Patents by Inventor Geoffrey Symonds

Geoffrey Symonds has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for genetic modification of hematopietic progenitor cells and uses of the modified cells
    Publication number: 20080044394
    Abstract: Described are compositions and methods relating to gene therapy, particularly as applied to hematopoietic progenitor (HP) cells, to transduced cells and methods of obtaining them, and to methods of using them to provide prolonged engraftment of modified hematopoietic cells in human subjects. The invention particularly relates to ex vivo gene therapy of HP cells for treatment or prevention of HIV infection.
    Type: Application
    Filed: August 18, 2006
    Publication date: February 21, 2008
    Inventors: Geoffrey Symonds, Rafael Amado, Lun-Quan Sun, Janet MacPherson, Gregory Fanning, Wayne Gerlach
  • Means of producing and utilising a population of disease specific cytotoxic t-lymphocytes
    Publication number: 20060051866
    Abstract: The present invention relates to the production of a population of virus-specific CTLs in which the population contains an anti-virus specific gene expression construct. This population can be combined with a population of CD4+ T lymphocytes or a population of CD34+ hematopoietic progenitor cells and one or more of these populations of cells can be delivered to an autologous virus-positive individual. The present invention also relates to therapeutic cell products and to methods of treating diseases, particularly infectious diseases.
    Type: Application
    Filed: November 7, 2003
    Publication date: March 9, 2006
    Inventors: Geoffrey Symonds, Susan Pond, Gregory Fanning
  • Production of transduced hematopoietic progenitor cells
    Publication number: 20030082158
    Abstract: The present invention relates to a method for introducing exogenous nucleic acid-containing hematopoietic progenitor cells into a patient.
    Type: Application
    Filed: July 10, 2002
    Publication date: May 1, 2003
    Inventors: Geoffrey Symonds, John Murray, Gregory Fanning, Janet MacPherson, Susan Pond