Patents by Inventor Georg Arnold Krei

Georg Arnold Krei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spray drying of thrombin inhibitors
    Patent number: 6693120
    Abstract: The invention relates to a process for preparing constant-weight thrombin inhibitors of the formula I where n is 0, 1, 2, and tautomers thereof, wherein an aqueous solution of the active substance is spray dried.
    Type: Grant
    Filed: July 2, 2002
    Date of Patent: February 17, 2004
    Assignee: Abbott GmbH & Co. KG
    Inventors: Bernd Schaefer, Guido Harms, Hermann Ascherl, Georg Arnold Krei
  • Method for producing (+)-exo-6-phenyl-3-azabicyclo-[3.2.0]heptanes
    Patent number: 6328855
    Abstract: A process for preparing (+)-exo-6-phenyl-3-azabicyclo[3.2.0]heptanes of the formula I where R is hydrogen, chlorine, bromine, fluorine or methoxy, which comprises photocyclizing a bisallylammonium salt of the formula II where R has the meanings given above and X− is an anion, in an inert solvent in a glass apparatus with addition of sensitizer and precipitating using (−)-ditoluoyltartaric acid the desired (+)-exo-isomer I as ditoluoyltartrate from the resulting mixture, with or without recrystallization of this tartrate from an alcohol/water mixture.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: December 11, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Norbert Bischof, Ernst Buschmann, Michael Henningsen, Georg Arnold Krei, Rainer Munschauer, Thomas Pfeiffer, Gerd Steiner, Wolfgang Viergutz