Patents by Inventor Georg Feldmann

Georg Feldmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8715741
    Abstract: Polymeric nanoparticles with a hydrophobic core and a hydrophilic shell are formed from: 1) N-isopropylacrylamide (NIPAAM), at a molar ratio of about 50% to about 90%, and preferably 60% for specific delivery routes such as oral or parenteral; either water-soluble vinyl derivatives like vinylpryolidone (VP) or vinyl acetate (VA), or water insoluble vinyl derivatives like methyl methacrylate (MMA) or styrene (ST), at a molar ratio of about 10% to about 30%; and acrylic acid (AA), at a molar ration of about 10% to about 30%.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: May 6, 2014
    Assignee: The Johns Hopkins University
    Inventors: Anirban Maitra, Georg Feldmann, Savita Bisht
  • Publication number: 20130115165
    Abstract: Polymeric nanoparticles with a hydrophobic core and a hydrophilic shell are formed from: 1) N-isopropylacrylamide (NIPAAM), at a molar ratio of about 50% to about 90%, and preferably 60% for specific delivery routes such as oral or parenteral; either water-soluble vinyl derivatives like vinylpryolidone (VP) or vinyl acetate (VA), or water insoluble vinyl derivaties like methyl methacrylate (MMA) or styrene (ST), at a molar ratio of about 10% to about 30%; and acrylic acid (AA), at a molar ration of about 10% to about 30%.
    Type: Application
    Filed: October 12, 2012
    Publication date: May 9, 2013
    Inventors: Anirban Maitra, Georg Feldmann, Savita Bisht
  • Patent number: 8313777
    Abstract: Polymeric nanoparticles with a hydrophobic core and a hydrophilic shell are formed from: 1) N-isopropyl acrylamide (NIPAAM), at a molar ratio of about 50% to about 90%, and preferably 60% for specific delivery routes such as oral or parenteral; either water-soluble vinyl derivatives like vinylpyrolidone (VP) or vinyl acetate (VA), or water insoluble vinyl derivatives like methyl methacrylate (MMA) or styrene (ST), at a molar ratio of about 10% to about 30%; and acrylic acid (AA), at a molar ratio of about 10% to about 30%. The formed nanoparticles may be optionally surface functionalized using reactive groups present in AA, including PEGylation, or conjugation of moieties such as chemotherapeutics, contrasting agents, antibodies, radionucleides, ligands, and sugars, for diagnostic, therapeutic, and imaging purposes. The polymeric nanoparticles are preferably dispersed in aqueous solutions.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: November 20, 2012
    Assignee: The Johns Hopkins University
    Inventors: Anirban Maitra, Georg Feldmann, Savita Bisht
  • Publication number: 20080107749
    Abstract: Polymeric nanoparticles with a hydrophobic core and a hydrophilic shell are formed from: 1) N-isopropyl acrylamide (NIPAAM), at a molar ratio of about 50% to about 90%, and preferably 60% for specific delivery routes such as oral or parenteral; either water-soluble vinyl derivatives like vinylpyrolidone (VP) or vinyl acetate (VA), or water insoluble vinyl derivatives like methyl methacrylate (MMA) or styrene (ST), at a molar ratio of about 10% to about 30%; and acrylic acid (AA), at a molar ratio of about 10% to about 30%. The formed nanoparticles may be optionally surface functionalized using reactive groups present in AA, including PEGylation, or conjugation of moieties such as chemotherapeutics, contrasting agents, antibodies, radionucleides, ligands, and sugars, for diagnostic, therapeutic, and imaging purposes. The polymeric nanoparticles are preferably dispersed in aqueous solutions.
    Type: Application
    Filed: October 5, 2007
    Publication date: May 8, 2008
    Inventors: Arniban Maitra, Georg Feldmann, Savita Bisht
  • Patent number: 6632960
    Abstract: Diaryliodonium salts are disclosed, as well as a method for preparing them, in which one of the aryl groups bonded to the positively-charged iodine ion contains a methyl substituent, and the other one contains a hydroxyl-substituted alkoxy group. The salts are synthesized from (o, m, or p)-iodotoluene, as opposed to iodobenzene, and therefore do not pose a carcinogenic risk. In addition, the present salts are unexpectedly more soluble in most organic solvents, as well as in nonpolar monomers, than the corresponding benzene catalysts. The salts are useful as cationic photoinitiators, cationic thermal initiators (often combined with a cocatalyst, e.g. copper), and as starting materials in the synthesis of urethane-containing iodonium salts.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: October 14, 2003
    Assignees: Goldschmidt AG, Polyset Chemical Company Inc.
    Inventors: James V. Crivello, Georg Feldmann-Krane, Sascha Oestreich
  • Patent number: 6617365
    Abstract: The invention relates to the use of silicone-polyether copolymers of the formula I as surface-active substances in the production of polyurethane foams.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: September 9, 2003
    Assignee: Goldschmidt AG
    Inventors: Georg Burkhart, Georg Feldmann-Krane, Ingo Fleute-Schlachter, Andreas Weier
  • Publication number: 20020193619
    Abstract: Diaryliodonium salts are disclosed, as well as a method for preparing them, in which one of the aryl groups bonded to the positively-charged iodine ion contains a methyl substituent, and the other one contains a hydroxyl-substituted alkoxy group. The salts are synthesized from (o, m, or p)- iodotoluene, as opposed to iodobenzene, and therefore do not pose a carcinogenic risk. In addition, the present salts are unexpectedly more soluble in most organic solvents, as well as in nonpolar monomers, than the corresponding benzene catalysts. The salts are useful as cationic photoinitiators, cationic thermal initiators (often combined with a cocatalyst, e.g. copper), and as starting materials in the synthesis of urethane-containing iodonium salts.
    Type: Application
    Filed: June 21, 2002
    Publication date: December 19, 2002
    Applicant: Polyset Company, Inc.
    Inventors: James V. Crivello, Georg Feldmann-Krane, Sascha Oestreich
  • Patent number: 6297331
    Abstract: The invention relates to novel organosiloxanyl derivatives of the general formula: to a process for preparing these derivatives, to the use thereof for preparing organomodified siloxanes and to the use thereof as paint additives.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: October 2, 2001
    Assignee: Th. Goldschmidt AG
    Inventors: Georg Feldmann-Krane, Wolfgang Josten, Rolf-Dieter Langenhagen, Gerhard Reusmann, Stefan Silber, Werner Spratte, Stefan Stadtmüller
  • Publication number: 20010004646
    Abstract: The invention relates to the use of silicone-polyether copolymers of the formula I 1
    Type: Application
    Filed: November 29, 2000
    Publication date: June 21, 2001
    Inventors: Georg Burkhart, Georg Feldmann-Krane, Ingo Fleute-Schlachter, Andreas Weier
  • Patent number: 5977282
    Abstract: Oraganopolysiloxanes of the general formula ##STR1## where R.sup.1 =identical or different aliphatic or aromatic hydrocarbon radicals,R.sup.2 =CH.sub.2 CH.sub.2 O(CR.sup.4 R.sup.5).sub.x OC(O)CR.sup.6 .dbd.CHR.sup.7, whereR.sup.4, R.sup.5, R.sup.6 and R.sup.7can be identical or different radicals and are each a H or alkyl radical, branched or unbranched, having up to a total of 6 C atoms and x has a value from 3 to 11, where --(CR.sup.4 R.sup.5)-- can also be a cyclic aliphatic or aromatic radical,R.sup.3 =R.sup.2 or R.sup.1,a=0 to 50 andb=0 to 500,but at least one radical R.sup.2 is attached terminally and/or laterally.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: November 2, 1999
    Assignee: Th. Goldschmidt AG
    Inventors: Thomas Ebbrecht, Georg Feldmann-Krane, Stefan Silber, Stefan Stadtmuller
  • Patent number: 5863966
    Abstract: Radiation-curing printing inks which comprise organopolysiloxanes of the general formula ##STR1## in which R.sup.1 =an alkyl radical having 1 to 8 carbon atoms,R.sup.2 =a group of the formula--CH.sub.2 --CH.sub.2 --C(O)O--R--(OC(O)--CH.dbd.CH.sub.2).sub.x-1and/or--CH.dbd.CH--C(O)O--R--(OC(O)--CH.dbd.CH.sub.2).sub.x-1in which x is an integer and is at least 2, and R is a hydrocarbon radical which optionally has alkoxy groups,R.sup.3 =R.sup.1 or R.sup.2,n=30 to 150,m=0 to 3, preferably 0,in quantities of from 0.01 to 3% by weight, based on the ink formulation.
    Type: Grant
    Filed: September 6, 1996
    Date of Patent: January 26, 1999
    Assignee: Th. Goldschmidt AG
    Inventors: Thomas Ebbrecht, Georg Feldmann-Krane, Peter Lersch, Stefan Silber
  • Patent number: 5733971
    Abstract: Aqueous and radiation-curable printing varnishes and printing inks, are disclosed which contain special polyoxyalkylene polysiloxane copolymers. These printing varnishes and printing inks have improved scratch resistance, a higher gliding ability and an extremely low tendency to foam, so that the production of printing inks proceeds without problems and, at the same time, an optically attractive typography can be obtained.
    Type: Grant
    Filed: January 7, 1997
    Date of Patent: March 31, 1998
    Assignee: Th. Goldschmidt AG
    Inventors: Georg Feldmann-Krane, Petra Hinrichs, Stefan Silber, Susanne Struck
  • Patent number: 5401871
    Abstract: Organopolysiloxane polyethers with increased resistance to hydrolysis are prepared. Furthermore, a method of rendering an aqueous system hydrolysis-resistant and exhibiting increased wetting property utilizing such polysiloxane polyethers as wetting agents in aqueous systems is described. Aqueous coating systems containing such polyethers exhibit increased wetting property and are resistant to alkaline and acidic hydrolysis.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: March 28, 1995
    Assignee: Th. Goldschmidt AG
    Inventors: Georg Feldmann-Krane, Werner Hohner, Dietmar Schaefer, Stefan Silber