Abstract: A glovebox air intake emergency safety shutoff system includes a glovebox; a first manual valve operatively connected to the glovebox, wherein the first manual valve articulates between an open position and a closed position; an automatic valve operatively connected to the manual valve, wherein the automatic valve articulates between an open position and a closed position; an air intake component that inputs air into the glovebox; an air exhaust component that discharges air from the glovebox; and a pressure monitor that detects a level of pressure in the glovebox. The pressure monitor includes a pressure sensor that measures a pressure in the glovebox and transmits a signal associated with the measured pressure; and a pressure controller that receives the signal and responds according to the measured pressure. The pressure controller operatively closes the automatic valve upon the measured pressure increasing above a predetermined limit.