Patents by Inventor Geoffrey N. Woodruff

Geoffrey N. Woodruff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cholecystokinin antagonists useful in the treatment of panic attcks
    Patent number: 5451602
    Abstract: Unnatural dipeptoids of .alpha.-substituted Try-Phe derivatives are useful as agents in the treatment of panic disorders. These dipeptoids are CCK.sub.B antagonists having utility in the prevention of panic attacks in patients prone to these attacks.
    Type: Grant
    Filed: February 2, 1994
    Date of Patent: September 19, 1995
    Assignee: Warner-Lambert Company
    Inventor: Geoffrey N. Woodruff
  • Pharmaceutical composition of 7-((substituted)amino-8-((substituted)carbonyl)-(methylamino)-1-oxasp iro(4,5)decanes and L-dopa
    Patent number: 5369120
    Abstract: A synergistic pharmaceutical composition of substituted phenoxy-, 1-, and 2-naphthalenyloxy-, indenyl-, indolyl-, benzo[b]furanyl-, and benzo[b]thienylcarboxamides of 7,8-(substituted-diamino)-1-oxaspiro[4.5]decanes and L-DOPA as a composition alleviating the symptoms of Parkinson's disease and/or dystonia. A method of using the pharmaceutical composition is also disclosed.
    Type: Grant
    Filed: July 28, 1993
    Date of Patent: November 29, 1994
    Assignee: Warner-Lambert Company
    Inventor: Geoffrey N. Woodruff
  • 7-((substituted)amino-8-((substitute d)carbonyl)-methylamino-1-oxaspiro(4,5)decanes useful in Parkinson's disease, dystonia, and other movement disorders
    Patent number: 5369105
    Abstract: Methods for using substituted phenoxy-, 1-, and 2-naphthalenyloxy-, indenyl-, indolyl-, benzo[b]furanyl-, and benzo[b]thienylcarboxamides of 7,8-(substituted-diamino)-1-oxaspiro[4.5]decanes as agents for alleviating the symptoms of Parkinson's disease, dystonia, and other movement disorders are disclosed. Pharmaceutical compositions employing the compounds are also disclosed.
    Type: Grant
    Filed: December 1, 1993
    Date of Patent: November 29, 1994
    Assignee: Warner-Lambert Company
    Inventors: Alexander McKnight, Geoffrey N. Woodruff
  • Cholecystokinin antagonists useful in the treatment of panic attacks
    Patent number: 5318981
    Abstract: Unnatural dipeptoids of .alpha.-substituted Try-Phe derivatives are useful as agents in the treatment of panic disorders. These dipeptoids are Cholecystokinin-B Receptor (CCK.sub.B) antagonists having utility in the prevention of panic attacks in patients prone to these attacks.
    Type: Grant
    Filed: March 17, 1993
    Date of Patent: June 7, 1994
    Assignee: Warner-Lambert Company
    Inventor: Geoffrey N. Woodruff
  • Cholecystokinin antagonists useful for treating depression
    Patent number: 5217957
    Abstract: The invention concerns cholecystokinin (CCK) antagonists useful in the treatment major and minor forms of depression. CCK-B, -A, and mixed -A and -B antagonists are useful. Especially useful are CCK.sub.B antagonists such as CI-988.
    Type: Grant
    Filed: August 20, 1991
    Date of Patent: June 8, 1993
    Assignee: Warner-Lambert Company
    Inventor: Geoffrey N. Woodruff
  • Cholecystokinin antagonists useful for treating depression
    Patent number: 5153191
    Abstract: The invention concerns cholecystokinin antagonists useful in the treatment major and minor forms of depression. Especially useful are CCK.sub.A antagonists such as devazepide and CCK.sub.B antagonists such as L-365,260 and LY262691.
    Type: Grant
    Filed: August 20, 1991
    Date of Patent: October 6, 1992
    Assignee: Warner-Lambert Company
    Inventor: Geoffrey N. Woodruff
  • Novel methods for treating neurodegenerative diseases
    Patent number: 5084479
    Abstract: The instant invention is novel uses of known cyclic amino acids. Such compounds as gabapentin are used for treating neurodegenerative disorders, perinatal asphyxia, status epilepticus, Alzheimer's Hungington's, Parkinson's, and Amyotrophic Lateral Sclerosis.
    Type: Grant
    Filed: November 23, 1990
    Date of Patent: January 28, 1992
    Assignee: Warner-Lambert Company
    Inventor: Geoffrey N. Woodruff
  • Use of specific N-methyl-D-aspartate receptor antagonists in the prevention and treatment of neurodegeneration
    Patent number: 4888347
    Abstract: Specific N-methyl-D-aspartate receptor antagonists are useful in the prevention and treatment of neurodegeneration in various pathological states.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: December 19, 1989
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Geoffrey N. Woodruff, Erik H. F. Wong, John A. Kemp