Abstract: The invention provides for a RANKL-specific antagonistic agent recognizing human platelet-expressed receptor activator of nuclear factor kappa-B ligand (pRANKL), for use in treating a cancer patient to prevent or reduce premetastatic lesions in blood.

Abstract: The invention provides for a RANKL-specific antagonistic agent recognizing human platelet-expressed receptor activator of nuclear factor kappa-B ligand (pRANKL), for use in treating a cancer patient to prevent or reduce premetastatic lesions in blood.

Abstract: A smoke munition or smoke grenade which can be fired from a launcher, for example a grenade launcher, and has at least one active charge for producing smoke as a protection for ships. To achieve the effect that the active charge of the smoke grenade can be delivered quickly and safely for the ship's crew and the active compound thereof can be converted completely into smoke even after hitting the water, the invention proposes providing the active charge with a floating aid, which can be deployed before the active charge hits the water and prevents the active charge from sinking and prevents the active compound that produces the smoke from becoming wet.

Abstract: A convertible vehicle having a displaceable top and a top storage space, which can be closed using a storage space cover, as well as a wind deflector, which is displaceable between a retracted stowage position and at least one erected function position and can have an inner frame on which a wind deflector function element is spanned. The wind deflector can have an outer frame, to which the inner frame is pivotably mounted and which is pivotably mounted to the storage space cover.

Abstract: A convertible top of a cabriolet vehicle includes a convertible top rod assembly movable between a closed position spanning a vehicle interior and a storage position. The top rod assembly includes a link arrangement on opposing sides of the assembly. The link arrangement includes a main link and a main column pivotably mounted on a main bearing, and a front-side first link element and a second link element. The second link element is rearward of the first link element in the closed position and connected to the first link element by a joint arrangement, wherein the first link element being pivotable relative to the second link element by an actuating link extending along the second link element. A knee lever arrangement connected to the first link element, the second link element, and the actuating link includes a closing bolt.

Abstract: A smoke munition or smoke grenade which can be fired from a launcher, for example a grenade launcher, and has at least one active charge for producing smoke as a protection for ships. To achieve the effect that the active charge of the smoke grenade can be delivered quickly and safely for the ship's crew and the active compound thereof can be converted completely into smoke even after hitting the water, the invention proposes providing the active charge with a floating aid, which can be deployed before the active charge hits the water and prevents the active charge from sinking and prevents the active compound that produces the smoke from becoming wet.

Abstract: A top of a convertible motor vehicle includes a linkage movable between a closed position spanning a vehicle interior and a storage position uncovering the vehicle interior to the top A linkage arrangement having first and second pivot components is on opposing sides of the linkage and pivotably mounted at a rear main bearing. A rotatable drive wheel is coupled to the two pivot components. When the drive wheel is rotated, the first pivot component is always subjected to a drive torque, whereas the second pivot component, as a function of the position of a control element guided by structure fixed relative to the main bearing, is either held in place or is subjected to a drive torque.

Abstract: The invention provides for a RANKL-specific antagonistic agent recognizing human platelet-expressed receptor activator of nuclear factor kappa-B ligand (pRANKL), for use in treating a cancer patient to prevent or reduce premetastatic lesions in blood.

Abstract: A top of a convertible vehicle includes a top linkage adjustable between a closed position and a storage position. The top linkage is stored in a rear-side top storage space, which is closable by a storage space lid, which is pivotably mounted on a vehicle-fixed single-part or multipart main bearing via a link mechanism on each of its two sides with respect to a vertical longitudinal center plane of the top. The top linkage has a linkage mechanism on each of its two sides with respect to the vertical longitudinal center plane of the top. Each linkage mechanism is pivotably mounted on the respective vehicle-fixed main bearing driven by a main drive arranged on the main bearing. The link mechanisms of the storage space lid are arranged on both sides and driven by the main drive arranged on the respective main bearing.

Abstract: A convertible vehicle having a displaceable top and a top storage space, which can be closed using a storage space cover, as well as a wind deflector, which is displaceable between a retracted stowage position and at least one erected function position and can have an inner frame on which a wind deflector function element is spanned. The wind deflector can have an outer frame, to which the inner frame is pivotably mounted and which is pivotably mounted to the storage space cover.

Abstract: A top of a convertible vehicle is includes a top linkage adjustable between a closed position and a storage position. The top linkage is stored in a rear-side top storage space, which is closable by a storage space lid, which is pivotably mounted on a vehicle-fixed single-part or multipart main bearing via a link mechanism on each of its two sides with respect to a vertical longitudinal center plane of the top. The top linkage has a linkage mechanism on each of its two sides with respect to the vertical longitudinal center plane of the top. Each linkage mechanism is pivotably mounted on the respective vehicle-fixed main bearing driven by a main drive arranged on the main bearing. The link mechanisms of the storage space lid are arranged on both sides and driven by the main drive arranged on the respective main bearing.

Abstract: A spacing adjustment device between a first and a second component of a convertible roof assembly for a vehicle. The space adjusting device may have a body having a first thickness at a first end and a second, greater thickness, at a second end; an inner surface configured to conform to an exterior contour of the first component and an exterior surface opposite the inner surface and configured to conform to the contours of the second component; the body having at least two sections each having a different thickness between the inner and exterior surfaces; wherein the thickness of the at least two sections increases in step wise manner from the first end to the second end of the body.

Abstract: A convertible top of a cabriolet vehicle includes a convertible top rod assembly movable between a closed position spanning a vehicle interior and a storage position. The top rod assembly includes a link arrangement on opposing sides of the assembly. The link arrangement includes a main link and a main column pivotably mounted on a main bearing, and a front-side first link element and a second link element. The second link element is rearward of the first link element in the closed position and connected to the first link element by a joint arrangement, wherein the first link element being pivotable relative to the second link element by an actuating link extending along the second link element. A knee lever arrangement connected to the first link element, the second link element, and the actuating link includes a closing bolt.

Abstract: A convertible top of a cabriolet vehicle includes a convertible top rod assembly, which can be adjusted between a closed position spanning the vehicle interior and a storage position. The top trod assembly includes a link arrangement on both sides of a vertical longitudinal center plane of the convertible top. The link arrangement includes a main link and a main column, which are pivotably mounted on a vehicle-fixed main bearing, and a front-side first link element and a second link element, which is arranged rearward of the first link element in the closed position and is connected to the first link element by a joint arrangement. The first link element can be pivoted relative to the second link element by an actuating link extending along the second link element and can be secured against pivoting relative to the second link element in the closed position by a locking element.

Abstract: A top of a convertible motor vehicle includes a linkage movable between a closed position spanning a vehicle interior and a storage position uncovering the vehicle interior to the top A linkage arrangement having first and second pivot components is on opposing sides of the linkage and pivotably mounted at a rear main bearing. A rotatable drive wheel is coupled to the two pivot components. When the drive wheel is rotated, the first pivot component is always subjected to a drive torque, whereas the second pivot component, as a function of the position of a control element guided by structure fixed relative to the main bearing, is either held in place or is subjected to a drive torque.

Abstract: A top of a convertible motor vehicle includes a linkage movable between a closed position spanning a vehicle interior and a storage position uncovering the vehicle interior to the top A linkage arrangement having first and second pivot components is on opposing sides of the linkage and pivotably mounted at a rear main bearing. A rotatable drive wheel is coupled to the two pivot components. When the drive wheel is rotated, the first pivot component is always subjected to a drive torque, whereas the second pivot component, as a function of the position of a control element in a control slot that is fixed relative to the main bearing, is either held in place or is subjected to a drive torque.

Abstract: A top for a convertible vehicle having at least one roof element, which is displaceable in relation to a vertical longitudinal center plane of the roof, is guided slidably in the longitudinal direction of the roof on both sides at one guide rail, respectively, said guide rail being arranged at a respective lateral roof beam, a rear roof cassette being displaceable between an erected position for adjoining, in the rear, to the lateral roof beams in the longitudinal direction of the roof and a storage position that is lowered with respect to the former position and the roof cassette accommodating the roof element in the uncovering position thereof, as well as a sealing arrangement that is arranged in the region of the roof opening and seals a vehicle interior off with respect to a vehicle environment in the closed position of the roof element.

Abstract: A cabriolet top having a top linkage which can be adjustable between a closed position, in which it spans a vehicle interior space, and an open position having at both sides of a vertical vehicle longitudinal central plane, in each case one link arrangement assigned a closure unit which can be adjusted by means of an actuating device between a locking and unlocking position and which, in its locking position in the closed position of the top linkage, secures a front bow, which connects the two link arrangements to one another, to a front cowl of the vehicle by means of a locking hook. The locking hook can be connected via a first joint to a first locking link pivotable about an axle fixed to the front bow and via a second joint to a second locking link pivotable about an axle fixed to the front bow.

Abstract: A spacing adjustment device between a first and a second component of a convertible roof assembly for a vehicle. The space adjusting device may have a body having a first thickness at a first end and a second, greater thickness, at a second end; an inner surface configured to conform to an exterior contour of the first component and an exterior surface opposite the inner surface and configured to conform to the contours of the second component; the body having at least two sections each having a different thickness between the inner and exterior surfaces; wherein the thickness of the at least two sections increases in step wise manner from the first end to the second end of the body.

Abstract: A modular roof assembly includes a pair of side rails configured for attachment to longitudinal roll bar members of a vehicle frame by at least one fastener. The side rails extend a direction along a length of the vehicle frame and include at least one guideway to slidably receive transverse tensioning bows and a track car for a soft top and include at least one attachment member adapted to latchably receive at least one hard top panel.