Patents by Inventor Geoffrey S. Baird

Geoffrey S. Baird has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescent protein variants and methods for making same
    Patent number: 7329735
    Abstract: The present invention relates generally to variant fluorescent proteins, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. The invention also relates to methods of making and using such fluorescent protein monomers and dimers.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: February 12, 2008
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Robert E. Campbell, Geoffrey S. Baird
  • Non-oligomerizing fluorescent proteins
    Patent number: 7022826
    Abstract: A non-oligomerizing fluorescent protein, which is derived from a fluorescent protein having at least one mutation that reduces or eliminates the ability of the fluorescent protein to oligomerize, is provided. The non-oligomerizing fluorescent protein can be derived from a naturally occurring green fluorescent protein, a red fluorescent protein, or other fluorescent protein, or a fluorescent protein related thereto. Also provided is a fusion protein, which includes a non-oligomerizing fluorescent protein linked to at least one polypeptide of interest. In addition, a polynucleotide encoding a non-oligomerizing fluorescent protein is provided, as is a recombinant nucleic acid molecule, which includes polynucleotide encoding a non-oligomerizing fluorescent protein operatively linked to at least a second polynucleotide.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: April 4, 2006
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, David A. Zacharias, Geoffrey S. Baird
  • Fluorescent protein variants and methods for making same
    Patent number: 7005511
    Abstract: The present invention relates generally to variant fluorescent proteins, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. The invention also relates to methods of making and using such fluorescent protein monomers and dimers.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: February 28, 2006
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Robert E. Campbell, Geoffrey S. Baird
  • Non-oligomerizing fluorescent proteins
    Publication number: 20030170911
    Abstract: A non-oligomerizing fluorescent protein, which is derived from a fluorescent protein having at least one mutation that reduces or eliminates the ability of the fluorescent protein to oligomerize, is provided. The non-oligomerizing fluorescent protein can be derived from a naturally occurring green fluorescent protein, a red fluorescent protein, or other fluorescent protein, or a fluorescent protein related thereto. Also provided is a fusion protein, which includes a non-oligomerizing fluorescent protein linked to at least one polypeptide of interest. In addition, a polynucleotide encoding a non-oligomerizing fluorescent protein is provided, as is a recombinant nucleic acid molecule, which includes polynucleotide encoding a non-oligomerizing fluorescent protein operatively linked to at least a second polynucleotide.
    Type: Application
    Filed: February 26, 2001
    Publication date: September 11, 2003
    Inventors: Roger Y. Tsien, David A. Zacharias, Geoffrey S. Baird