Patents by Inventor Geoffrey H. Baker

Geoffrey H. Baker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing parasiticidal milbemycin derivatives by culturing streptomyces
    Patent number: 5620874
    Abstract: Compounds of formula (I): ##STR1## wherein R.sup.1 is hydrogen or methyl, R.sup.2 is hydrogen or (E)-2-methyl 2-butenoyloxy, and R.sup.3 is hydrogen or hydroxy, with the proviso that when R.sup.3 is hydrogen, R.sup.1 and R.sup.2 are both hydrogen, and when R.sup.2 is (E)-2-methyl 2-butenoyloxy, R.sup.1 is methyl; the compound of formula (II): ##STR2## and the compound of formula (III): ##STR3## are obtainable by the fermentation of Streptomyces E225 NCIB 12310 or Streptomyces E225B NCIB 12509. The compounds have antihelminthic utility.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: April 15, 1997
    Assignee: Pfizer Inc.
    Inventors: Rhona M. Banks, Geoffrey H. Baker, Roderick J. Dorgan, Mark E. Poulton
  • Compounds
    Patent number: 5569672
    Abstract: Crystalline calcium pseudomonate or a hydrate thereof, in particular the dihydrate.Processes for the preparation of these salts and their use in human and veterinary medicine and as a growth promoter in animals are described.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: October 29, 1996
    Assignee: Beecham Group p.l.c.
    Inventors: Geoffrey H. Baker, Merle Beal
  • Compounds
    Patent number: 5436266
    Abstract: Crystalline calcium pseudomonate or a hydrate thereof, in particular the dihydrate. Processes for the preparation of these salts and their use in human and veterinary medicine and as a growth promoter in animals are described.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: July 25, 1995
    Assignee: Beecham Group p.l.c.
    Inventors: Geoffrey H. Baker, Merle Beal
  • Process for preparing crystalline calcium pseudomonate
    Patent number: 5191093
    Abstract: Processes for the preparation of these salts and their use in human and veterinary medicine and as a growth promoter in animals are described.
    Type: Grant
    Filed: March 12, 1990
    Date of Patent: March 2, 1993
    Assignee: Beecham Group p.l.c.
    Inventors: Geoffrey H. Baker, Merle Beal
  • Derivatives of avermectin and milbemycin
    Patent number: 5055596
    Abstract: Compounds of formula (I): ##STR1## wherein R.sup.1 is hydrogen or optionally protected hydroxy; R.sup.2 is alkoxy, optionally protected hydroxy, oxo or optionally O-substituted oximino; R.sup.3 is hydrogen, optionally protected hydroxy, or a group 4'-(.alpha.-L-oleandrosyl)-.alpha.-L-oleandrosyloxy or .alpha.-L-oleandrosyloxy wherein the terminal hydroxy group is optionally protected; one or R.sup.4 and R.sup.5 is hydrogen and the other is methyl; and one of R.sup.6 and R.sup.7 is hydrogen and the other is methyl; with the proviso that (a) when R.sup.1 is optionally protected hydroxy, R.sup.3 is hydrogen, and (b) when R.sup.2 is not methoxy or optionally protected hydroxy, R.sup.1 and R.sup.3 are both hydrogen, are new and useful as anthelmintic agents.
    Type: Grant
    Filed: July 30, 1990
    Date of Patent: October 8, 1991
    Assignee: Beecham Group p.l.c.
    Inventors: Geoffrey H. Baker, Roderick J. Dorgan, David O. Morgan, Rhona M. Banks, Simon E. Blanchflower, Mark E. Poulton, Peter R. Shelley
  • Crystalline calcium pseudomonate
    Patent number: 4916155
    Abstract: Crystalline calcium pseudomonate or a hydrate thereof, in particular the dihydrate.Processes for the preparation of these salts and their use in human and veterinary medicine and as a growth promoter in animals are described.
    Type: Grant
    Filed: April 13, 1989
    Date of Patent: April 10, 1990
    Assignee: Beecham Group p.l.c.
    Inventors: Geoffrey H. Baker, Merle Beal
  • Amidines
    Patent number: 4596818
    Abstract: A compound of formula (I): ##STR1## or a salt thereof wherein R.sup.1 is halogen, C.sub.1-4 alkyl or C.sub.1-4 alkoxyR.sup.2 is hydrogen, halogen, C.sub.1-4 alkyl or C.sub.1-4 alkoxyR.sup.3 and R.sup.4 are the same or different and each is hydrogen, C.sub.1-4 alkyl or acyl andR.sup.5 is either (i) ##STR2## wherein R.sup.6, R.sup.7 and R.sup.8 are the same or different and each is selected from hydrogen, halogen, alkyl, alkoxy, hydroxy, hydroxyalkyl, alkoxyalkyl, mercapto, mercaptoalkyl, amino, aminoalkyl, nitro, cyano, carboxy or a salt, ester or amide of carboxy provided that at least one of R.sup.6, R.sup.7 and R.sup.8 is other than hydrogen or (ii) ##STR3## wherein R.sup.9, R.sup.10 and R.sup.11 are the same or different and each is selected from hydrogen, halogen, alkyl, alkoxy, hydroxy, hydroxyalkyl, alkoxyalkyl, mercapto, mercaptoalkyl, amino, aminoalkyl, nitro, cyano, carboxy or a salt, ester or amide of carboxyand X is --CH.sub.2 -- or --CH.dbd.CH-- or (iii) ##STR4## wherein R.sup.12 and R.sup.
    Type: Grant
    Filed: February 16, 1984
    Date of Patent: June 24, 1986
    Assignee: Beecham Group p.l.c.
    Inventors: Peter M. Newsome, Lee J. Beeley, Stephen F. Moss, Geoffrey H. Baker