Patents by Inventor Georg Halder

Georg Halder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD
    Patent number: 12552772
    Abstract: The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.
    Type: Grant
    Filed: June 5, 2024
    Date of Patent: February 17, 2026
    Assignees: SPRINGWORKS THERAPEUTICS, INC., KATHOLIEKE UNIVERSITEIT LEUVEN, VIB VZW
    Inventors: Bart Vanderhoydonck, Arnaud Marchand, Stephen L. Gwaltney, II, Stéphane Spieser, Wim Smets, Aurélie Candi, Matthias Versele, Georg Halder
  • 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD
    Publication number: 20250115574
    Abstract: The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.
    Type: Application
    Filed: June 5, 2024
    Publication date: April 10, 2025
    Inventors: Bart VANDERHOYDONCK, Arnaud MARCHAND, Stephen L. GWALTNEY, II, Stéphane SPIESER, Wim SMETS, Aurélie CANDI, Matthias VERSELE, Georg HALDER
  • 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD
    Patent number: 12030866
    Abstract: The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.
    Type: Grant
    Filed: December 23, 2022
    Date of Patent: July 9, 2024
    Assignees: SPRINGWORKS THERAPEUTICS, INC., KATHOLIEKE UNIVERSITEIT LEUVEN, VIB VZW
    Inventors: Bart Vanderhoydonck, Arnaud Marchand, Stephen L. Gwaltney, Stéphane Spieser, Wim Smets, Aurélie Candi, Matthias Versele, Georg Halder
  • 2-Pyrazole Anilines and Related Analogs for Inhibiting YAP/TAZ-TEAD
    Publication number: 20230278982
    Abstract: The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.
    Type: Application
    Filed: December 23, 2022
    Publication date: September 7, 2023
    Inventors: Bart VANDERHOYDONCK, Arnaud MARCHAND, Stephen L. GWALTNEY, II, Stéphane SPIESER, Wim SMETS, Aurélie CANDI, Matthias VERSELE, Georg HALDER
  • CANCER REGRESSION BY INDUCING A REGENERATION-LIKE RESPONSE
    Publication number: 20210379088
    Abstract: The invention relates to the field of oncology, in particular to the field of anti-cancer agents or mechanisms. In particular, activation of a regeneration-like response, such as by activating expression and/or function of YAP and/or TAZ in an organ carrying a tumor or cancer is capable of causing regression of that tumor or cancer.
    Type: Application
    Filed: December 3, 2019
    Publication date: December 9, 2021
    Inventors: Georg Halder, Iván Moya