Patents by Inventor Geoffrey M. Bilcer

Geoffrey M. Bilcer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY
    Publication number: 20170166561
    Abstract: Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating ?7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.
    Type: Application
    Filed: July 8, 2015
    Publication date: June 15, 2017
    Inventors: Geoffrey M. BILCER, Raymond NG
  • Quinuclidines for modulating alpha 7 activity
    Patent number: 9434724
    Abstract: Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating ?7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: September 6, 2016
    Assignee: ALPHARMAGEN, LLC
    Inventors: Geoffrey M. Bilcer, Raymond Ng
  • QUINUCLIDINES FOR MODULATING ALPHA 7 ACTIVITY
    Publication number: 20160009706
    Abstract: Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating ?7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.
    Type: Application
    Filed: July 8, 2015
    Publication date: January 14, 2016
    Inventors: Geoffrey M. BILCER, Raymond NG
  • PYRROLIDINE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
    Publication number: 20130102593
    Abstract: Described herein are novel beta-secretase inhibitors and methods for their use, including methods of treating Alzheimer's disease.
    Type: Application
    Filed: October 9, 2009
    Publication date: April 25, 2013
    Inventors: Geoffrey M. Bilcer, Thippeswamy Devasamudram, Sudha V. Ankala, John C. Lilly, Chunfeng Liu, Hui Lei, Arun K. Ghosh, Makoto Inoue
  • SULFONAMIDO PYRROLIDINE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
    Publication number: 20130059840
    Abstract: Described herein are novel beta-secretase inhibitors and methods for their use, including methods of treating Alzheimer's disease.
    Type: Application
    Filed: October 4, 2010
    Publication date: March 7, 2013
    Applicant: CoMentis, Inc.
    Inventors: Geoffrey M. Bilcer, Sudha V. Ankala
  • PYRROLIDINE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
    Publication number: 20120295894
    Abstract: Described herein are novel beta-secretase inhibitors and methods for their use, including methods of treating Alzheimer's disease.
    Type: Application
    Filed: December 1, 2011
    Publication date: November 22, 2012
    Inventors: Geoffrey M. BILCER, Thippeswamy Devasamudram, Sudha V. Ankala, John C. Lilly, Chunfeng Liu, Hui Lei, Arun K. Ghosh, Makoto Inoue
  • (3-hydroxy-4-amino-butan-2-yl) -3- (2-thiazol-2-yl-pyrrolidine-1-carbonyl) benzamide derivatives and related compounds as beta-secretase inhibitors for treating
    Patent number: 8299267
    Abstract: The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: October 30, 2012
    Assignees: CoMentis, Inc., Purdue Research Foundation
    Inventors: Arun K. Ghosh, Chunfeng Liu, Thippeswamy Devasamudram, Hui Lei, Lisa M. Swanson, Sudha V. Ankala, John C. Lilly, Geoffrey M. Bilcer
  • PYRROLIDINE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
    Publication number: 20120214802
    Abstract: Described herein are novel beta-secretase inhibitors and methods for their use, including methods of treating Alzheimer's disease.
    Type: Application
    Filed: October 9, 2009
    Publication date: August 23, 2012
    Inventors: Geoffrey M. Bilcer, Thippeswamy Devasamudram, Sudha V. Ankala, John C. Lilly, Chunfeng Liu, Hui Lei, Arun K. Ghosh, Makoto Inoue
  • HIV protease inhibitors
    Patent number: 7897635
    Abstract: Compounds useful for inhibiting HIV protease are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating wild-type HIV and of multidrug-resistant strains of HIV, also are disclosed.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: March 1, 2011
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Arun K. Ghosh, Geoffrey M. Bilcer, Thippeswamy Devasamudram
  • (3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING
    Publication number: 20100286170
    Abstract: The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease.
    Type: Application
    Filed: September 24, 2008
    Publication date: November 11, 2010
    Inventors: Arun K. Ghosh, Chunfeng Liu, Thippeswamy Devasamudram, Hui Lei, Lisa M. Swanson, Sudha V. Ankala, John C. Lilly, Geoffrey M. Bilcer
  • ISOPHTHALAMIDE DERIVATIVES INHIBITING BETA-SECRETASE ACTIVITY
    Publication number: 20100286145
    Abstract: The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease.
    Type: Application
    Filed: July 25, 2008
    Publication date: November 11, 2010
    Applicants: CoMentis, Inc., Purdue Research Foundation
    Inventors: Arun K. Ghosh, Chunfeng Liu, Thippeswamy Devasamudram, Hui Lei, Lisa M. Swanson, Sudha V. Ankala, John C. Lilly, Geoffrey M. Bilcer
  • Hydroxyethylene-based ?-secretase inhibitors and use thereof
    Patent number: 7659289
    Abstract: The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease.
    Type: Grant
    Filed: September 19, 2005
    Date of Patent: February 9, 2010
    Assignees: CoMentis, Inc., Oklahoma Medical Research Foundation, The Board of Trustees of the University of Illinois
    Inventors: Arun K. Ghosh, Hui Lei, Thippeswamy Devasamudram, Jordan J. N. Tang, Geoffrey M. Bilcer, Chunfeng Liu
  • Compounds which inhibit beta-secretase activity and methods of use
    Patent number: 7504420
    Abstract: The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating Alzheimer's disease.
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: March 17, 2009
    Assignees: CoMentis, Inc., The Board of Trustees of the University of Illinois, Oklahoma Medical Research Foundation, Purdue Research Foundation
    Inventors: Arun K. Ghosh, Nagaswamy Kumaragurubaran, Chunfeng Liu, Thippeswamy Devasamudram, Hui Lei, Lisa M. Swanson, Sudha V. Ankala, Jordan J. N. Tang, Geoffrey M. Bilcer
  • HIV protease inhibitors
    Patent number: 7157489
    Abstract: Compounds useful for inhibiting HIV protease are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating wild-type HIV and of multidrug-resistant strains of HIV, also are disclosed.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: January 2, 2007
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Arun K. Ghosh, Geoffrey M. Bilcer, Thippeswamy Devasamudram
  • HIV protease inhibitors
    Publication number: 20040039016
    Abstract: Compounds useful for inhibiting HIV protease are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating wild-type HIV and of multidrug-resistant strains of HIV, also are disclosed.
    Type: Application
    Filed: March 6, 2003
    Publication date: February 26, 2004
    Inventors: Arun K. Ghosh, Geoffrey M. Bilcer, Thippeswamy Devasamudram