Patents by Inventor Geoffrey W. de Lisle

Geoffrey W. de Lisle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mycobacteria virulence factors and a novel method for their identification
    Patent number: 5783386
    Abstract: Polynucleotides associated with virulence in mycobacteria, and particularly a fragment of DNA isolated from M. bovis that contains a region encoding a putative sigma factor. Also provided are methods for a DNA sequence or sequences associated with virulence determinants in mycobacteria, and particularly in M. tuberculosis and M. bovis. The invention also provides corresponding polynucleotides associated with avirulence in mycobacteria. In addition, the invention provides a method for producing strains with altered virulence or other properties which can themselves be used to identify and manipulate individual genes.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: July 21, 1998
    Assignees: Agresearch, New Zealand Pastoral Agriculture Research Institute Ltd., Albert Einstein College of Medicine of Yeshiva University
    Inventors: William R. Jacobs, Jr., Barry R. Bloom, Desmond Michael Collins, Geoffrey W. de Lisle, Lisa Pascopella, Riku Pamela Kawakami