Patents by Inventor Georg Fráter
Georg Fráter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20040068145Abstract: A process for the purification of 1,3-diketones comprising reacting a 1,3-diketone with an earth metal or alkaline earth metal complexing agent in an organic solvent, isolating, washing and decomposing the resulting complex, and isolating the purified 1,3-diketone.Type: ApplicationFiled: August 1, 2003Publication date: April 8, 2004Inventors: Georg Frater, Ulrich Huber
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Patent number: 6627763Abstract: The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.Type: GrantFiled: June 12, 2002Date of Patent: September 30, 2003Assignee: Givaudan SAInventors: Denise Anderson, Georg Fráter, Frank Kumli
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Patent number: 6569411Abstract: Serine carbonates of formula I are precursors for organoleptic compounds, masking agents and antimicrobial agents. Further they are alternative substrates for malodor producing enzymes. The symbols in formula I are defined in claim 1.Type: GrantFiled: August 15, 2002Date of Patent: May 27, 2003Assignee: The Gillette CompanyInventors: Georg Frater, Denise Anderson, Frank Kumli, Jens Wittenberg, Virginia Streusand Goldman
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Publication number: 20030068358Abstract: A preparation for oral administration, in which plant material is comminuted and treated by mixing thoroughly with an extractant. After mixing, porous inorganic particles are added to the resulting suspension, thoroughly mixed with mixture and dried. The preparation provides a homogeneous distribution of the active ingredient as well as long stability and good bioavailability of the active ingredient.Type: ApplicationFiled: September 30, 2002Publication date: April 10, 2003Applicant: Bogar AGInventors: Marijke Frater-Schroder, Georg Frater
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Patent number: 6521797Abstract: The present invention is an oxime carboxylic acid derivative having the formula I: wherein n is 1 or 0, X is O, R2 and R3 being part of an oxime R2R3C═NOH are individually, substituted or unsubstituted, branched or unbranched alkyl-, alkenyl-, akinyl-, cycloalkyl-, cycloalkenyl-, or aromatic radical and contain less than 30 carbon atoms, and R1 is a substituted or unsubstituted, branched or unbranched alkyl-, alkenyl-, akinyl-, cycloalkyl-, cycloalkenyl-, alkoxyalkyl-, aryloxyaryl-, alkoxyaryl-, aryloxyalkyl-, or aromatic radical, or XnR1 is which are useful as precursors for the delivery of organoleptic compounds, especially for flavors, fragrances and masking agents, and/or antimicrobial compounds.Type: GrantFiled: August 17, 1999Date of Patent: February 18, 2003Assignee: Givaudan AGInventors: Denise Anderson, Georg Frater
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Publication number: 20020193269Abstract: The present invention relates to compounds with protected hydroxy groups of formula (I) 1Type: ApplicationFiled: June 12, 2002Publication date: December 19, 2002Applicant: Givaudan SA, a Switzerland corporationInventors: Denise Anderson, Georg Frater, Frank Kumli
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Patent number: 6479682Abstract: The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.Type: GrantFiled: October 11, 2000Date of Patent: November 12, 2002Assignee: Givaudan SAInventors: Denise Anderson, Georg Fráter, Frank Kumli
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Patent number: 6437150Abstract: The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.Type: GrantFiled: July 13, 2000Date of Patent: August 20, 2002Assignee: Givaudan SAInventors: Denise Anderson, Georg Fráter, Frank Kumli
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Patent number: 6369248Abstract: Compounds having formula (I) in which n is 1, 2 or 3 and R1 to R6 represent, independently, branched or unbranched, substituted or unsubstituted alkyl-, alkenyl-, alkinyl-, cycloalkyl-, cycloalkenyl- or aromatic-radicals or hydrogen wherein these radicals may in addition contain one or more —O— and/or (a)—groups, whereby one or two rings can be built by the combination of the respective R1 to R6 and this/these ring(s) can be further substituted by an alkyl-group, in which X is either O and R7 represents a radical of an alcohol or phenol R7OH, or X is N and R7 represents the radical of an amine R7′R7″NH, whereby R7′ and R7″ represent independently, branched or unbranched, substituted or unsubstituted alkyl-, alkenyl-, alkinyl-, cycloalkyl-, cycloalkenyl- or aromatic radicals or either R7′R7″ may be hydrogen, whereby the amine is a fragrant amine or the amine has more than 9 C atoms, whereby R7 of the alcohol or phenol and R7′ and/or R7″ of the aType: GrantFiled: December 20, 1999Date of Patent: April 9, 2002Assignee: Givaudan SAInventors: Denise Anderson, Georg Frater
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Patent number: 6348618Abstract: The beta-ketoesters of formula I are useful as precursors for organoleptic compounds, especially for flavors, fragrances and masking agents and antimicrobial compounds.Type: GrantFiled: August 18, 2000Date of Patent: February 19, 2002Assignee: Givaudan Roure (International) SAInventors: Denise Anderson, Georg Fráter
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Patent number: 6326349Abstract: Disclosed are compounds of formula I having a strong musk-like odor: In formula I, R1 and R2 are hydrogen or methyl, with the proviso that when R1 is methyl, R2 is hydrogen, and when R1is hydrogen, R2 is methyl. The compounds of formula I may be in the Z- and/or in the E-form. Methods of making the compounds of formula I and compositions containing such compounds are also disclosed.Type: GrantFiled: September 1, 1999Date of Patent: December 4, 2001Assignee: Givaudan Roure (International) SAInventors: Daniel Helmlinger, Georg Fráter, Urs Müller
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Patent number: 6306818Abstract: The invention relates to fragrance precursors, In particular, the invention relates to the use of several classes of compounds which may act as fragrance precursors, e,g., in cosmetic products such as deodorants and antiperspirants and in laundry products such as detergents and fabric softners. These compounds are odorless, but upon contacting the skin as example, in skin care compositions or in personal care compositions, produce fragrances. The compounds also produce fragrances when used in the presence of lipases, e.g. as used in (laundry) detergents, thus providing a prolongation of the fabric scenting effect. The compounds under consideration are compounds of the formula I: The substituents are defined in the specification.Type: GrantFiled: May 24, 1999Date of Patent: October 23, 2001Assignee: Givaudan Roure (International) SAInventors: Denise Anderson, Georg Frater
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Patent number: 6297211Abstract: The invention includes (6E)- and (6Z)-isomers of 3,6-dimethyloct-6-en-1-ols and 6-ethyl-3-methyloct-6-en-1-ols and their mixtures. The mixtures are free from their corresponding oct-5-ene double bond isomers. Processes of preparing odorant compositions containing these compositions are also provided.Type: GrantFiled: February 11, 2000Date of Patent: October 2, 2001Assignee: Givaudan Roure (International) SAInventors: Georg Frater, Philip Kraft, Urs Müller
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Patent number: 6284929Abstract: The invention relates to compounds of the general formula in which R1 to R7 are, independently, H, methyl or ethyl, R8+R9 together form methylene (—CH2—) or a single bond, or R1+R2 together form —(CH2)n—, with n being 3 or 4, or R3+R5 or R5+R7 represent methylene or a single bond; and the presence of at least one cyclopropane ring in the molecule is compulsory and the side chain can be saturated or contains one double bond in position &agr;,&bgr; or &bgr;,&ggr;, a process for the manufacture of these compounds, compounds used to perform the process and the use of these compounds as an odorant or as an ingredient of an odorant composition.Type: GrantFiled: October 5, 2000Date of Patent: September 4, 2001Assignee: Givaudan Roure (International) SAInventors: Jerzy A. Baigrowicz, Georg Frater
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Patent number: 6262287Abstract: Organosiloxane fragrance precursor compounds having at least one organosiloxane unit of the formula or a mixture thereof and if any other siloxane unit(s) in the said organosiloxanes being present this/these is/are of formula wherein R represents a substituted or unsubstituted C1-8 alkyl group or a substituted or unsubstituted aryl group; R″ represents a hydrogen atom, a monovalent C1-8 hydrocarbon group or a monovalent C1-8 halogenated hydrocarbon group; R1 represents a hydrogen atom or a substituted or unsubstituted C1-8 alkyl group or a substituted or unsubstituted aryl group or a bond connecting CR1 and CR3; R3 represents a hydrogen atom or a substituted or unsubstituted C1-8 alkyl group or a substituted or unsubstituted aryl group; represents (CR42)n whereby R4 represents a substituted or unsubstituted C1-8 alkyl group or a substituted or unsubstituted aryl group or a hydrogen atom and whereby n is from 0-20 and each R4 is the same or different; OR2 represType: GrantFiled: May 12, 1998Date of Patent: July 17, 2001Assignee: Givaudan-Roure (International) SAInventors: Denise Anderson, Georg Frater
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Patent number: 6258854Abstract: The invention discloses ketones of formula I: wherein, Y is an optionally substituted alkyl, cycloalkyl, or cycloalkylalkyl, wherein each alkyl group is straight or branched and each alkyl and cycloalkyl group is saturated or unsaturated; R1 is hydrogen or a C1-6 alkyl group that is substituted, saturated or unsaturated, straight or branched; A is a chromophoric substituted aromatic ring or ring system; n is an integer; and with the proviso that formula I is not 2-ethoxy-1-phenyl-ethanone. These compositions are useful for the delivery of organoleptic compounds, especially of flavors, fragrances, masking agents and antimicrobial compounds.Type: GrantFiled: September 1, 1999Date of Patent: July 10, 2001Assignee: Givaudan Roure ( International ) SAInventors: Denise Anderson, Georg Fráter
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Patent number: 6255276Abstract: The invention is concerned with odorant compositions which contain macrocycles, namely 15- to 17-membered compounds of the formula: wherein the dotted line signifies an optional additional bond, X and Y stand for methylene or C2-12-polymethylene, optionally substituted with an additional methyl group, and A signifies hydrogen or methyl in the case of the unsaturated compounds and methyl in the case of the saturated compounds, with the proviso that the unsaturated compounds are present to more than 80% in the cis form when A signifies hydrogen and are present to more than 50% in the cis form when A signifies methyl, with the exception of Z-oxacyclopentadec-6-en-2-one (15-membered ring), Z-oxacycloheptadec-8-en-2-one (17-membered ring), and Z-oxacycloheptadec-11-en-2-one (17-membered ring), a process for the manufacture of the compounds of formula I and the use of the compounds of formula I as odorants.Type: GrantFiled: February 16, 2000Date of Patent: July 3, 2001Assignee: Givauden Roure (International) S.A.Inventors: Georg Frater, Daniel Helmlinger, Urs Müller
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Patent number: 6242413Abstract: The invention relates to bicyclic aldehydes and ketones of formula (I): wherein n is 1 or 2; R1 and R4 are independently H or CH3; and R2 and R3 are independently H, CH3 or CH2CH3 The invention also provides odorant compositions containing at least one compound of formula (I). A process for the manufacture of R1-methyl substituted compounds of formula (I) having a bridgehead-positioned double bond, as well as intermediates thereof is also provided.Type: GrantFiled: June 2, 1999Date of Patent: June 5, 2001Assignee: Givaudan Roure (International) S.A.Inventors: Georg Frater, Philip Kraft
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Patent number: 6239314Abstract: The invention relates to compounds of the general formula in which R1 to R7 are, independently, H, methyl or ethyl, R8+R9 together form methylene (—CH2—) or a single bond, or R1+R2 together form —(CH2)n—, with n being 3 or 4, or R3+R5 or R5+R7 represent methylene or a single bond; and the presence of at least one cyclopropane ring in the molecule is compulsory and the side chain can be saturated or contains one double bond in position &agr;,&bgr; or &bgr;,&ggr;, a process for the manufacture of these compounds, compounds used to perform the process and the use of these compounds as an odorant or as an ingredient of an odorant composition.Type: GrantFiled: October 5, 2000Date of Patent: May 29, 2001Assignee: Givaudan Roure (International) SAInventors: Jerzy A. Bajgrowicz, Georg Frater
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Patent number: 6235943Abstract: The invention relates to compounds of the general formula in which R1 to R7 are, independently, H, methyl or ethyl, R8+R9 together form methylene (—CH2—) or a single bond, or R1+R2 together form —(CH2)n—, with n being 3 or 4, or R3+R5 or R5+R7 represent methylene or a single bond; and the presence of at least one cyclopropane ring in the molecule is compulsory and the side chain can be saturated or contains one double bond in position &agr;,&bgr; or &bgr;,&ggr;, a process for the manufacture of these compounds, compounds used to perform the process and the use of these compounds as an odorant or as an ingredient of an odorant composition.Type: GrantFiled: October 5, 2000Date of Patent: May 22, 2001Assignee: Givaudan Roure (International) SAInventors: Jerzy A. Bajgrowicz, Georg Frater