Patents by Inventor Geoffry L. Curran

Geoffry L. Curran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide-Mediated Non-Covalent Delivery of Active Agents Across the Blood-Brain Barrier
    Publication number: 20190322723
    Abstract: The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In some cases, such transport may increase the effectiveness of the biological molecules or imaging agents.
    Type: Application
    Filed: July 3, 2019
    Publication date: October 24, 2019
    Inventors: Geoffry L. Curran, Gobinda Sarkar, Joseph F. Poduslo, Robert B. Jenkins, Val J. Lowe, Eric W. Mahlum
  • Peptide-mediated non-covalent delivery of active agents across the blood-brain barrier
    Patent number: 10377813
    Abstract: The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In some cases, such transport may increase the effectiveness of the biological molecules or imaging agents.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: August 13, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Geoffry L. Curran, Gobinda Sarkar, Joseph F. Poduslo, Robert B. Jenkins, Val J. Lowe, Eric W. Mahlum
  • PEPTIDE-MEDIATED DELIVERY OF IMMUNOGLOBULINS ACROSS THE BLOOD-BRAIN BARRIER
    Publication number: 20180340020
    Abstract: Provided herein are materials and methods for delivering immunoglobulins (e.g. therapeutic immunoglobulins) across the blood-brain barrier.
    Type: Application
    Filed: August 9, 2018
    Publication date: November 29, 2018
    Inventors: Gobinda Sarkar, Robert B. Jenkins, Geoffry L. Curran
  • Peptide-mediated delivery of immunoglobulins across the blood-brain barrier
    Patent number: 10072065
    Abstract: Provided herein are materials and methods for delivering immunoglobulins (e.g. therapeutic immunoglobulins) across the blood-brain barrier.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: September 11, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Gobinda Sarkar, Robert B. Jenkins, Geoffry L. Curran
  • Peptide-Mediated Non-Covalent Delivery of Active Agents Across the Blood-Brain Barrier
    Publication number: 20170145076
    Abstract: The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In some cases, such transport may increase the effectiveness of the biological molecules or imaging agents.
    Type: Application
    Filed: February 2, 2017
    Publication date: May 25, 2017
    Inventors: Geoffry L. Curran, Gobinda Sarkar, Joseph F. Poduslo, Robert B. Jenkins, Val J. Lowe, Eric W. Mahlum
  • Peptide-mediated non-covalent delivery of active agents across the blood-brain barrier
    Patent number: 9597408
    Abstract: The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In some cases, such transport may increase the effectiveness of the biological molecules or imaging agents.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: March 21, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Geoffry L. Curran, Gobinda Sarkar, Joseph F. Poduslo, Robert B. Jenkins, Val J. Lowe, Erik W. Mahlum
  • PEPTIDE-MEDIATED DELIVERY OF IMMUNOGLOBULINS ACROSS THE BLOOD-BRAIN BARRIER
    Publication number: 20170058017
    Abstract: Provided herein are materials and methods for delivering immunoglobulins (e.g. therapeutic immunoglobulins) across the blood-brain barrier.
    Type: Application
    Filed: August 24, 2016
    Publication date: March 2, 2017
    Inventors: Gobinda Sarkar, Robert B. Jenkins, Geoffry L. Curran
  • PEPTIDE-MEDIATED DELIVERY OF ACTIVE AGENTS ACROSS THE BLOOD-BRAIN BARRIER
    Publication number: 20170007669
    Abstract: Provided herein are methods for transporting an infectious agent (e.g., a virus) across the blood-brain barrier (BBB). For example, the methods provided herein can be used to make a non-human animal model of an infectious brain disease. In some embodiments, the methods provided herein can be used to make a mouse model of multiple sclerosis.
    Type: Application
    Filed: July 7, 2016
    Publication date: January 12, 2017
    Inventors: Gobinda Sarkar, Robert B. Jenkins, Geoffry L. Curran, Charles L. Howe, Reghann G. LaFrance-Corey
  • Peptide-Mediated Non-Covalent Delivery of Active Agents Across the Blood-Brain Barrier
    Publication number: 20140328866
    Abstract: The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In some cases, such transport may increase the effectiveness of the biological molecules or imaging agents.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 6, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Geoffry L. Curran, Gobinda Sarkar, Joseph F. Poduslo, Robert B. Jenkins, Val J. Lowe, Erik W. Mahlum
  • PEPTIDE-MEDIATED DELIVERY OF ACTIVE AGENTS ACROSS THE BLOOD-BRAIN BARRIER
    Publication number: 20140314663
    Abstract: Provided herein are methods for transporting an active agent (e.g., a therapeutic agent or an imaging agent) across the blood-brain barrier (BBB) in a patient. For example, the methods provided herein can be used to treat a brain disease in a patient, such as brain cancer. In some embodiments, the methods provided herein can be used to image the central nervous system of a patient.
    Type: Application
    Filed: November 29, 2012
    Publication date: October 23, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Gobinda Sarkar, Geoffry L. Curran, Robert B. Jenkins
  • PEPTIDE-MEDIATED NON-COVALENT DELIVERY OF ACTIVE AGENTS ACROSS THE BLOOD-BRAIN BARRIER
    Publication number: 20120107243
    Abstract: The peptides described herein can function as carrier peptides. These peptides can associate with (e.g., non-covalently bind) biologically active molecules or imaging agents to transport the biologically active molecules or imaging across the blood-brain barrier. In some cases, such transport may increase the effectiveness of the biological molecules or imaging agents.
    Type: Application
    Filed: July 14, 2010
    Publication date: May 3, 2012
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Geoffry L. Curran, Gobinda Sarkar, Joseph F. Poduslo, Robert B. Jenkins, Val J. Lowe, Eric W. Mahlum
  • Treatment for central nervous system disorders
    Patent number: 7988969
    Abstract: Compositions that include an A? polypeptide linked to a non-A? polypeptide are described, as well as methods of using such compositions.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: August 2, 2011
    Assignee: MAYO Foundation for Medical Education and Research
    Inventors: Joseph F. Poduslo, Geoffry L. Curran
  • Treatment for Central Nervous System Disorders
    Publication number: 20090324492
    Abstract: Compositions that include an A? polypeptide linked to a non-A? polypeptide are described, as well as methods of using such compositions.
    Type: Application
    Filed: August 31, 2009
    Publication date: December 31, 2009
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Joseph F. Poduslo, Geoffry L. Curran
  • Methods for detecting parenchymal plaques in vivo
    Publication number: 20090028789
    Abstract: Methods for detecting parenchymal plaque deposits in the brain of a living mammal are described that include administering a polyamine modified, labeled polypeptide having specific binding affinity for the extracellular deposit, to the living mammal. Isolated ?-amyloid peptides that are polyamine modified and labeled with a radioisotope or contrast agent also are described.
    Type: Application
    Filed: January 18, 2008
    Publication date: January 29, 2009
    Inventors: Joseph F. Poduslo, Geoffry L. Curran, Thomas M. Wengenack
  • Treatment for central nervous system disorders
    Publication number: 20040142872
    Abstract: Compositions that include an A&bgr; polypeptide linked to a non-A&bgr; polypeptide are described, as well as methods of using such compositions.
    Type: Application
    Filed: March 9, 2004
    Publication date: July 22, 2004
    Applicant: Mayo Foundation for Medical Education and Research ,a MN corporation
    Inventors: Joseph F. Poduslo, Geoffry L. Curran
  • Treatment for central nervous system disorders
    Publication number: 20030082191
    Abstract: Compositions that include an A&bgr; polypeptide linked to a non-A&bgr; polypeptide are described, as well as methods of using such compositions.
    Type: Application
    Filed: August 29, 2001
    Publication date: May 1, 2003
    Inventors: Joseph F. Poduslo, Geoffry L. Curran