Abstract: A method for the additive manufacture of at least one three-dimensional object by means of a system, wherein a coating unit is moved onward through any number of segments and/or subsegments such that the coating unit performs at least one idle run. A system for the additive manufacture of three-dimensional objects, and a computer-readable storage medium are also disclosed.

Abstract: The invention relates to a method for additively manufacturing at least one three-dimensional object (1) by means of a system, wherein a coating unit (40) is stopped in a segment (A; B; C; D) and/or one of its sub-segments (A1; A2; B1; B2; C1; C2; D1; D2) as a parking segment. Furthermore, the invention relates to a system for additive manufacturing of three-dimensional objects and a computer-readable storage medium.

Abstract: An apparatus for manufacturing a three-dimensional object by a layer-by-layer solidification of building material at the points corresponding to the cross-section of the object to be manufactured in a respective layer. The apparatus includes a process chamber in which the object is to be built up layer by layer by selectively solidifying layers of a building material in a build area, a gas supply device, and a recirculating air filter device, wherein the apparatus comprises a pressure stabilization device configured to keep the pressure in the process chamber substantially constant.

Abstract: The invention relates to a flow system and a flow arrangement for flowing a building field of a manufacturing device for additive manufacturing of three-dimensional components by layer-by-layer application and locally selective solidification of a building material within the building field by means of a plurality of irradiation units. Furthermore, the invention relates to a corresponding manufacturing device and a manufacturing method.

Abstract: A method for the additive manufacture of at least one three-dimensional object by means of a system, wherein a coating unit is moved onward through any number of segments and/or subsegments such that the coating unit performs at least one idle run. A system for the additive manufacture of three-dimensional objects, and a computer-readable storage medium are also disclosed.

Abstract: The invention relates to a method for additively manufacturing at least one three-dimensional object (1) by means of a system, wherein a coating unit (40) is stopped in a segment (A; B; C; D) and/or one of its sub-segments (A1; A2; B1; B2; C1; C2; D1; D2) as a parking segment. Furthermore, the invention relates to a system for additive manufacturing of three-dimensional objects and a computer-readable storage medium.

Abstract: The invention relates to a method for the additive manufacturing of at least one three-dimensional object (1) by means of a system comprising a coating unit (40) and at least two irradiation units (50), the irradiation areas of which partially overlap or are adjacent to each other, wherein the irradiation areas are adapted so that a total irradiation period for selectively solidifying one or more layers of applied build-up material (30) is minimised as required. The invention further relates to a system for additive manufacturing of three-dimensional objects and a computer-readable storage medium.

Abstract: A device (1) for producing a three-dimensional object (2) through layer-wise solidifying of build-up material (13) at positions (43) corresponding to a cross-section of the object (2) to be produced in a respective layer comprises a coating device (12-14) for applying a layer of the build-up material (13) on a working plane (10), a solidifying device (20) for the selective solidifying of the build-up material (13) in the applied layer and a gas suction nozzle (34) for extracting gas from the device (1) by suction. The gas suction device (34) is thereby movably arranged and the device (1) is designed to control or to regulate a movement and/or orientation of the gas suction nozzle (34) as a function of a number of reference positions (51, 53, 55a, 55b, 55c, 55d).

Abstract: A method for controlling the direction of gas suctioning is carried out in a device (1) for producing a three-dimensional object (2) by selectively solidifying building material (13) layer by layer. The device (1) comprises an application device (12-14) for applying a layer of the building material (13) to a build area in a working plane (10), a solidifying device (20) for selectively solidifying the building material (13) in the applied layer, and at least two gas nozzles (40) which are arranged at the edge of the build area. The gas nozzles (40) are switchable into a function for suctioning gas from the device (1) and to a functionless state, and are switched depending on an operating state of the device (1).

Abstract: A method for producing a three-dimensional object (2, 10) and a boundary region (8, 9, 18) by layer-wise applying and solidifying of at least one building material, wherein the three-dimensional object (2, 10) is produced with a first generative production method on the basis of a first building material and the boundary region (8, 9, 18) is produced with a second generative production method, which is different from the first generative production method, on the basis of a second building material. The first generative production method comprises the steps: applying a layer of the first building material on a building base (11, 12) or on an already previously applied layer, selectively solidifying the applied layer at positions corresponding to the cross-section of the object (2, 10) in the respective layer and repeating the steps of applying and selectively solidifying until the object (2, 10) is completed.

Abstract: A modular system (1) for producing a three-dimensional object (2) by layerwise application and selective solidification of a pulverulent build material (13) contains a first module (30, 34-36; 40, 41) suitable for carrying out a first process used for the production of the three-dimensional object (2), and at least a second and a third module (30, 34-36; 40,41) suitable for carrying out a further process used for the production of the three-dimensional object (2). The first to third modules (30, 34-36; 40, 41) are configured so that the second or the third module, or both, can selectively and replaceably be connected to the first module in such a way that their housings are coupled to one another directly.

Abstract: After the manufacturing of an object by layer-wise solidification from a powder, this object is displaced into a container together with the powder surrounding the object, and is closed by a plate, which is positioned below the object during the manufacturing of the object.

Abstract: An apparatus for manufacturing a three-dimensional object by a layer-by-layer solidification of building material at the points corresponding to the cross-section of the object to be manufactured in a respective layer. The apparatus includes a process chamber in which the object is to be built up layer by layer by selectively solidifying layers of a building material in a build area, a gas supply device, and a recirculating air filter device, wherein the apparatus comprises a pressure stabilization device configured to keep the pressure in the process chamber substantially constant.

Abstract: A method for producing a three-dimensional object (2, 10) and a boundary region (8, 9, 18) by layer-wise applying and solidifying of at least one building material, wherein the three-dimensional object (2, 10) is produced with a first generative production method on the basis of a first building material and the boundary region (8, 9, 18) is produced with a second generative production method, which is different from the first generative production method, on the basis of a second building material. The first generative production method comprises the steps: applying a layer of the first building material on a building base (11, 12) or on an already previously applied layer, selectively solidifying the applied layer at positions corresponding to the cross-section of the object (2, 10) in the respective layer and repeating the steps of applying and selectively solidifying until the object (2, 10) is completed.

Abstract: A method for controlling the direction of gas suctioning is carried out in a device (1) for producing a three-dimensional object (2) by selectively solidifying building material (13) layer by layer. The device (1) comprises an application device (12-14) for applying a layer of the building material (13) to a build area in a working plane (10), a solidifying device (20) for selectively solidifying the building material (13) in the applied layer, and at least two gas nozzles (40) which are arranged at the edge of the build area. The gas nozzles (40) are switchable into a function for suctioning gas from the device (1) and to a functionless state, and are switched depending on an operating state of the device (1).

Abstract: A device (1) for producing a three-dimensional object (2) through layer-wise solidifying of build-up material (13) at positions (43) corresponding to a cross-section of the object (2) to be produced in a respective layer comprises a coating device (12-14) for applying a layer of the build-up material (13) on a working plane (10), a solidifying device (20) for the selective solidifying of the build-up material (13) in the applied layer and a gas suction nozzle (34) for extracting gas from the device (1) by suction. The gas suction device (34) is thereby movably arranged and the device (1) is designed to control or to regulate a movement and/or orientation of the gas suction nozzle (34) as a function of a number of reference positions (51, 53, 55a, 55b, 55c, 55d).

Abstract: A device (20) for unpacking a three-dimensional object (2), produced in an interchangeable container (5) and/or on a construction platform (7) by applying layers of a construction material (11) in powder form and by selective hardening thereof, from the surrounding unhardened powder (9) contains a rotating device (22) for holding the interchangeable container (5) and/or the construction platform (7), which rotating device is able to rotate the interchangeable container (5) and/or the construction platform (7) through an angle of at least 90° out of the upright position.

Abstract: A modular system (1) for producing a three-dimensional object (2) by layerwise application and selective solidification of a pulverulent build material (13) contains a first module (30, 34-36; 40, 41) suitable for carrying out a first process used for the production of the three-dimensional object (2), and at least a second and a third module (30, 34-36; 40,41) suitable for carrying out a further process used for the production of the three-dimensional object (2). The first to third modules (30, 34-36; 40, 41) are configured so that the second or the third module, or both, can selectively and replaceably be connected to the first module in such a way that their housings are coupled to one another directly.

Abstract: After the manufacturing of an object by layer-wise solidification from a powder, this object is displaced into a container together with the powder surrounding the object, and is closed by a plate, which is positioned below the object during the manufacturing of the object.

Abstract: An immunotoxin for use in, and a method for treating a subject having a cancer associated with malignant B-lineage cells or an autoimmune condition, are disclosed. The immunotoxin includes (a) an anti-CD19 antibody lacking an Fc fragment, (b) a modified exotoxin A protein having both Domains II and III, but lacking Domain I, and (c) a peptide linker joining the C-terminal end of the antibody to the N-terminal end of the modified exotoxin A protein. The linker is substantially resistant to extracellular cleavage. The modified exotoxin A protein may be further modified to include a C-terminal KDEL sequence (SEQ ID NO: 6) that promotes transport of the protein to the endoplasmic reticulum of cells that have taken up the immunotoxin.