Patents by Inventor Georg Berger
Georg Berger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20070122638Abstract: The invention relates to a method for the production of a metallic substrate having a biocompatible surface and to the substrate that is produced by means of said method. The method comprises treatment of a metal, i.e., Ti, Ti alloys with Al, V, Ta, Nb, Ni, Fe, Mo or mixtures thereof, Ta, Ta alloys with Fe, Al, Cr, stainless steel, with a melt of calcium nitrate and an additional component which is an oxygen salt of Na, K, Li, Mg and mixtures thereof, said treatment being effected at 180-480 ° C. for 0.1 to 12 hours. A substrate is obtained, wherein the overall layer thickness ranges from 10 to below 1600 nm and the fatigue strength of the substrate is in the same fatigue strength range as that of an untreated substrate at equal number of vibrations N.Type: ApplicationFiled: November 28, 2006Publication date: May 31, 2007Applicant: BAM Bundesanstalt fuer Materialforschung und-pruefungInventors: Georg Berger, Ute Ploska
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Patent number: 7223420Abstract: The present invention relates to a powder mixture for resorbable calcium phosphate biocements, which mixture consists of 40–99% by volume of powder having a particle size of 0.1–10 ?m, 1–20% by volume of powder having a particle size of 10–43 ?m and 0–59% by volume of powder having a particle size of 43–315 ?m, which powder is obtained by grinding the spontaneously crystallizing melts of a material comprising crystalline and X-ray amorphous phases, which material a) according to 31P-NMR measurements, contains Q0-groups of orthophosphate and Q1-groups of diphosphate, the orthophosphates or Q0-groups making up 65 to 99.9% by weight relative to the total phosphorus content of the powder mixture and the diphosphates or Q1-groups making up 0.1 to 35% by weight relative to the total phosphorus content of the powder mixture, and b) according to X-ray diffractometric measurements and relative to the total weight of the powder mixture, contains 35 to 99.Type: GrantFiled: October 20, 2003Date of Patent: May 29, 2007Assignee: BAM Bundesanstalt für Materialforschung und -prüfungInventors: Georg Berger, Heidi Marx, Christian Jäger, Jutta Pauli
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Patent number: 7223808Abstract: The invention relates to a method for the production of an adhesive and an adhesive kit for joining similar or different metal surfaces or ceramics, especially in the field of biomedicine. The objective of the invention is to avoid polymerization-linked by-products and disadvantageous effects, in addition to enabling a temporary biocompatible bond between metal and metal or metal and ceramics. The inventive method consist in using a monomer-free polymethylmethacrylate which is mixed with a suitable, non-toxic solvent and a bioactive vitreous-crystalline material with a particle size ranging from 0.05–20?, consisting of 15–45 wt. % CaO, 40–45 wt. % P2O5, 10–40 wt. % ZrO2 and 0.7–3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to an adhesive kit consisting of said components.Type: GrantFiled: June 14, 2002Date of Patent: May 29, 2007Assignees: Humboldt Universitaet Berlin Carite Universitaetsklinikum (CCM), Bam Bundesanstalt Fuer Materialforschung und -Pruefung, Vita Zahnfabrik H. Rauter GmbH & Co. KGInventors: Wolf-Dieter Müller, Georg Berger, Emil Nagel, Klaus-Peter Lange
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Patent number: 7148163Abstract: The present invention relates to a glass used as a sintering aid for a resorbable molded body containing calcium phosphate as well as to a method for manufacturing said molded body. According to the invention, the material is ?-tricalcium phosphate and the glass has a chemical composition of 68–78% by weight SiO2, 5–12% by weight MgO and 12–27% by weight Na2O. The aforesaid molded body is manufactured by melting said glass, grinding it until a grain size D50 of 0.7–2 ?m is achieved and mixing it with ?-tricalcium phosphate having a grain size D50 of 1–7.5 ?m, giving the mixture the desired shape and producing the molded body by sintering said mixture at between 1,150 and 1,350° C., wherein the grain size of ?-TCP must not be smaller than that of the glass.Type: GrantFiled: October 20, 2003Date of Patent: December 12, 2006Assignee: BAM Bundesanstalt fur Materialforschung und-prufungInventors: Georg Berger, Renate Gildenhaar, Andrea Spitzer
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Publication number: 20060265062Abstract: The invention relates to a resorbable, biocompatible moulded body and a process for its production. The moulded body is mechanically processable and comprises an organic component which is solid at <40° C., which is biocompatible, which forms networks in water, and which is resorbable in the bodies of mammals within 3 to 20 days, and a solid, inorganic chemical component which is distributed within it with a particle size of d50 of 7-800 nm, which is resorbable in the bodies of mammals within 7 to 180 days. This is obtained by converting a sol consisting of Ca compounds with an acidic phosphorous acid ester, contaminating the sol with additional cations by adding 0 to 5 weight % alcoholate or carboxylate of Na, K, Zn, Mg or mixtures of these, mixing the sol with the dissolved organic component, spray-drying the mixture and compressing the granulate obtained into a moulded body.Type: ApplicationFiled: May 17, 2006Publication date: November 23, 2006Applicant: BAM BUNDESANSTALT FUER MATERIALFORSCHUNG UND-PRUEFUNGInventors: Georg Berger, Gert Neumann
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Patent number: 7109254Abstract: A method for producing a bioactive bone cement and a bone cement kit for anchoring artificial joints and for filling out bone defects. The method avoids polymerization-linked by-products and disadvantageous effects, while at the same time providing the bone cement with long-term stability. The inventive method uses a monomer-free polymethylmethacrylate, which is mixed with a suitable non-toxic solvent, and a bioactive, vitreous-crystalline material with a particle size ranging from >20 to 200 ?m, having 15–45 wt. % CaO, 40–45 wt. % P2O5, 10–40 wt. % ZrO2 and 0.7–3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to a bone cement kit having said components.Type: GrantFiled: June 14, 2002Date of Patent: September 19, 2006Assignees: BAM Bundesanstalt fuer Materialforschung und - pruefung, Vita Zahnfabrik H. Rauter GmbH & Co. KG, Humboldt-Universitaet Berlin, Charite Universitaetsklinikum (CCM) Medizinische Fakultaet der Humbolt-UniversitaetInventors: Wolf-Dieter Müller, Emil Nagel, Georg Berger
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Patent number: 7104599Abstract: A folding table for the rear of a backrest, the table having a surface with a depression therein in which a carrier for visible material, like an advertisement, is disposed. The carrier is received in an undercut in the depression. Alternatively, a frame around the edge of the carrier has projections received in grooves in the table for holding the frame and thereby the carrier to the surface.Type: GrantFiled: May 8, 2003Date of Patent: September 12, 2006Assignees: E.I.S. Aircraft GmbHInventors: Georg Berger, Hans-Jörg Brandt
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Publication number: 20040235637Abstract: The present invention relates to a glass used as a sintering aid for a resorbable moulded body containing calcium phosphate as well as to a method for manufacturing said moulded body. According to the invention, the material is &bgr;-tricalcium phosphate and the glass has a chemical composition of 68-78% by weight SiO2, 5-12% by weight MgO and 12-27% by weight Na2O. The aforesaid moulded body is manufactured by melting said glass, grinding it until a grain size D50 of 0.7-2 &mgr;m is achieved and mixing it with &bgr;-tricalcium phosphate having a grain size D50 of 1-7.5 &mgr;m, giving the mixture the desired shape and producing the moulded body by sintering said mixture at between 1,150 and 1,350° C., wherein the grain size of &bgr;-TCP must not be smaller than that of the glass.Type: ApplicationFiled: October 20, 2003Publication date: November 25, 2004Inventors: Georg Berger, Renate Gildenhaar, Andrea Spitzer
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Publication number: 20040228927Abstract: The present invention relates to an X-ray amorphous-crystalline material with high solubility which can be used as a bioactive bone replacement material and as a substrate material in biotechnology. The new material comprising crystalline and X-ray amorphous phases is characterized in that according to 31P-NMR measurements, it contains Q0-groups of orthophosphate and Q1-groups of diphosphate, the ortho-phosphates or Q0-groups making up 70 to 99.9% by weight relative to the total phosphorus content of the finished material and the diphosphates or Q1-groups making up 0.1 to 30% by weight relative to the total phosphorus content of the finished material, and that according to X-ray diffractometric measurements and relative to the total weight of the finished material, 30 to 99.9% by weight of a main crystal phase consisting of Ca2K1−xNa1+x(PO4)2, where x=0.1 to 0.9, is contained in the bone replacement material and 0.Type: ApplicationFiled: October 20, 2003Publication date: November 18, 2004Inventors: Georg Berger, Andrea Spitzer, Christian Jager, Jutta Pauli, Renate Gildenhaar
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Publication number: 20040175409Abstract: The invention relates to a method for the production of an adhesive and an adhesive kit for joining similar or different metal surfaces or ceramics, especially in the field of biomedicine. The objective of the invention is to avoid polymerization-linked by-products and disadvantageous effects, in addition to enabling a temporary biocompatible bond between metal and metal or metal and ceramics. The inventive method consist in using a monomer-free polymethylmethacrylate which is mixed with a suitable, non-toxic solvent and a bioactive vitreous-crystalline material with a particle size ranging from 0.05-20&mgr;, consisting of 15-45 wt. % CaO, 40-45 wt. % P2O5, 10-40 wt. % ZrO2 and 0.7-3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to an adhesive kit consisting of said components.Type: ApplicationFiled: December 15, 2003Publication date: September 9, 2004Inventors: Wolf-Dieter Muller, Georg Berger, Emil Nagel, Klaus-Peter Lange
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Publication number: 20040175430Abstract: The present invention relates to a material with orthophosphate and having a high solubility which can be used as a bioactive bone replacement material and as a substrate material in biotechnology. According to 31P-NMR measurements, the new material comprises Q0-groups of orthophosphate and Q1-groups of diphosphate, the ortho-phosphates or Q0-groups making up 65 to 99.9% by weight relative to the total phosphorus content of the finished material and the diphosphates or Q1-groups making up 0.1 to 35% by weight relative to the total phosphorus content of the finished material, and wherein according to X-ray diffractometric measurements and relative to the total weight of the finished material, 35 to 99.9% by weight of a main crystal phase consisting of Ca10Na(PO4)7, Ca10K(PO4)7, mixtures thereof or mixed crystals according to the general formula Ca10KxNa1−x(PO4)7, where x=0 to 1, is contained in the bone replacement material and 0.Type: ApplicationFiled: October 20, 2003Publication date: September 9, 2004Inventors: Georg Berger, Andrea Spitzer, Christian Jager, Jutta Pauli, Renate Gildenhaar
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Publication number: 20040158330Abstract: The invention relates to a metallic implant, which has vitreous-crystalline bioactive material on the surface thereof. According to the invention, a metallic implant base body arranged on the surface of the particles has a bioactive, vitreous-crystalline material consisting of 15-45 wt. % CaO, 40-45 wt. % P2O5, 10-40 wt. % ZrO2 and 0.7-3.5 wt. % fluoride, having apatite and calcium zirconium phosphate as main crystalline and a glass phase as an auxiliary component. Said vitreous crystalline material contains at least 35 wt. % main crystal phases and at least 5-15 wt. % auxiliary compounds. All of the percentage data is expressed in relation to the total weight of the vitreous crystalline material and the particle size of the vitreous crystalline material is between 60-350 &mgr;m.Type: ApplicationFiled: December 15, 2003Publication date: August 12, 2004Inventors: Wolf-Dieter Mller, Georg Berger
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Patent number: 6767854Abstract: The invention refers to a material which is chemically long-term stable in a neutral or slightly acid environment and which can be used both as bioactive bone replacement material, e.g. in the form of a coating applied onto metallic prosthesis sticks by thermal spraying, and as substrate material in biotechnology, e.g. in the form of a ceramic sheet. According to the invention, said material comprises 15-45% by weight CaO, 40-45% by weight P2O5, 10-40% by weight ZrO2 and fluoride, said material further comprises two crystalline phases being apatite and calcium zirconium phosphate, and a secondary glass phase. Said material has a very high chemical long-term stability, compared to known materials which can also be produced by means of a melting process.Type: GrantFiled: June 13, 2002Date of Patent: July 27, 2004Assignee: Bam Bundesanstalt fuer Materialforschung und PrufungInventors: Georg Berger, Ute Ploska
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Publication number: 20040138759Abstract: The invention relates to a method for producing a bioactive bone cement and a bone cement kit for anchoring artificial joints and for filling out bone defects. The objective of the invention is to avoid polymerization-linked by-products and disadvantageous effects, while at the same time providing the bone cement with long-term stability. The inventive method consists in using a monomer-free polymethylmethacrylate which is mixed with a suitable non-toxic solvent, and a bioactive, vitreous-crystalline material with a particle size ranging from >20 to 200 &mgr;m, consisting of 15-45 wt. % CaO, 40-45 wt. % P2O5, 10-40 wt. % ZrO2 and 0.7-3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to a bone cement kit consisting of said components.Type: ApplicationFiled: December 15, 2003Publication date: July 15, 2004Inventors: Wolf-Dieter Muller, Emil Nagel, Georg Berger
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Publication number: 20040086545Abstract: The present invention relates to a powder mixture for resorbable calcium phosphate biocements, which mixture consists of 40-99% by volume of powder having a particle size of 0.Type: ApplicationFiled: October 20, 2003Publication date: May 6, 2004Inventors: Georg Berger, Heidi Marx, Christian Jager, Jutta Pauli
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Publication number: 20030217673Abstract: A folding table for the rear of a backrest, the table having a surface with a depression therein in which a carrier for visible material, like an advertisement, is disposed. The carrier is received in an undercut in the depression. Alternatively, a frame around the edge of the carrier has projections received in grooves in the table for holding the frame and thereby the carrier to the surface.Type: ApplicationFiled: May 8, 2003Publication date: November 27, 2003Applicant: E.I.S. Aircraft GmbH & Georg BergerInventors: Georg Berger, Hans-Jorg Brandt
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Publication number: 20020193230Abstract: The invention refers to a material which is chemically long-term stable in a neutral or slightly acid environment and which can be used both as bioactive bone replacement material, e.g. in the form of a coating applied onto metallic prosthesis sticks by thermal spraying, and as substrate material in biotechnology, e.g. in the form of a ceramic sheet. According to the invention, said material comprises 15-45% by weight CaO, 40-45% by weight P2O5, 10-40% by weight ZrO2 and fluoride, said material further comprises two crystalline phases being apatite and calcium zirconium phosphate, and a secondary glass phase. Said material has a very high chemical long-term stability, compared to known materials which can also be produced by means of a melting process.Type: ApplicationFiled: June 13, 2002Publication date: December 19, 2002Inventors: Georg Berger, Ute Ploska
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Patent number: 5338771Abstract: A composite socket of a joint endoprosthesis may be fashioned in which the inorganic component of the socket has apatite and/or wollastonite crystalline phases and additionally secondary crystalline phases providing improved hydrolysis stability. The inorganic mixture consists (in mass % proportions) of 31-34% CaO, 10-12% P.sub.2 O.sub.5, 43-46% SiO.sub.2, 3-5% Na.sub.2 O, 2-3% CaF.sub.2 and, beyond the 100% of the above components, also 0.5-11% Al.sub.2 O.sub.3 and/or Zr.sub.2 and Al.sub.2 O.sub.3 or TiO.sub.2 and ZrO.sub.2 or TiO.sub.2 and ZrO.sub.2 and Al.sub.2 O.sub.3, whereby the proportion of TiO.sub.2 lies between 0.5 and 5%. Essential to the invention, too, is a certain grain size distribution and radius of aperture between the ball and the socket. The result is non-wearing operation of the endoprosthesis.Type: GrantFiled: July 28, 1992Date of Patent: August 16, 1994Assignee: Eska Medical Luebeck Medizin Technik GmbHInventors: Gerd Neumann, Peter Hutschenreuther, Willfried Glien, Dagmar Raab, Barbara Leuner, Gabriele Steinborn, Georg Berger