Patents by Inventor Geoffrey Vince
Geoffrey Vince has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7927275Abstract: A system and method is provided for substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. Specifically, a data-gathering device is adapted to acquire heartbeat data and blood-vessel data from a heart-monitoring device and a data-gathering probe, respectively. In a preferred embodiment of the present invention, the blood-vessel data is acquired during a cyclical portion of the heartbeat data. By identifying a cyclical (or commonly reoccurring) portion of the heartbeat data and acquiring blood-vessel data during this cyclical portion (or during an interval that substantially corresponds thereto), the blood vessel can be analyzed as if it were standing still—i.e., not expanding and relaxing. In one embodiment of the present invention, the heart-monitoring device includes an EKG device, the data-gathering device includes an intra-vascular ultrasound (IVUS) device and a computing device, and the data-gathering probe includes at least one transducer.Type: GrantFiled: August 25, 2003Date of Patent: April 19, 2011Assignee: The Cleveland Clinic FoundationInventors: Barry D. Kuban, Jon D. Klingenamith, D. Geoffrey Vince, Anuja Nair
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Publication number: 20110087101Abstract: A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter (including components attached thereto—e.g., IVUS console, transducer, etc.). Specifically, in accordance with a first embodiment of the present invention, a computing device is electrically connected to a catheter and used to acquire RF backscattered data from a vascular structure (e.g., a blood vessel, etc.). The backscattered ultrasound data is then used, together with an algorithm, to estimate the transfer function. The transfer function can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i.e., the tissue component of the backscattered ultrasound data). In a second embodiment of the present invention, an IVUS console is electrically connected to a catheter and a computing device and is used to acquire RF backscattered data from a vascular structure.Type: ApplicationFiled: September 9, 2010Publication date: April 14, 2011Applicant: Volcano CorporationInventors: Anuja Nair, D. Geoffrey Vince, Jon D. Klingensmith, Barry D. Kuban
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Patent number: 7899224Abstract: A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image.Type: GrantFiled: June 1, 2006Date of Patent: March 1, 2011Assignee: The Cleveland Clinic CorporationInventors: Anuja Nair, D. Geoffrey Vince, Jon D. Klingensmith, Barry D. Kuban
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Patent number: 7874990Abstract: A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter (including components attached thereto—e.g., IVUS console, transducer, etc.). Specifically, in accordance with a first embodiment of the present invention, a computing device is electrically connected to a catheter and used to acquire RF backscattered data from a vascular structure (e.g., a blood vessel, etc.). The backscattered ultrasound data is then used, together with an algorithm, to estimate the transfer function. The transfer function can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i.e., the tissue component of the backscattered ultrasound data). In a second embodiment of the present invention, an IVUS console is electrically connected to a catheter and a computing device and is used to acquire RF backscattered data from a vascular structure.Type: GrantFiled: January 14, 2004Date of Patent: January 25, 2011Assignee: The Cleveland Clinic FoundationInventors: Anuja Nair, D. Geoffrey Vince, Jon D. Klingensmith, Barry D. Kuban
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Publication number: 20100331695Abstract: A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image.Type: ApplicationFiled: September 3, 2010Publication date: December 30, 2010Applicant: VOLCANO CORPORATIONInventors: Anuja Nair, David Geoffrey Vince, Marja Pauliina Margolis, Kendall Rand Waters
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Patent number: 7789834Abstract: A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image.Type: GrantFiled: March 21, 2007Date of Patent: September 7, 2010Assignee: Volcano CorporationInventors: Anuja Nair, David Geoffrey Vince, Marja Paulina Margolis, Kendall Rand Waters
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Patent number: 7627156Abstract: A system and method are disclosed for automatically classifying plaque lesions. A plaque classification application applies a plaque classification criterion to at least one graphical image, comprising a map of spectrally-analyzed characterized tissue of a vessel cross-section, to render an overall plaque classification for the slice or set of slices, covering a 3D volume. The plaque classification is based upon the amount and location of each characterized tissue type (e.g., necrotic core—NC). In an exemplary embodiment the set of potential plaque classifications, not to be confused with characterized tissue types—from which the plaque classifications are derived—include, for example: adaptive intimal thickening (AIT), pathological intimal thickening (PIT), fibroatheroma (FA), thin-cap fibroatheroma (TCFA), and fibro-calcific (FC).Type: GrantFiled: March 22, 2007Date of Patent: December 1, 2009Assignee: Volcano CorporationInventors: Marja Pauliina Margolis, D. Geoffrey Vince, Anuja Nair, Vincent J. Burgess
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Patent number: 7463759Abstract: A system and method use the frequency spectrum of a radio frequency (RF) signal backscattered from vascular tissue to identify at least one border on a vascular image. A data gathering device is connected to a computing device and a transducer via a catheter. RF data generated via the transducer is provided to the computing device via the data-gathering device. The computing device includes: at least one data storage device for storing a plurality of tissue types and parameters related thereto, and at least one application (e.g., a characterization application, a gradient-border application, a frequency-border application and/or an active-contour application). The characterization application converts the RF data into the frequency domain and identifies a plurality of associate parameters. The identified parameters are compared to the parameters stored in the data storage device to identify the corresponding tissue type and thereafter determine at least one border on a vascular image.Type: GrantFiled: June 8, 2006Date of Patent: December 9, 2008Assignee: The Cleveland Clinic FoundationInventors: Jon D. Klingensmith, Anuja Nair, Barry D. Kuban, D. Geoffrey Vince
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Publication number: 20080287795Abstract: A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. Specifically, in one embodiment of the present invention, an-IVUS console is electrically connected to a computing device and adapted to acquire IVUS data. The IVUS data (or multiple sets thereof) is then provided to (or acquired by) the computing device. In one embodiment of the present invention, the computing device includes a plurality of applications operating thereon—i.e., a border-detection application, an extrapolation application, and an active-contour application. These applications are used to (i) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e.Type: ApplicationFiled: April 14, 2008Publication date: November 20, 2008Applicant: Volcano CorporationInventors: Jon D. Klingensmith, D. Geoffrey Vince, Anuja Nair, Barry D. Kuban
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Publication number: 20080234582Abstract: A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image.Type: ApplicationFiled: March 21, 2007Publication date: September 25, 2008Applicant: Volcano CorporationInventors: Anuja Nair, David Geoffrey Vince, Marja Pauliina Margolis, Kendall Rand Waters
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Patent number: 7359554Abstract: A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. Specifically, in one embodiment of the present invention, an IVUS console is electrically connected to a computing device and adapted to acquire IVUS data. The IVUS data (or multiple sets thereof) is then provided to (or acquired by) the computing device. In one embodiment of the present invention, the computing device includes a plurality of applications operating thereon—i.e., a border-detection application, an extrapolation application, and an active-contour application. These applications are used to (i) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e.Type: GrantFiled: August 26, 2003Date of Patent: April 15, 2008Assignee: Cleveland Clinic FoundationInventors: Jon D. Klingensmith, D. Geoffrey Vince, Anuja Nair, Barry D. Kuban
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Patent number: 7215802Abstract: A system and method is provided for using the frequency spectrum of a radio frequency (RF) signal backscattered from vascular tissue to identify at least one border (e.g., tissue interface, etc.) on a vascular image. Embodiments of the present invention operate in accordance with a data gathering device (e.g., an intra-vascular ultrasound (IVUS) device, etc.) electrically connected to a computing device and a transducer via a catheter. The transducer is used to gather radio frequency (RF) data backscattered from vascular tissue. The RF data is then provided to (or acquired by) the computing device via the data-gathering device. In one embodiment of the present invention, the computing device includes (i) at least one data storage device (e.g., database, memory, etc.) for storing a plurality of tissue types and parameters related thereto and (ii) at least one application (e.g., a characterization application, a gradient-border application, a frequency-border application and/or an active-contour application).Type: GrantFiled: April 29, 2004Date of Patent: May 8, 2007Assignee: The Cleveland Clinic FoundationInventors: Jon D. Klingensmith, Anuja Nair, Barry D. Kuban, D. Geoffrey Vince
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Patent number: 7175597Abstract: One embodiment of the present system and method is directed to the identification of tissues within a vascular object by analyzing ultrasound data collected from the vascular object by non-invasive scans. By identifying and characterizing types of tissue from ultrasound data, an assessment can be made about the health condition of a patient without an invasive procedure. Other applications of the present system will also be appreciated including identifying other types of tissues.Type: GrantFiled: February 3, 2003Date of Patent: February 13, 2007Assignee: Cleveland Clinic FoundationInventors: D. Geoffrey Vince, Anuja Nair, Jon D. Klingensmith
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Patent number: 7074188Abstract: A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image.Type: GrantFiled: August 25, 2003Date of Patent: July 11, 2006Assignee: The Cleveland Clinic FoundationInventors: Anuja Nair, D. Geoffrey Vince, Jon D. Klingensmith, Barry D. Kuban
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Publication number: 20040152983Abstract: One embodiment of the present system and method is directed to the identification of tissues within a vascular object by analyzing ultrasound data collected from the vascular object by non-invasive scans. By identifying and characterizing types of tissue from ultrasound data, an assessment can be made about the health condition of a patient without an invasive procedure. Other applications of the present system will also be appreciated including identifying other types of tissues.Type: ApplicationFiled: February 3, 2003Publication date: August 5, 2004Inventors: D. Geoffrey Vince, Anuja Nair, Jon D. Klingensmith
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Publication number: 20040122326Abstract: A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image.Type: ApplicationFiled: August 25, 2003Publication date: June 24, 2004Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Anuja Nair, D. Geoffrey Vince, Jon D. Klingonamith, Barry D. Kuban
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Publication number: 20040037455Abstract: A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. Specifically, in one embodiment of the present invention, an IVUS console is electrically connected to a computing device and adapted to acquire IVUS data. The IVUS data (or multiple sets thereof) is then provided to (or acquired by) the computing device. In one embodiment of the present invention, the computing device includes a plurality of applications operating thereon—i.e., a border-detection application, an extrapolation application, and an active-contour application. These applications are used to (i) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e.Type: ApplicationFiled: August 26, 2003Publication date: February 26, 2004Inventors: Jon D. Klingensmith, D. Geoffrey Vince, Anuja Nair, Barry D. Kuban
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Publication number: 20040039286Abstract: A system and method is provided for substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. Specifically, a data-gathering device is adapted to acquire heartbeat data and blood-vessel data from a heart-monitoring device and a data-gathering probe, respectively. In a preferred embodiment of the present invention, the blood-vessel data is acquired during a cyclical portion of the heartbeat data. By identifying a cyclical (or commonly reoccurring) portion of the heartbeat data and acquiring blood-vessel data during this cyclical portion (or during an interval that substantially corresponds thereto), the blood vessel can be analyzed as if it were standing still—i.e., not expanding and relaxing. In one embodiment of the present invention, the heart-monitoring device includes an EKG device, the data-gathering device includes an intra-vascular ultrasound (IVUS) device and a computing device, and the data-gathering probe includes at least one transducer.Type: ApplicationFiled: August 25, 2003Publication date: February 26, 2004Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Barry D. Kuban, Jon D. Klingenamith, D. Geoffrey Vince, Anuja Nair
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Patent number: 6381350Abstract: An intravascular ultrasound (IVUS) analysis system and method is provided which determines luminal and medial-adventitial boundaries of a blood vessel. Ultrasonic data is acquired by a rotating transducer mounted to a tip of a catheter which is inserted into the blood vessel. An intravascular image is reconstructed from the ultrasound data. To determine the luminal boundary of a vessel, a user selects boundary points on the image believed to be locations of the luminal boundary. A boundary contour is generated based on the boundary points. The boundary contour is then optimized by adjusting the boundary points based on a radially determined edge of the luminal boundary performed on the image in polar format. Once the final luminal boundary contour is generated, the process is repeated to determine the medial-adventitial boundary contour. With the contour data, properties of the blood vessel are analyzed including determining the area of the lumen and percent of occlusion caused by plaque.Type: GrantFiled: July 2, 1999Date of Patent: April 30, 2002Assignee: The Cleveland Clinic FoundationInventors: Jon D. Klingensmith, David Geoffrey Vince, Raj Shekhar
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Patent number: 6200268Abstract: A method and system for characterizing plaque components within a vascular object is provided. The vascular object is scanned with an ultrasonic device and backscatter signal data is collected. Histology images are prepared and digitized which correspond to the scanned vascular sections. A plaque component is selected on the histology image and its coordinates are mapped to a corresponding location on an IVUS image constructed from the backscatter signal. The IVUS image location is then translated to the corresponding signal section of the raw backscatter signal. Frequency analysis is performed on the signal section to determine its signal properties. The signal properties are correlated to the selected plaque component of the histology image and stored in a plaque characterization database. The process is then repeated for all plaque components and other tissue types found within the vascular object and stored in the database.Type: GrantFiled: September 10, 1999Date of Patent: March 13, 2001Assignee: The Cleveland Clinic FoundationInventors: D. Geoffrey Vince, Barry D. Kuban, Anuja Nair