and a kit comprising a meter and a sensor according to the invention. A first aspect of the invention provides a sensor device for measuring a level of an analyte of interest In a fluid comprising: a flowpath for the fluid; on the flowpath, a reagent for the analyte of interest adjacent to an internal standard comprising a first predetermined amount of a first calibration analyte; and further wherein the reagent and the predetermined amount of a first calibration analyte are in dry form.

Abstract: The invention relates to a method of and apparatus for determining concentration of an analyte, such as glucose, in a fluid sample, such as body fluid or control solution, using a mediated redox reaction. In particular, the method relates to mitigation of the effects of haematocrit on the response of sensor device used in such a method or apparatus.

Abstract: The present invention relates to a sensor device for measuring a level of an analyte of interest in a fluid, such as body fluid (for example blood, plasma, urine, interstitial fluid, saliva), a method of manufacturing a sensor device, a reagent film for use in a sensor, a method of manufacturing a reagent film for use in a sensor, a method of conducting an assay using a sensor, a method of calibrating a measurement from a sensor, a method of calibrating a batch of sensors, a meter for use with a sensor and a kit comprising a meter and a sensor according to the invention. A first aspect of the invention provides a sensor device for measuring a level of an analyte of interest In a fluid comprising: a flowpath for the fluid; on the flowpath, a reagent for the analyte of interest adjacent to an internal standard comprising a first predetermined amount of a first calibration analyte; and further wherein the reagent and the predetermined amount of a first calibration analyte are in dry form.

Abstract: A disposable electrochemical sensor for the detection of an analyte such as glucose in a liquid sample is provided. The sensor has a working electrode and a reference electrode disposed within a sample-receiving cavity, and a reagent layer disposed within the sample-receiving cavity and over the working electrode. The reagent layer contains at least an enzyme for producing an electrochemical signal in the presence of the analyte. The sample-receiving cavity has a volume of less than 1.5 &mgr;l, and the sensor provides a stable reading of the amount of analyte in a period of 10 seconds or less. Where appropriate for the generation of electrochemical signal, for example in the case of glucose detection, the reagent layer also contains a mediator. The sensor is used in combination with a meter for detection of the analyte in a liquid sample.

Abstract: A disposable electrochemical sensor for the detection of an analyte such as glucose in a liquid sample is provided. The sensor has a working electrode and a reference electrode disposed within a sample-receiving cavity, and a reagent layer disposed within the sample-receiving cavity and over the working electrode. The reagent layer contains at least an enzyme for producing an electrochemical signal in the presence of the analyte. The sample-receiving cavity has a volume of less than 1.5 &mgr;l, and the sensor provides a stable reading of the amount of analyte in a period of 10 seconds or less. Where appropriate for the generation of electrochemical signal, for example in the case of glucose detection, the reagent layer also contains a mediator. The sensor is used in combination with a meter for detection of the analyte in a liquid sample.