Patents by Inventor Geoffrey M. Lynn

Geoffrey M. Lynn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Self-Assembling Nanoparticles Based On Amphiphilic Peptides
    Publication number: 20250127887
    Abstract: The present disclosure relates to a vaccine comprising an amphiphile having the formula S-[B]-[U]-H and at least one peptide antigen conjugate having the formula selected from [S]-[E1]-A-[E2]-[U]-H and H-[U]-[E1]-A-[E2]-[S], wherein the amphiphile and/or the at least one peptide antigen conjugate comprises a dendron amplifier. The vaccine is useful in treating or preventing a cancer, an autoimmune disease, an allergy, an infectious disease, a cardiovascular disease, or a neurodegenerative disease.
    Type: Application
    Filed: February 16, 2022
    Publication date: April 24, 2025
    Applicants: Barinthus Biotherapeutics North America, Inc., The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Geoffrey M. Lynn, Sarah R. Nichols, Vincent L. Coble, Andrew S. Ishizuka, Hugh Clarke Welles, Robert N. Goddu, Christopher Martin O’Brien Garliss, Ramiro Andrei Ramirez-Valdez
  • Self-Assembling Nanoparticles Based On Amphiphilic Peptides for Drug Delivery Applications
    Publication number: 20240382614
    Abstract: The present disclosure relates to a composition comprising a first amphiphile and optionally a second amphiphile each having the formula S-[B]-[U]-H-[D] and at least one drug molecule is noncovalently associated with or covalently bonded directly or via a suitable linker X1 to the first amphiphile and/or to the optional second amphiphile. The composition is useful in treating a cancer, an infectious disease or an inflammatory disease.
    Type: Application
    Filed: June 16, 2022
    Publication date: November 21, 2024
    Applicants: Barinthus Biotherapeutics North America, Inc., The United States of America, as Represented by the Secretary, Department of Health and Human Servic
    Inventors: Geoffrey M. Lynn, Yaling Zhu, Sarah R. Nichols, Qiuyin Ren, Andrew S. Ishizuka