Patents by Inventor Geoffrey Gymer

Geoffrey Gymer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6979690
    Abstract: This invention provides compounds of the formula (I) and (II): or the pharmaceutically acceptable esters thereof, and the pharmaceutically acceptable salts thereof: wherein R1 is hydrogen or halo; R2 and R3 are independently hydrogen or C1-6 alkyl; R4 and R5 are independently hydrogen or C1-6 alkyl; R6 is hydrogen, C1-12 alkyl, C1-6 alkoxy (C1-6)alkyl or C1-12 alkyl substituted by up to 3 substituents selected from the groups consisting of C3-8 cycloalkyl, aryl, heteroaryl and heterocyclic; R7 and R8 are hydrogen or taken together may form alkylene chain having one or two carbon atoms; R9 is C1-6 alkyl or C3-8 cycloalkyl; R10 is C1-6 alkyl or NR11R12; L is (CR11R12)n or NR11; M is NR11 or (CR11R12)n; R11 and R12 are independently hydrogen or C1-6 alkyl; n is an integer from 0 to 5; and m is an integer from 0 to 2; said heterocyclic, aryl and heteroaryl are unsubstituted or are substituted by at least one substituent selected from the group consisting of halo and C1-6 alkyl; with the proviso that when R9 i
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: December 27, 2005
    Assignee: Pfizer Inc.
    Inventors: Geoffrey Gymer, Kiyoshi Kawamura, Sachiko Mihara, Mikio Morita, Alan Stobie, Chikara Uchida, Seiji Nukui
  • Publication number: 20040034226
    Abstract: This invention provides a compound of the formula (I): 1
    Type: Application
    Filed: July 10, 2003
    Publication date: February 19, 2004
    Inventors: Chikara Uchida, Hirohide Noguchi, Alan Stobie, Geoffrey Gymer, David Fenwick
  • Publication number: 20030207875
    Abstract: This invention provides compounds of the formula (I) and (II): 1
    Type: Application
    Filed: January 7, 2003
    Publication date: November 6, 2003
    Inventors: Geoffrey Gymer, Kiyoshi Kawamura, Sachiko Mihara, Mikio Morita, Alan Stobie, Chikara Uchida, Seiji Nukui
  • Patent number: 6624162
    Abstract: This invention provides a compound of the formula (I): or the pharmaceutically acceptable salts thereof wherein R1 is hydrogen, halo or alkyl; R2 and R3 are independently hydrogen, alkyl, alkenyl, alkynyl, aminoalkyl or hydroxyalkyl; or R2 and R3 taken together with the nitrogen atom to which they are attached may form hetrocyclic; R4 is hydrogen, halo, acyl, amino, amido, aryl, arylalkyl, or heteroaryl; R5 is hydrogen, halo, alkyl alkenyl, alkynyl, acyl, amino, amido, aryl, arylalkyl, or heteroaryl; R6 is hydrogen, alkyl or alkoxyalkyl; X is NR9 wherein R9 is hydrogen or alkyl; and Y is (CR7R8)n wherein n is an integer from 0 to 5. These compounds have 5-HT4 receptor binding activity, and thus are useful for the treatment of gastroesophageal reflux disease, non-ulcer dyspepsia, Functional dyspepsia, irritable bowel syndrome or the like in mammalian, especially humans. This invention also provides a pharmaceutical composition comprising the above compound.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: September 23, 2003
    Assignee: Pfizer Inc.
    Inventors: Chikara Uchida, Hirohide Noguchi, Alan Stobie, Geoffrey Gymer, David Fenwick
  • Publication number: 20030092699
    Abstract: This invention provides a compound of the formula (I): 1
    Type: Application
    Filed: September 20, 2002
    Publication date: May 15, 2003
    Inventors: Chikara Uchida, Hirohide Noguchi, Alan Stobie, Geoffrey Gymer, David Fenwick
  • Patent number: 4483863
    Abstract: Compounds of the general formula: ##STR1## wherein Ar is dichlorophenyl and Het is 1-methyltetrazol-5-yl, 1,2,4-triazol-3-yl, 1-methyl-1,2,4-triazol-3-yl, 2-methyl-1,2,4-triazol-3-yl, 4-methyl-1,2,4-triazol-3-yl, imidazol-2-yl or 1-methylimidazol-2-yl and their pharmaceutically acceptable acid addition salts are antifungal agents in humans and other animals.
    Type: Grant
    Filed: January 20, 1984
    Date of Patent: November 20, 1984
    Assignee: Pfizer Inc.
    Inventors: Kenneth Richardson, Geoffrey Gymer