Patents by Inventor Geoffrey TREGEAR

Geoffrey TREGEAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8841254
    Abstract: Human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues having a modified A chain and/or a modified B chain are described. Also described are nucleic acid sequences encoded human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues. Also described are methods for the treatment of conditions responsive to administration of H3 relaxin or analogues thereof.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: September 23, 2014
    Assignee: Howard Florey Institute of Experimental Physiology and Medicine
    Inventors: Geoffrey Tregear, Ross Alexander David Bathgate, Chrishan Surendran Samuel, Tanya Christine Burazin, Andrew Lawrence Gundlach, John Desmond Wade
  • Publication number: 20090239805
    Abstract: Human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues having a modified A chain and/or a modified B chain are described. Also described are nucleic acid sequences encoded human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues. Also described are methods for the treatment of conditions responsive to administration of H3 relaxin or analogues thereof.
    Type: Application
    Filed: March 27, 2009
    Publication date: September 24, 2009
    Inventors: Geoffrey TREGEAR, Ross Alexander David BATHGATE, Chrishan Surendran SAMUEL, Tanya Christine Burazin, Andrew Lawrence Gundlach, John Desmond Wade
  • Publication number: 20080176795
    Abstract: Human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues having a modified A chain and/or a modified B chain are described. Also described are nucleic acid sequences encoded human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues. Also described are methods for the treatment of conditions responsive to administration of H3 relaxin or analogues thereof.
    Type: Application
    Filed: August 21, 2007
    Publication date: July 24, 2008
    Inventors: Geoffrey Tregear, Ross Alexander David Bathgate, Chrishan Surendran Samuel, Tanya Christine Burazin, Andrew Lawrence Gundlach, John Desmond Wade
  • Publication number: 20060264367
    Abstract: A method for treating cardiac fibrosis resulting from injury of a mammalian heart is described comprising the step of contacting a therapeutically effective amount of relaxin and/or an LGR7 activating agent with cardiac cells following the injury in an amount sufficient to reduce the fibrosis. Also described are methods for protecting the heart following an ischemic event, inhibiting the proliferation of activated fibroblasts and antagonising collagen secretion or deposition in a mammalian heart.
    Type: Application
    Filed: May 21, 2005
    Publication date: November 23, 2006
    Applicants: Howard Florey Institute, Baker Medical Research Institute
    Inventors: Chrishan Samuel, Ross Alexander Bathgate, Geoffrey Tregear, Xiao-Jun Du
  • Publication number: 20050026822
    Abstract: Human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues having a modified A chain and/or a modified B chain are described. Also described are nucleic acid sequences encoded human H3 preprorelaxin, human H3 prorelaxin, human H3 relaxin, human relaxin analogues. Also described are methods for the treatment of conditions responsive to administration of H3 relaxin or analogues thereof.
    Type: Application
    Filed: October 2, 2002
    Publication date: February 3, 2005
    Applicant: AstraZeneca AB
    Inventors: Geoffrey Tregear, Ross Alexander Bathgate, Chrishan Samuel, Tanya Burazin, Andrew Gundlach, John Wade