Abstract: Disclosed herein are small molecule GIP/GLP-1 dual receptor agonist compositions, pharmaceutical compositions, the use and preparation thereof.

Abstract: Disclosed herein are small molecule GIP/GLP-1 dual receptor agonist compositions. pharmaceutical compositions. the use and preparation thereof.

Abstract: A method of producing sialyloligosaccharides a sialyloligosaccharides-containing source that also contains carbohydrates and minerals. The process includes subjecting the source to a temperature of from about 67° C. and (i) filtration with a heat-resistant filter at a temperature of about 35 to about 95° C. to produce a first retentate and first permeate, or (ii) centrifugal separation to produce a light phase and a heavy phase and filtration of the light phase at a temperature of about 50 to about 70° C. to produce a first retentate and first permeate, (b) nanofiltration of the first permeate, or nanofiltration and diafiltration of the first permeate, to produce a second retentate and second permeate, and (c) concentration of the second retentate, to produce a sialyloligosaccharide-containing extract.

Abstract: An embodiment of the present invention relates to an aqueous solvent solution for absorbing carbon dioxide, and a process using an aqueous solvent solution for absorbing carbon dioxide. The aqueous solvent solution having a catalytic compound dissolved in the water that is an alkali salt of an N-substituted amino acid and at least one base that is dissolved in water. The catalytic compound assisting in forming a bicarbonate.

Abstract: A method of producing sialyloligosaccharides a sialyloligosaccharides-containing source that also contains carbohydrates and minerals. The process includes subjecting the source to a temperature of from about 67° C. and (i) filtration with a heat-resistant filter at a temperature of about 35 to about 95° C. to produce a first retentate and first permeate, or (ii) centrifugal separation to produce a light phase and a heavy phase and filtration of the light phase at a temperature of about 50 to about 70° C. to produce a first retentate and first permeate, (b) nanofiltration of the first permeate, or nanofiltration and diafiltration of the first permeate, to produce a second retentate and second permeate, and (c) concentration of the second retentate, to produce a sialyloligosaccharide-containing extract.

Abstract: A method of producing sialyloligosaccharides a sialyloligosaccharides-containing source that also contains carbohydrates and minerals. The process includes subjecting the source to a temperature of from about 67° C. and (i) filtration with a heat-resistant filter at a temperature of about 35 to about 95° C. to produce a first retentate and first permeate, or (ii) centrifugal separation to produce a light phase and a heavy phase and filtration of the light phase at a temperature of about 50 to about 70° C. to produce a first retentate and first permeate, (b) nanofiltration of the first permeate, or nanofiltration and diafiltration of the first permeate, to produce a second retentate and second permeate, and (c) concentration of the second retentate, to produce a sialyloligosaccharide-containing extract.

Abstract: An instrument monitoring apparatus includes a guide and sensing component configured to be attached to an ultrasound probe. The guide and sensing component includes a source of illumination configured to project a light beam into a light plane; and a light receiver aligned with the light plane and configured to quantify an amount of light reflected from an object in the light plane to the light receiver by receiving the amount of reflected light and converting it to an electrical signal. A control component includes a processor configured to receive the electrical signal from the light receiver, and based on a magnitude of the amount of light represented by the electrical signal, determine whether the object is sufficiently within the light plane. The processor instructs output of a first signal when it is determined that the object is sufficiently within the light plane.

Abstract: The cooler is very efficient at keeping certain food items cooler or at least partially frozen. The standard cooler is ideal for boating trips, camping trips and has been in existence for many years. The one drawback is that as the ice melts in the cooler, food items may become soggy and it is not desirable to store items such as cell phones in a cooler because of the danger of water exposure. With the application a drop liner is incorporated into the cooler that will provide the benefits of the cooler while at the same time allow personal items to be stored in the cooler. The drop liner is removable for easy cleaning.

Abstract: A method of producing sialyloligosaccharides a sialyloligosaccharides-containing source that also contains carbohydrates and minerals. The process includes subjecting the source to a temperature of from about 67° C. and (i) filtration with a heat-resistant filter at a temperature of about 35 to about 95° C. to produce a first retentate and first permeate, or (ii) centrifugal separation to produce a light phase and a heavy phase and filtration of the light phase at a temperature of about 50 to about 70° C. to produce a first retentate and first permeate, (b) nanofiltration of the first permeate, or nanofiltration and diafiltration of the first permeate, to produce a second retentate and second permeate, and (c) concentration of the second retentate, to produce a sialyloligosaccharide-containing extract.

Abstract: An instrument monitoring apparatus includes a guide and sensing component configured to be attached to an ultrasound probe. The guide and sensing component includes a source of illumination configured to project a light beam into a light plane; and a light receiver aligned with the light plane and configured to quantify an amount of light reflected from an object in the light plane to the light receiver by receiving the amount of reflected light and converting it to an electrical signal. A control component includes a processor configured to receive the electrical signal from the light receiver, and based on a magnitude of the amount of light represented by the electrical signal, determine whether the object is sufficiently within the light plane. The processor instructs output of a first signal when it is determined that the object is sufficiently within the light plane.

Abstract: The present invention relates to a process and plant for removing acid gases such as carbon dioxide, sulphur containing compounds and nitrogen containing compounds from gas streams including high and low pressure gas streams. A solvent solution containing alkali carbonates absorbs the acid gases including carbon dioxide and either one or both of sulphur and/or nitrogen containing compounds. The bicarbonate is regenerated into a carbonate form to provide a gas stream rich in carbon dioxide, and sulphur and/or nitrogen containing compounds are recovered.

Abstract: A power-generating system using sea current and sea anchors provides a constant source of renewable clean energy. The device will not disturb the environment and have relatively low maintenance requirements. The device will not disturb the flow of traffic on rivers and will not interfere with maritime activities. The system will also be self contained so that it will be relatively easy to move the device, if needed in the event of extremely inclement weather conditions.

Abstract: This device will generate electric power using wind current as long as the wind is sufficient to inflate and move a chute to a predetermined point. The chute is then inverted and retrieved by the device to start the cycle of inflation over again. The device will enable the generation of power that is reusable and clean and environmentally friendly.

Abstract: The present invention relates to a process and plant for removing acid gases such as carbon dioxide, sulphur containing compounds and nitrogen containing compounds from gas streams including high and low pressure gas streams. A solvent solution containing alkali carbonates absorbs the acid gases including carbon dioxide and either one or both of sulphur and/or nitrogen containing compounds. The bicarbonate is regenerated into a carbonate form to provide a gas stream rich in carbon dioxide, and sulphur and/or nitrogen containing compounds are recovered.

Abstract: This is a device that will allow an individual to remotely control the operation of a windshield wiper and/or a squeegee arm and blade independently of each other. It will be secured in a variety of methods to a window pane or window surface for the purpose of cleaning the window pane so that the individual may obtain maximum visibility. It will also be portable and light weight.

Abstract: In order to make it easier to use a garbage can, a self-bagging mechanism is placed in the bottom of the garbage can with an opening provided for a plurality of bags to be placed within a housing. The empty bags will be taken from the housing and will provide garbage bags to the trash cans at all times. The bag holder is designed to be refillable.

Abstract: Techniques for producing and supplying various voltage levels within a memory system having multiple memory blocks (e.g., memory chips) are described. The various voltage levels can be produced by voltage generation circuitry (e.g., charge pump and/or regulator circuitry) within the memory system. The various voltage levels can be supplied to the multiple memory blocks through a power bus. According to one aspect, charge pump and/or regulator circuits are provided within at most one of the memory blocks of a memory system (unless back-ups are provided for fault tolerance), and a power bus is used to distribute the generated voltage levels to other of the memory blocks. According to another aspect, a memory controller generates multiple supply voltage levels that are distributed (e.g., via a power bus) to each of the memory blocks.

Abstract: Techniques for producing and supplying various voltage levels within a memory system having multiple memory blocks (e.g., memory chips) are described. The various voltage levels can be produced by voltage generation circuitry (e.g., charge pump and/or regulator circuitry) within the memory system. The various voltage levels can be supplied to the multiple memory blocks through a power bus. According to one aspect, charge pump and/or regulator circuits are provided within at most one of the memory blocks of a memory system (unless back-ups are provided for fault tolerance), and a power bus is used to distribute the generated voltage levels to other of the memory blocks. According to another aspect, a memory controller generates multiple supply voltage levels that are distributed (e.g., via a power bus) to each of the memory blocks.

Abstract: A phosphate feed is separated into an enriched phosphate fraction and a waste aqueous stream which includes recoverable phosphate feed particles in an aqueous clay slime and which is flowed along a flow passage through a settling zone (where recoverable phosphate feed is recovered) into a quiescent sedimentation area where the slime settles, and water soluble polymeric flocculant for the slime is added to the aqueous stream to promote settling of the phosphate feed particles substantially without settling of slime in the settling zone and to accelerate sedimentation of flocculated slime in the sedimentation zone.